Transferring RapiFluor-MS Labeled N-Glycan HILIC Separations Between UPLC and HPLC

Waters Application Notes Glycans There are a variety of complementary techniques practiced to get the complete story about a glycoprotein. Each technique varies in complexity and provides a different layer of information. Method complexity This application notebook highlights a body…

MAIN MENU TABLE OF CONTENTS [ APPLICATIONS NOTEBOOK ] BIOSEPARATIONS Tools, Techniques, and Insights into Biopharmaceutical Analysis INT RODUCTION Biopharmaceuticals have emerged as a dominant class due to their specificity and efficacy. T he production of biopharmaceuticals, however, is distinctly…

Robustness of Rapi Fluor-MS N-Glycan Sample Preparations and Glycan BEH Amide HILIC Chromatographic Separations Matthew A. Lauber,1 Michael F. Morris,1 Darryl W. Brousmiche,1 and Stephan M. Koza1 Waters Corporation, Milford, MA, USA 1 A P P L I C AT…

Amide-Bonded BEH HILIC Columns for High Resolution, HPLC-Compatible Separations of N-Glycans Matthew A. Lauber, Stephan M. Koza, Jonathan E. Turner, Pamela C. Iraneta, and Kenneth J Fountain Waters Corporation, Milford, MA, USA A P P L I C AT I…