Using Parallel Accumulation Serial Fragmentation (PASEF) to speed up untargeted 4D lipidomics LC-MS/MS workflows

4D-Lipidomics™ workflow for increased throughput Lipid profiling from complex lipid extracts can be a challenging and time consuming task. The high complexity of samples and co-elution of isobaric or isomeric compounds complicate the confident annotation of lipids. The presented 4D-Lipidomics…

Investigating the increased lifespan in C. elegans daf-2 mutants by 4D-Lipidomics The small nematode Caenorhabditis elegans is one of the premier biomedical model organisms and employed in many aspects of basic and applied science Introduction Typical application areas for C.…

Intensity (arb. unit) 132% 0% 100% PS 38:1 m/z 816.5747 ± 0.0122 1/K0 1.433 ± 0.01 Intensity (arb. unit) Mobility [1/K0] 136% 0% 100% PE 20:1_22:6 m/z 816.5517 ± 0.0122 1/K0 1.404 ± 0.01 m/z 1 mm CCS-aware SpatialOMx® enables…

Product Overview Life Science Mass Spectrometry Innovation with Integrity Mass Spectrometry Empowering Science with Innovation and Integrity As one of the world’s leading analytical instrumentation companies, Bruker offers a broad spectrum of advanced solutions in all fields of research and…