Mass-Directed Isolation of a Synthetic Peptide Using the ACQUITY QDa Detector

[ APPLICATION NOTE ] Small Scale Peptide Isolation Using UPLC with Mass-Directed Purification Jo-Ann M. Jablonski and Andrew J. Aubin Waters Corporation, Milford, MA, USA APPLICATION BENEFITS ■■ ■■ ■■ Mass-directed small scale purification is a useful technique for isolating…

Mass-Directed Isolation of Sulfa Compounds from an Antibiotic Mixture with an ACQUITY QDa Detector Jo-Ann M. Jablonski, Andrew J. Aubin Waters Corporation, Milford, MA, USA G OA L Mass-directed purification with an ACQUITY QDa Detector To illustrate the utility of…

[ APPLICATION NOTEBOOK ] IMPURITIES Developing Safe and Effective Drugs INT RODUCTION NAVIGATION T he pharmaceutical industry is integral in maintaining public health by providing therapeutic and preventative medicines. T he cornerstones of bringing new medicines to market are quality,…

Strategies for Improving Impurity Isolation Using Large Volume Loading and Easy Method Development in Preparative Chromatography Jo-Ann M. Jablonski, Andrew J. Aubin, and Wendy Harrop Waters Corporation, Milford, MA, USA T ECHNOLOGY BENEFIT S ■■ The amount of impurity introduced…