Using Poroshell 300SB-C18 for High-Sensitivity, High-Throughput Protein Analysis on the Agilent LC/MSD

Making the Leap Small Molecule – Biologics Rita Steed LC Columns Application Engineer June 26, 2018 1 June 26, 2018 Agilent Technologies Outline ➢ Small and/or biomolecules; Similarities/differences ➢ Column Choice ➢ Things to Consider ➢ Method Conditions ➢ Troubleshooting…

Making the Leap Small Molecule – Biologics Rita Steed LC Columns Application Engineer May 8, 2019 1 May 8, 2019 Small molecule – Biologics Agilent Restricted Outline • Small and/or biomolecules; similarities/differences • Column choice • Things to consider •…

Accurate Mass Measurement for Intact Proteins using ESI-oa-TOF Application Note Donghui Yi and Christine Miller Agilent Technologies Jon D. Williams, GlaxoSmithKline Introduction Mass spectrometry (MS) has become a core with an orthogonal-acceleration reflectron time- technology for identification of primary protein…

Maximizing proteome coverage through improved on-line Orbitrap peak determination Graeme C. McAlister1, Christian Thoeing2, Helene L. Cardasis1, Alex S. Hebert3, Romain Huguet1, Philip Remeš1, Andreas Kuehn2, Mike Senko1, Shannon Eliuk1, Joshua J. Coon3, Vlad Zabrouskov1; 1Thermo Fisher Scientific, San Jose,…