LC-MS: Robust long-term Vanquish Neo UHPLC system operation enabling high-performance high-pressure nanoLC separations

LC-MS TECHNICAL NOTE Vanquish Neo UHPLC system sets new performance standards for single-shot nanoLCMS bottom-up proteomics Authors biomarker discovery and precision medicine. The enormous variety and dynamic range of proteins found in biofluids such Runsheng Zheng , Christopher Pynn ,…

Technical note | 000816 Liquid chromatography ZebraWash: An innovative approach in the Vanquish Neo UHPLC system to reduce trap column carryover Authors Goal Runsheng Zheng, Christopher Pynn, Demonstrate the superior performance of the ZebraWash procedure in Thermo Martin Samonig, Wim…

Long-term stability and reproducibility of nano-, capillary- and micro-flow LC-MS separations: the impact of hardware and separation column Christopher Pynn1, Runsheng Zheng1; Tabiwang Arrey2; Amirmansoor Hakimi3; Alec Valenta1; Susanne Moyer1 1Thermo Fisher Scientific, Germering, Germany; 2Thermo Fisher Scientific, Bremen, Germany;…

TECHNICAL NOTE LC-MS Vanquish Neo UHPLC system-to-system reproducibility ensures consistent and reliable results in nanoLC-MS proteomics Authors We investigated the intra- and inter-system variability for typical nanoLC-MS applications using the new Vanquish Neo UHPLC Christopher Pynn , Gisela Noack ,…