The Waters ACQUITY HPLC System sets the standard for UPLC performance, offering ultra-low dispersion, high-pressure capability, and seamless automation. It's built for high-throughput labs—pharmaceutical, food safety, environmental—seeking unparalleled resolution, precision, and spectral analysis. The system delivers tight retention time reproducibility and rapid gradient mixing, ideal for demanding methods and advanced detection strategies.
Technical Specifications
Binary Solvent Manager (BSM)
- Supports up to four solvents (A1/A2 + B1/B2) with high-pressure vacuum degassing (six channels)
- Flow range: 0.010–2.000 mL/min (0.001 mL increments)
- Max pressure: 15,000 psi up to 1 mL/min, 9,000 psi up to 2 mL/min
- Flow accuracy: ±1% at 0.5 mL/min; precision: 0.075% RSD
- Low system delay volume (<120 µL); gradient profiles: 11 types
Sample Manager – Fixed Loop (SM-FL)
- Injection volume: 0.1–250 µL, in 0.1 µL steps, standard 10 µL loop (others optional)
- Random access: supports plates/vials, <0.5% area RSD
- Temperature controlled: 4–40 °C with ±0.5 °C accuracy, ±1 °C stability
- Built-in wash, needle rinse, load-ahead, and partial loop modes
Column Heater (CH‑A)
- Supports single column up to 4.6 mm ID, 150 mm length
- Temperature range: 20–90 °C, settable in 0.1 °C steps
- Temperature accuracy: ±0.5 °C; stability: ±0.3 °C
- Low-dispersion fittings (18,000 psi) and active pre-heating
PDA Detector
- Wavelength range: 190–500 nm (eλ extends to 800 nm)
- Data rate: up to 80 Hz; noise: ±3 µAU (2 Hz, 230 nm)
- Optical resolution: 1.2 nm; linearity: ≤5% deviation at 2 AU
- Flow cell: intelligent light-guided design, 500 nL volume, 10 mm path
- Detector size: ~34.3 × 19.4 × 60.7 cm; weight ~13.6 kg
Software
- Workstation with original licensed software installed
Highlights
- Ultra-fast, reproducible mixing with high-pressure binary mixing and vacuum degassing
- Precision injection and thermal control across a wide temperature range
- High-resolution column heating with minimal dispersion
- Advanced PDA detection for spectral and multi-wavelength analysis
- Leak detection, diagnostics, and full software integration via Empower/MassLynx
