Agilent LC AND LC/MS Parts and Supplies catalog

Importance of the topic

High-performance liquid chromatography (HPLC) and HPLC coupled with mass spectrometry (LC/MS) are cornerstone techniques for chemical analysis across food safety, environmental testing, pharmaceuticals, forensics, materials science and life sciences.
Reliable columns, consumables and instrumentation accessories are critical to deliver reproducible separations, accurate quantitation and maximum uptime.

Objectives and overview of the catalog

This catalog presents a comprehensive portfolio of Agilent’s LC and LC/MS products, supplies and service offerings. It is designed to help labs:

• Optimize system performance and sensitivity
• Maintain robust, leak-free fluid paths
• Simplify preventive maintenance
• Enable high-throughput workflows from routine HPLC to advanced UHPLC and LC/MS

Methodology and instrumentation

Agilent’s LC platforms span from routine HPLC to ultra-high pressure (UHPLC) systems:

• 1220 Infinity LC: cost-effective, 600 bar pump, 80 Hz detector speed
• 1260 Infinity LC: high confidence, 600 bar binary and quaternary pumps, ultra-sensitive UV detection
• 1290 Infinity LC: highest throughput UHPLC, 1200 bar, intelligent method emulation

LC/MS solutions cover single quadrupole, triple quadrupole, TOF and Q-TOF instruments (6100–6500 series), offering mass accuracies to <2 ppm, resolutions >50 000, and sensitivity enhancements (Jet Stream, iFunnel).

Main results and discussion

Key advances include:

• Ultra-low dispersion capillaries (<0.075 mm id) and optimized fluid routing to preserve the performance of sub-2 µm columns
• Bio-inert PEEK-lined and titanium capillaries for proteins and biomolecules
• Extended lifetime detector lamps (2 000 h) for UV/DAD instruments
• Integrated pump, sampler and column racks to save bench space and minimize extra-column volume
• CrossLab consumables compatible with non-Agilent HPLC systems to simplify inventory

Benefits and practical applications

Agilent’s holistic approach delivers:

• Improved quantitation and peak shape through optimized fittings, filters and flow cells
• Easier preventive maintenance with bundled PM kits for pumps, autosamplers and valves
• Reduced downtime via remote monitoring (Remote Advisor) and guaranteed 10-year instrument value
• Seamless compatibility of capillaries, tubing and fittings across brands

Used instrumentation

• LC systems: Agilent 1220, 1260, 1290 Infinity LC
• LC/MS systems: Agilent 6100, 6200, 6400, 6500 series
• Low-flow LC: 1260 Capillary and Nanoflow LC
• Microfluidic: 1260 HPLC-Chip/MS
• Consumables: ZORBAX and Poroshell columns, CrossLab capillaries, fittings, in-line filters
• Detectors: VWD, DAD, FLD, RID, ELSD, MS

Future trends and applications

Emerging areas include high-throughput UHPLC, multidimensional LC, omics-driven workflows, native MS of proteins, lab automation and remote diagnostics. Continued miniaturization and bio-inert fluid paths will be critical for sensitive analyses of biomolecules, metabolomics and trace-level quantitation.

Conclusion

Agilent’s integrated LC and LC/MS portfolio, combined with comprehensive supplies, consumables and service solutions, enables laboratories to maintain peak performance, reproducibility and reliability across a broad range of applications.

References

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