GC-MS-IRMS: Undisputable results by coupling of GC-IRMS with high-resolution mass spectrometry for final confirmation in sports drug testing

APPLICATION NOTE 30402 A unique tool for metabolite research Q Exactive GC coupled with IRMS (QE GC-IRMS) Authors Goal Dieter Juchelka and Jens GriepRaming, Thermo Fisher Scientific, Bremen, Germany Isotopically labeled metabolites and their corresponding structural information can simultaneously be…

APPLICATION NOTE Detection of synthetic forms of endogenous anabolic androgenic steroids by GC-C-IRMS Introduction Compound-specific stable carbon isotope analysis of urinary extracts is a technique that forms part of the standard analysis for doping control as required by the World…

Isotope Ratio Mass Spectrometry SmartNotes How do isotope fingerprints support doping control investigations? While motivated to mark new records with each competition, athletes are more than ever aware of anti-doping policies, rules and regulations. Authorities depend on accurate analysis without…

APPLICATION BRIEF 30520 GC-IRMS: Combat emerging threats in drug abuse with isotope fingerprints Authors Introduction Mario Tuthorn, Dieter Juchelka Thermo Fisher Scientific, Bremen, Germany Drugs in body are converted in metabolites. These metabolites are removed from body in different ways…