Targeted High Resolution Quantification with Tof-MRM and HD-MRM

High Definition Multiple Reaction Monitoring: The Application of Quadrupole Ion Mobility Time-of-Flight Mass Spectrometry for Targeted Proteomics Studies Dominic Helm,1 Christopher J. Hughes,2 James I. Langridge,2 Keith Richardson,2 Arkadiusz Grzyb,2 Jason Wildgoose,2 and Bernhard Kuster1 1 Technische Universität München, Freising,…

High Definition Data Directed Analysis (HD-DDA) Nick Tomczyk, Alistair Wallace, Keith Richardson, Arkadiusz Grzyb, and Jason Wildgoose G OA L High Definition Data Directed Analysis provides the To improve routine discovery workflows with High Definition Data Directed Analysis (HD-DDA), a…

Increasing Sensitivity for Tof-MS Detection of Polychlorinated Biphenyls (PCBs) Using Tof MRM Lauren Mullin and Adam Ladak, Waters Corporation, Milford, MA, USA G OA L Tof MRM affords increased sensitivity while Tof MRM affords increased sensitivity while maintaining the ability…

Quantitation by High Resolution Mass Spectrometry: Using Target Enhancement and Tof-MRM to Achieve Femtogram-level On-column Sensitivity for Quantitation of Drugs in Human Plasma Yun W. Alelyunas, Mark D. Wrona, Russell J. Mortishire-Smith, Nick Tomczyk, and Paul D. Rainville Waters Corporation,…