Automation of Sample Preparation for Accurate and Scalable Quantification and Characterization of Biotherapeutic Proteins Using the Agilent AssayMAP Bravo Platform

Rapid Antibody Digestion Enabled by Automated Reversed-Phase Desalting on the Agilent AssayMAP Bravo Platform Application Note Authors Introduction Michael Bovee, Adam Krahenbuhl, and Monoclonal antibodies are a rapidly growing class of biotherapeutics whose rigorous characterization by mass spectrometry requires reproducible…

Agilent AssayMAP Bravo Platform Automated protein and peptide sample preparation for mass spec analysis Wash Elute LC/MS pH 2 1.2 1.2 A280 Bind 0.0 0.0 00 Concentration Concentration (µg/mL) (µg/mL) 3000 3000 Superior reproducibility with automated sample prep The Agilent…

Application Note Biopharma Automated MHC-Associated Peptide Enrichment for Immunopeptidomics Analysis Using Agilent AssayMAP Bravo Large Capacity Cartridges Authors Samuel Pollock Genentech, South San Francisco, CA, USA Shuai Wu, Jerry Han, and Steve Murphy Agilent Technologies Inc., Santa Clara, CA, USA…

An Integrated Workflow for Intact and Subunits of Monoclonal Antibody Accurate Mass Measurements Application Note Biotherapeutics and Biosimilars Authors Introduction Shuai Wu and Maryann Shen Monoclonal antibody (mAb) based entities represent a rapidly growing class of biologics that require extensive…