Analysis of Monoclonal Antibody Digests with the Agilent 1290 Infinity 2D-LC Solution

Analysis of Monoclonal Antibody Digests with the Agilent 1290 Infinity 2D-LC Solution Part 2: HILIC × RPLC-MS Application Note Biotherapeutics & Biosimilars Authors Abstract Gerd Vanhoenacker1, Koen Sandra1,2 , Trastuzumab (marketed as Herceptin), is a monoclonal antibody used in the…

Identifying Monoclonal Antibody Mutation Sites Using the Agilent 1290 Infinity II 2D-LC Solution with Q-TOF LC/MS Application Note Biopharmaceuticals and Biosimilars Authors Abstract Koen Sandra, Gerd Vanhoenacker, In recent years, 2D-LC has been highly promising for the detailed characterization Mieke…

Biopharma Compendium Accelerate Your CQA Efficiency and Approach it with Multi-Attribute Methodology Breakthroughs to Increase the Efficiency of Critical Quality Attribute (CQA) Testing and Allow for a Multi- Attribute Method (MAM) Production of therapeutic monoclonal antibodies (mAbs) relies on living…

Characterizing Antibody-Drug Conjugates and Assigning Drug Conjugation Sites Using the Agilent 1290 Infinity II 2D-LC Solution Combined with the Agilent 6530 Quadrupole Time-of-Flight LC/MS System Application Note Biopharmaceuticals Authors Abstract Koen Sandra, Gerd Vanhoenacker, Antibody-drug conjugates (ADCs) are a promising…