Generation of a Novel Digestion Protocol for Enhanced Proteome Coverage

Valeria Barattini, Phillip Humphryes, Thermo Fisher Scientific, Runcorn, UK Key Words Peptides, proteins, thyroglobulin, monoclonal antibody, mAb, biomarker, SMART Digest, protein digestions, proteomics, Accucore C18, biopharmaceutical, biomolecules, biotherapeutics Goal To demonstrate how the Thermo Scientific™ SMART Digest™ kit makes it…

SMART Digest and SMART Digest ImmunoAffinity Kits Smarter protein preparation SMART Digest and SMART Digest ImmunoAffinity kits Smarter protein preparation The Thermo Scientific™ SMART Digest™ and the SMART Digest ImmunoAffinity (IA) kits are designed for biomarker and bio-therapeutic characterization and…

Rapid Automated Peptide Mapping Kate Erickson Application Scientist The world leader in serving science Why is there a growth in biotherapeutics? • 8/10 drugs in 2016 Biologics • Biopharma growing rapidly ~10% over the next 5 years • $160 Billion…

Protein digestion for peptide mapping and quantitation Overview of SMART Digest and SMART Digest ImmunoAffinity Kits SMART Digest and SMART Digest ImmunoAffinity kits Thermo Scientific™ SMART Digest™ and the SMART Digest™ ImmunoAffinity (IA) kits are designed for biomarker and bio-therapeutic…