Modernization of a HILIC USP Impurity Method for Cetirizine Hydrochloride Tablets

[ APPLICATION NOTE ] Modernization and Troubleshooting of the USP Organic Impurity Method for Cetirizine Hydrochloride Tablets: Demonstration of XBridge HILIC Robustness Capabilities Across HPLC and UHPLC Instruments Jyotsna Sehajpal and Jacob Fairchild Waters Corporation, Milford, MA, USA APPLICATION BENEFITS…

[ APPLICATION NOTE ] Scaling USP Methods to Smaller Particle Columns on the Alliance HPLC System Amanda B. Dlugasch, Jennifer Simeone, and Patricia R. McConville Waters Corporation, Milford, MA, USA APPLICATION BENEFITS ■■ ■■ INTRODUCTION Reduce run time and solvent…

[ APPLICATION NOTEBOOK ] IMPURITIES Developing Safe and Effective Drugs INT RODUCTION NAVIGATION T he pharmaceutical industry is integral in maintaining public health by providing therapeutic and preventative medicines. T he cornerstones of bringing new medicines to market are quality,…

[ APPLICATION NOTE ] USP Method Modernization for Lidocaine Formulations Using XBridge Columns and Different LC Systems Jyotsna Sehajpal, Jacob Fairchild, and Thomas Swann Waters Corporation, Milford, MA, USA APPLICATION BENEFITS ■■ ■■ Improved resolution of the USP methods The…