N-linked Glycan Characterization and Profiling: Combining the Power of Accurate Mass, Reference Glucose Units, and UNIFI Software for Confident Glycan Assignments

BIOPHARMACEUTICAL PLATFORM SOLUTION Key Applications TABLE OF CONTENTS Biopharmaceutical Platform Solution with UNIFI: Key Applications Intact Protein MS Analysis I Peptide Mapping I Released Glycan Analysis I Bioseparations Biotherapeutic proteins – such as monoclonal antibodies (mAbs), biosimilars, and antibody drug…

WP 023 Automated Glycan Assignment Using Mass Measurement with a Calibrated Retention Time in Glucose Unit Ying Qing Yu1, and Weibin Chen1, Mark Hillard2, Niaobh McLoughlin2 and Pauline M. Rudd2 1. Waters Corporation, Milford USA; 2. National Institute of Bioprocessing…

Waters Application Notes Glycans There are a variety of complementary techniques practiced to get the complete story about a glycoprotein. Each technique varies in complexity and provides a different layer of information. Method complexity This application notebook highlights a body…

[ APPLICATION NOTE ] Combining RapiFluor-MS and UNIFI Scientific Information System for a Total N-linked Glycan Solution for Innovator vs. Biosimilar Infliximab Comparisons William R. Alley, Jr. and Ying Qing Yu Waters Corporation, Milford, MA, USA APPLICATION BENEFITS INTRODUCTION This…