Peptide Optimization Using Skyline and the Xevo TQ-XS

Application Note Developing a Quantitative Surrogate Peptide Assay – Peptide mapping through MRM Optimization for Measuring Dulaglutide in a Rat PK Study Caitlin Dunning, Mark Wrona Waters Corporation Abstract Development of fusion protein therapeutics, such as dulaglutide (TRULICITYTM), is rising…

[ APPLICATION NOTEBOOK ] Versatile LC-MS/MS Solutions for the Evolving Bioanalysis Landscape Small Molecules Oligonucleotide Protein/Peptide Therapeutics Software Tools Targeted Imaging LC-MS/MS Solutions to Support Reliable, Sensitive and Efficient Workflows for the Bioanalysis of Drug Modalities Welcome to the Waters…

Application Note Comprehensive Workflow for the Quantification of Peptides and Proteins in Plasma: Semaglutide a Case Study Samantha Ferries Waters Corporation Abstract Over the last two decades we have seen a significant increase in protein and peptide-based therapeutics, with “biologics”…

[ APPLICATION NOTEBOOK ] PEPTIDE AND PROTEIN BIOANALYSIS [ OUR SCIENTISTS ] Yun Alelyunas, PhD Before coming to Waters in 2012, Yun Alelyunas was a principal scientist and team leader at AstraZeneca for 20 years where she was involved in…