Application of Vacuum Jacketed UHPLC Columns Coupled with Mass Spectrometry in High Throughput Pharmaceutical Analysis

[ PRODUCT SOLUTION ] Employing ballistic gradients, vacuum jacketed columns and prototype benchtop multi reflecting time-of-flight (MRT) to increase lipidomic throughput whilst maintaining highly confident identifications Authors: Matthew E. Daly 1, Nyasha Munjoma1, Rob S. Plumb2 , Jason Hill2 ,…

HIGH THROUGHPUT PLASMA PROFILING OF HUMAN LIVER DISEASE SAMPLES USING RAPID CHROMATOGRAPHY AND A MULTIREFLECTING TIME-OF-FLIGHT MASS SPECTROMETER Authors: Adam M King1, Ana Sanchez-Lorenzo2, Yuriy Pyatkivskyy3, Emma Marsden-Edwards1, Elizabeth Want2 Affiliations: 1Waters Corporation, Wilmslow, Cheshire, UK. 2Department of Metabolism, Digestion…

EMPLOYING BALLISTIC GRADIENTS, VACUUM JACKETED COLUMNS AND A NOVEL MRT TO INCREASE LIPIDOMIC THROUGHPUT WHILST MAINTAINING HIGHLY CONFIDENT IDENTIFICATIONS Matthew E. Daly1, Nyasha Munjoma1, Rob S. Plumb2, Jason Hill2, Nick Tomczyk1, Lee A. Gethings1, Richard Lock1 1 Waters Corporation, Wilmslow,…

Using a vacuum jacketed column with a multi reflecting time-of-flight MS to increase extractables analysis throughput whilst maintaining identification confidence Rachel Sanig1, Lee A. Gethings1, Jayne Kirk1, Richard Lock1, Bindesh Shrestha2 Waters Corporation, UK1, Waters Corporation, US2 • INTRODUCTION METHODS…