Increased Identification of Extractable and Leachable Compounds by the Use of Chemical Ionization and Custom Databases

Differential Analysis in Screening Assays for Extractable and Leachable Compounds Using an Agilent 7200 GC/Q-TOF System Combined with Data Mining Software Application Note Pharmaceutical Authors Abstract Syed Salman Lateef, The analysis of extractable and leachable (E&L) compounds presents challenges for…

Identification and Comparison of Extractables in Drug Container Closure Systems State-of-the-art Data Mining Process Taking Complete Advantage of Electron Ionization, Chemical Ionization, Collision-induced Dissociation, and Accurate Mass Information using an Agilent 7200 GC/Q-TOF System Application Note Pharmaceutical Author Abstract Syed…

Extractables and Leachables Detected in Ophthalmic Drug Products Detection and Identification Using High-Resolution LC/MS/MS Application Note Pharmaceuticals Author Abstract Syed Salman Lateef Compounds leaching from container closure systems can cause contamination Agilent Technologies, Ltd. to drug substances or products. As…

Application of an Accurate Mass Database and Library for the Screening and Verification of Extractables and Leachables in Pharmaceutical Drug Products Application Note Pharmaceuticals Authors Abstract Syed Salman Lateef1, This Application Note describes the creation of an accurate mass library…