High-throughput MALDI-MS based read-out of high-density droplet microarrays facilitating next generation on-chip drug discovery

MALDI Mass Spectrometry Application News Modified target surface to enhance performance during MALDI analysis Andreas Baumeister1, Maximilian Benz2, Wolfgang Sipos2 1 Shimadzu Europa GmbH, 2 Aquarray GmbH User Benefits u Higher number of samples on the target increases the throughput.…

© Title Image - Analytik Jena Kinase inhibition screening by label-free mass spectrometry employing the MALDI PharmaPulse HTS solution Bruker´s MALDI PharmaPulse solution, integrating the rapifleX high-speed MALDI-TOF instrument with the dedicated MALDI PharmaPulse software suite, represents an emerging technology…

Novel MALDI-TOF MS Workflow for Ultrahigh-Throughput Screening of Different Analytes at Each Position on a Plate Novel Synthesis Screening workflow in MALDI PharmaPulse software that was developed for screening of synthetic chemical reactions is applied to screen a custom library…

Profiling mammalian cell differentiation by MALDI-TOF MS: Developing a highly reproducible and robust sample preparation workflow In this application note, we present a universal workflow for mammalian cell MALDI-TOF MS analysis in order to distinguish between ground-state naïve and differentiating…