DESI Cyclic IMS Enables the Detection and Spatial Distribution of Proteins in Tuberculosis Granulomas

SPATIAL DISTRIBUTION AND IDENTIFICATION OF PROTEIN IN TUBERCULOSIS GRANULOMAS USING DESI AND CYCLIC ION MOBILITY Hernando Olivos1, Emmanuelle Claude1, Véronique Dartois2,3 and Claire L. Carter2,4 1 Waters Corporation, Milford, MA 2 Center for Discovery and Innovation, Hackensack Meridian Health Nutley,…

BENEFITS OF HIGH RESOLUTION ION MOBILITY SEPARATION ON THE CYCLIC IMS FOR DESI MASS SPECTROMETRY IMAGING 1Susan Slade, 1Emmanuelle Claude; 1Waters Corporation, Wilmslow, UK Results Introduction a) Desorption DESITM is a powerful and sensitive MS ionisation technique for the profiling…

ADVANTAGES OF HIGH RESOLUTION ION MOBILITY ON THE CYCLIC IMS FOR DESI MASS SPECTROMETRY IMAGING 1 Susan Slade, 1Emmanuelle Claude. 1 Waters Corporation, Wilmslow, UK. INTRODUCTION RESULTS TM Desorption DESI is a powerful and sensitive MS ionisation technique for the…

25 YEARS MALDI Integrating Ultra-High Speed MALDI-TOF and MALDI MRMS Imaging For Spatial Proteomics MALDI imaging is a powerful technology that allows the detection of analytes from tissue while preserving their spatial distribution Introduction Cystic fibrosis (CF) is inherited in…