Comprehensive Characterization of the N and O-Linked Glycosylation of a Recombinant Human EPO

Waters Application Notes Glycans There are a variety of complementary techniques practiced to get the complete story about a glycoprotein. Each technique varies in complexity and provides a different layer of information. Method complexity This application notebook highlights a body…

Characterization of EPO N-Glycans using RapiFluor-MS and HILIC Profiling Rajasekar R. Prasanna, Rajiv Bharadwaj, Matthew A. Lauber, Stephan M. Koza, and Erin E. Chambers Waters India Pvt. Ltd, Bangalore, India Waters Corporation, Milford, MA, USA G OA L The analysis…

MAIN MENU TABLE OF CONTENTS [ APPLICATIONS NOTEBOOK ] BIOSEPARATIONS Tools, Techniques, and Insights into Biopharmaceutical Analysis INT RODUCTION Biopharmaceuticals have emerged as a dominant class due to their specificity and efficacy. T he production of biopharmaceuticals, however, is distinctly…

[ GLYC AN ANALYSIS SOLUTIONS ] The Next Generation of Glycan Sample Preparation and Analysis [ GLYC AN ANALYSIS SOLUTIONS ] What if... identifying WHERE glycans are present on a glycoprotein becomes part of your routine workflow? 1 [ GLYC…