Re-discovering Bacterial Biofilm Heterogeneity with MALDI Imaging Mass Spectrometry

25 YEARS MALDI Integrating Ultra-High Speed MALDI-TOF and MALDI MRMS Imaging For Spatial Proteomics MALDI imaging is a powerful technology that allows the detection of analytes from tissue while preserving their spatial distribution Introduction Cystic fibrosis (CF) is inherited in…

MP-525 Simplified molecular imaging analysis of excreted microbial metabolites using a benchtop MALDI-TOF system Sidrah Rahman1, Michael Nairn2, Tom Abban2, Simona Salivo2, Matt Openshaw2, Rian L. Griffiths1 1School of Pharmacy, University of Nottingham, Nottingham, UK. 2Shimadzu, Manchester, UK. There has…

25 YEARS MALDI High-performance MALDI imaging analysis of on-tissue digested proteins in mammalian FFPE tissues using the Bruker rapifleX MALDI-TOF/TOF In this application note, we describe a workflow for MALDI Mass Spectrometry Imaging (MSI) of proteins from a variety of…

High-speed MALDI-TOF/TOF imaging of mouse brain tissue performed on intact proteins and after on-tissue digestion The unique flexibility of MALDI-TOF/TOF systems facilitates tissue imaging of intact proteins as well as of tryptic peptides resulting from on-tissue digestion. While intact protein…