Improving Detection Limits of ADC Free-Drug Impurities Using the ACQUITY QDa Mass Detector

[ APPLICATION NOTEBOOK ] ACQUITY QDa Detector QC APPLICATIONS COMPENDIUM EDITION 2 Dear Colleague The 2013 introduction of the ACQUITY™ QDa™ Detector was a breakthrough in Chromatography and Mass Spectrometry integration. It was the fulfilment of a vision 20 years…

[ APPLICATION NOTE ] LC-UV-MS-based Synthetic Peptide Identification and Impurity Profiling Using the ACQUITY QDa Detector with ProMass Software Ximo Zhang, Brooke Koshel, Jing Fang, William Alley, Robert Birdsall, and Yinq Qing Yu Waters Corporation, Milford, MA, USA APPLICATION BENEFITS…

Coupling Mass Detection with UV to Improve Method Sensitivity for Esters of Benzenesulfonic Acid in Analysis of Genotoxic Impurities Margaret Maziarz and Mark Wrona Waters Corporation, Milford, MA, USA A P P L I C AT I O N B…

MAIN MENU TABLE OF CONTENTS [ APPLICATIONS NOTEBOOK ] BIOSEPARATIONS Tools, Techniques, and Insights into Biopharmaceutical Analysis INT RODUCTION Biopharmaceuticals have emerged as a dominant class due to their specificity and efficacy. T he production of biopharmaceuticals, however, is distinctly…