Short gradients with Bruker’s nanoElute coupled to the timsTOF Pro with PASEF — Throughput and deep proteome measurements

timsTOF Pro with PASEF and Evosep One: Maximizing throughput, robustness and analytical depth for shotgun proteomics The timsTOF Pro powered by PASEF enables sequencing speed of > 120 Hz, high sensitivity and robustness as well as an additional dimension of…

Accurate Label-Free Protein Quantitation on the timsTOF Pro with 4D-Proteomics™ The timsTOF Pro platform brings together two unique technologies, namely Trapped Ion Mobility Spectrometry (TIMS) mode operation at the front-end and Parallel Accumulation Serial Fragmentation (PASEF [1]) for data acquisition.…

dia-PASEF® applied on different gradient lengths Data Independent Acquisition (DIA) workflows have gained in popularity as they overcome the issue of stochastic selection of peptide precursors encountered in typical data-dependent approaches (DDA) and thereby promise reproducible and accurate protein identification…

High throughput 4D-Proteomics – Application of dia-PASEF® and the Evosep One for short gradients The timsTOF Pro offers a combination of two unique technologies, namely a 4th dimension provided by Trapped Ion Mobility Spectrometry (TIMS) to enhance ion separation and…