Agilent Biopharma Workflow Solutions

An Integrated Workflow for Automated Calculation of Antibody‑Drug Conjugate (ADC) Drug‑to-Antibody Ratio (DAR) Using Automated Sample Preparation, Agilent MassHunter Walkup, and Agilent MassHunter BioConfirm DAR Calculator Software Application Note Biotherapeutics and Biosimilars Authors Abstract David L. Wong, Tanner Stevenson, and…

Agilent BioHPLC columns Characterization of Antibody-Drug Conjugate Critical Quality Attributes Application compendium Contents Introduction3 Featured application notes 2 PLRP-S Polymeric Reversed-Phase Column for LC/MS Separation of mAbs and ADC (5991-7163EN) 5 Intact- and Peptide-Level Characterization of Trastuzumab Emtansine In Vitro…

Drug-to-Antibody Ratio (DAR) Calculation of Antibody-Drug Conjugates (ADCs) Using Automated Sample Preparation and Novel DAR Calculator Software Application Note Authors Introduction Jing Chen and Steve Murphy Antibody-drug conjugates (ADCs) are a new class of biotherapeutics that represent a rapidly growing…

Application Note Pharma and Biopharma A streamlined drug-to-antibody ratio determination workflow for intact and deglycosylated antibody-drug conjugates Using the Agilent AssayMAP Bravo and Agilent 6545XT AdvanceBio accurate-mass quadrupole time-of-flight LC/MS system Authors Jerry Han, Zach Van Den Heuvel, and Steve…