Ion Analysis in Drugs (Part 4) - Determination of Counterions (Anions) by Ion Chromatography

Application Handbook Liquid Chromatography Introduction HPLC, UHPLC as well as SFC systems are able to quantitatively analyze substances in mixtures containing multiple ingredients by separating and detecting target substances. They are used to separate, quantify, qualify or purify single components…

LAAN-A-LC-E233 Application News L456 No. High Performance Liquid Chromatography Ion Analysis in Drugs (Part 3) Determination of Counterions (Cations) by Ion Chromatography In Application News No.L387, we introduced examples of impurity ion analysis and counterion analysis in pharmaceuticals using ion…

LAAN-A-LC-E280 Application News L504 No. High Performance Liquid Chromatography Analysis of Ions in Drugs (Part 5) Analysis of Organic Acid Counterions by Ion Exclusion Chromatography The physicochemical and pharmacokinetic properties of active pharmaceutical ingredients change depending on the counterion used,…

Application Note 115 Determination of Trifluoroacetic Acid (TFA) in Peptides INTRODUCTION Trifluoroacetic acid (TFA) is commonly used in the manufacturing process to release synthesized peptides from solid-phase resins. TFA or acetate is also used during reversed-phase HPLC purification of peptides.…