Miniaturization of Liquid Chromatography: Why Do We Do It?

TECHNICAL NOTE 72277 Capillary-flow LC-MS: combining high sensitivity, robustness, and throughput Authors Alexander Boychenko, Stephan Meding, Wim Decrop, Martin Ruehl, Remco Swart Thermo Fisher Scientific, Germering, Germany Keywords Capillary-flow LC-MS, capLC-MS, sensitivity, throughput, direct injection, preconcentration onto trap cartridge, robustness,…

TECHNICAL NOTE 72777 High-throughput capillary-flow LC-MS proteomics with maximum MS utilization Authors Contents Alexander Boychenko1, Christopher Pynn1, Bart van den Berg1, Tabiwang N. Arrey2, Mike Baynham 3, Wim Decrop1, Martin Ruehl1 1. Introduction.............................................................................................. 2 Thermo Fisher Scientific, Germering, Germany 2.…

high retention time precision. This allowed to multiplex ASGYTFTSYNMHWVK targeted assays by using 1791.8165 narrow column STYYGGDWYFNVWGAGTTVTVSAASTK 2889.3372 retention time windows and obtain highly reproducible results. Methods Q Exactive HF UltiMate 3000 RSLCnano Liquid Chromatography SSSTAYMQLSSLTSEDSAVYYCAR 2677.1848 Light chain chimeric…

C H R O M ATO G R A P H Y P rod u ct S p ecif ica t ions Acclaim PepMap and Acclaim PepMap RSLC Columns for High-Resolution Peptide Mapping Relative Abundance 100 • Highest sensitivity in…