Routine MS Detection for USP Chromatographic Methods

[ APPLICATION NOTE ] Mass Detection Coupled to a USP Method for Lidocaine and Prilocaine Cream Using Multi-dimensional Liquid Chromatography Margaret Maziarz, Claude Mallet, Paul Rainville, and Mark Wrona Waters Corporation, Milford, MA, USA APPLICATION BENEFITS ■■ ■■ INTRODUCTION Easy…

[ APPLICATION NOTE ] Effective Determination of Pharmaceutical Impurities by Two Dimensional Liquid Chromatography Zhimin Li, Paula Hong, and Patricia McConville Waters Corporation, Milford, MA, USA APPLICATION BENEFITS ■■ ■■ INTRODUCTION Increase productivity through targeted Analysis of many pharmaceutical compounds…

[ APPLICATION NOTEBOOK ] ACQUITY QDa Detector QC APPLICATIONS COMPENDIUM EDITION 2 Dear Colleague The 2013 introduction of the ACQUITY™ QDa™ Detector was a breakthrough in Chromatography and Mass Spectrometry integration. It was the fulfilment of a vision 20 years…

[ APPLICATION NOTEBOOK ] METHOD DEV ELOPMENT The Path to Successful Drug Development Starts with Purposeful Method Development [ INTRODUCTION ] T he Path to Successful Drug Development Starts with Purposeful Method Development The goal of method development in pharmaceutical…