Optimizing HILIC-based Analyses of RapiFluor-MS Labeled Sialylated N-Glycans

Waters Application Notes Glycans There are a variety of complementary techniques practiced to get the complete story about a glycoprotein. Each technique varies in complexity and provides a different layer of information. Method complexity This application notebook highlights a body…

Application Note Increased Resolving Power for Acidic Glycans with an MS-Compatible Anion Exchange Reversed Phase Separation Xiaoxiao Liu, Matthew A. Lauber Waters Corporation Abstract Glycosylation are often assigned as critical quality attributes in certain biotherapeutics because they can affect stability,…

MAIN MENU TABLE OF CONTENTS [ APPLICATIONS NOTEBOOK ] BIOSEPARATIONS Tools, Techniques, and Insights into Biopharmaceutical Analysis INT RODUCTION Biopharmaceuticals have emerged as a dominant class due to their specificity and efficacy. T he production of biopharmaceuticals, however, is distinctly…

[ GLYC AN ANALYSIS SOLUTIONS ] The Next Generation of Glycan Sample Preparation and Analysis [ GLYC AN ANALYSIS SOLUTIONS ] What if... identifying WHERE glycans are present on a glycoprotein becomes part of your routine workflow? 1 [ GLYC…