Method Optimization for the Analysis of Monoclonal Antibodies by Size-Exclusion Chromatography

Application News LabSolutions™ MD: Software for Efficient Method Development based on Analytical Quality by Design Efficient Method Development of Monoclonal Antibody Size Variants by Size Exclusion Chromatography Shinichi Fujisaki and Chihiro Hosoi User Benefits  The separation between monoclonal antibody…

High Performance Liquid Chromatograph Application News NexeraTM XS inert Analysis of protein drugs aggregation Using Size Exclusion Chromatography D. Fujimura, E. Ando, R. Suzuki User Benefits  Improving the separation of protein drugs and those aggregates and/or decompositions by suppressing…

APPLICATION NOTE Amy Farrell1, Jonathan Bones1, and Ken Cook2 1 NIBRT, Dublin, Ireland; 2 Thermo Fisher Scientific, Hemel Hempstead, UK Key words MAbPac SEC-1, monoclonal antibody, mAb, aggregation analysis, biotherapeutics, size-exclusion chromatography Goal Analysis of protein aggregation of five important…

[ APPLICATION NOTEBOOK ] SIZE-EXCLUSION CHROMATOGRAPHY (SEC) OF PEPTIDES, PROTEINS, AND AAVs [ SIZE-EXCLUSION CHROMATOGRAPHY ] [ SIZE-EXCLUSION CHROMATOGRAPHY ] Introduction Gel-permeation chromatography (GPC), size-exclusion chromatography (SEC), and gel-filtration chromatography (GFC) are commonly used terms to describe a liquid chromatographic…