High Mass Loading of Peptides with Hybrid Particle C18 Columns and Acetic Acid Mobile Phases

Increasing Peak Capacity in Reversed-Phase Peptide Separations with Charged Surface Hybrid (CSH) C18 Columns Matthew A. Lauber, Stephan M. Koza, and Kenneth J. Fountain Waters Corporation, Milford, MA, USA A P P L I C AT I O N B…

MAIN MENU TABLE OF CONTENTS [ APPLICATIONS NOTEBOOK ] BIOSEPARATIONS Tools, Techniques, and Insights into Biopharmaceutical Analysis INT RODUCTION Biopharmaceuticals have emerged as a dominant class due to their specificity and efficacy. T he production of biopharmaceuticals, however, is distinctly…

Peptide Mapping and Small Protein Separations with Charged Surface Hybrid (CSH) C18 and TFA-Free Mobile Phases Matthew A. Lauber, Stephan M. Koza, Kenneth J. Fountain Waters Corporation, Milford, MA, USA A P P L I C AT I O N…

[ APPLICATION NOTE ] Selecting a Reversed-Phase Column for the Peptide Mapping Analysis of a Biotherapeutic Protein Stephan M. Koza and Erin E. Chambers Waters Corporation, Milford, MA, USA APPLICATION BENEFITS ■■ ■■ Side-by-side performance of ten The peptide mapping…