LC/MS of Intact Adeno-Associated Virus Capsid Proteins for Rapid Confirmation of Product Identity

Poster Reprint ASMS 2022 Poster number MP474 Analysis of Adeno-Associated Virus Quality Attributes with LC-FLD-(MS) Brian Liau, Matthew L. Turner, Wendi Hale Agilent Technologies, Santa Clara, CA Introduction Experimental Adeno-associated viral vectors (AAVs) are promising delivery vehicles for the next…

Application Note Pharma & Biopharma Characterization of Viral Vector Particles Using the Agilent 6545XT AdvanceBio LC/Q-TOF Authors Wendi A. Hale and Christopher M. Colangelo Agilent Technologies, Inc., Lexington, MA, USA Roy Hegedus and Norman Garceau Lake Pharma, Worcester, MA, USA…

Consumables Workflow Ordering Guide Adeno-Associated Virus Identity Confirmation in Biopharma by LC/MS While adeno-associated viruses (AAVs) have their own unique set of critical quality attributes, many of the traditional assays used to monitor more established proteinbased therapeutics can still be…

[ APPLICATION NOTE ] Optimizing Adeno-Associated Virus (AAV) Capsid Protein Analysis Using UPLC and UPLC-MS Ximo Zhang, Stephan Koza, Ying Qing Yu, and Weibin Chen Waters Corporation, Milford, MA, USA APPLICATION BENEFITS ■ ■ INTRODUCTION An optimized LC-MS solution for…