Charge Reduction Electron Transfer Dissociation (crETD) and Ion Mobility for Deconvolution of Protein Mass Spectra and Conformational Analysis

Top-down Monoclonal Antibody (mAb) Analysis Using CID and ETD Fragmentation and the UNIFI Scientific Information System Min Du,1 Martin DeCecco,2 Henry Shion,1 Laetitia Denbigh2 1 Waters Corporation, Milford, MA, USA, 2 Waters Corporation, Wilmslow, UK A P P L I…

Analysis of Isomeric Permethylated Lacto-oligosaccharides Using Electron Transfer Dissociation Combined with Ion Mobility MS Jonathan P. Williams,1 Jeffery M. Brown,1 and Prof. Catherine E. Costello2 Waters Corporation, Manchester, UK and 2 Boston University, Boston, MA, USA 1 A P P…

Application Note Biopharma Comprehensive Approaches to Higher-Order Structure of Intact Proteins by Native Mass Spectrometry Authors Caroline S. Chu, Patrick D. Perkins, Christian Klein, and Andrew Gieschen Agilent Technologies, Inc. Abstract This application note presents different approaches to native mass…

Technical note | 003497 Structural biology Decipher intricate glycoproteins using data-independent acquisition-proton transfer charge reduction and native top-down mass spectrometry Authors Introduction Weijing Liu, Yuqi Shi, Christopher Mullen, The SARS-CoV-2 pandemic underscores the urgent need for rapid viral glycoprotein Julian…