Transferring an HPLC Method for Related Substances from Different LC Platforms to an ACQUITY Arc System

Transfer of the HPLC Method for Related Substances Analysis of Metoclopramide HCl from an Agilent 1260 Infinity LC System to an ACQUITY Arc System Margaret Maziarz and Mark Wrona G OA L The ACQUITY Arc System successfully replicated To demonstrate…

HPLC Method Transfer for Analysis of Metoclopramide HCl and Related Substances from an Agilent 1100 Series LC System to an ACQUITY Arc System Margaret Maziarz and Mark Wrona G OA L The ACQUITY Arc System successfully reproduced To transfer an…

[ APPLICATION NOTEBOOK ] IMPURITIES Developing Safe and Effective Drugs INT RODUCTION NAVIGATION T he pharmaceutical industry is integral in maintaining public health by providing therapeutic and preventative medicines. T he cornerstones of bringing new medicines to market are quality,…

Scaling Reverse-Phase and Hydrophilic Interaction Liquid Chromatography (HILIC) Methods to HPLC Authors: Margaret Maziarz, Paul Rainville, Stephanie Harden Affiliations: Waters Corporation, 34 Maple Street, Milford MA 01757 2.0 mL/min Step Time %A 1 Initial 90.0 %B 5.0 %C Curve 5.0…