Agilent 1260 Infinity II Bio-Inert HPLC - Optimized for Biocompatible LC Separations with Maximum Corrosion Resistance
Product Overview
The Agilent 1260 Infinity II Bio-Inert LC System is designed for high-performance analysis of biological macromolecules under harsh conditions. It features a fully metal-free sample flow path and excellent chemical resistance, making it ideal for protein, peptide, oligonucleotide, and mAb analysis. This configuration includes:
- G5654A – Bio-Inert Pump
- G5668A – Bio-Inert Multisampler
- G7116A – Multicolumn Thermostat
- G7115A – Diode Array Detector WR
Key Features & Benefits
- Full Bio-Inert Design: No metal in sample path, ensuring biocompatibility and stability even at high salt or extreme pH (1–13, short term 14)
- High Performance Pumping: Delivers up to 10 mL/min at 600 bar – suitable for conventional to UHPLC columns
- Precise, Low-Carryover Injection: The G5668A multisampler supports vials and MTPs with ultra-low carryover (<9 ppm) and fast cycle times
- Advanced Column Thermostatting: The G7116A enables dual-zone Peltier-based temperature control (4–85 °C), with support for up to 4 columns and integrated valve automation
- Wide-Range UV Detection: The G7115A DAD WR offers fast (120 Hz), high-sensitivity detection across 190–950 nm, with up to 8 signal channels and advanced diagnostics
- Modular, Stackable Design: All modules are compatible with InfinityLab software tools and hardware accessories for automation, diagnostics, and workflow guidance.
System Specifications (Selected)
- Pump (G5654A): 0.01–10 mL/min; up to 600 bar; pH 1–13 (14 short term); titanium wetted parts
- Multisampler (G5668A): Up to 6144 samples; 0.1–1000 µL injection; carryover < 9 ppm; pressure up to 600 bar
- Thermostat (G7116A): 4–85 °C range; ±0.1 °C stability; dual Peltier zones; capacity: 4 × 300 mm columns
- DAD WR Detector (G7115A): 190–950 nm range; 120 Hz data rate; 8 wavelengths; <±0.7·10⁻⁵ AU noise; RFID-enabled
Applications
- SEC, IEX, and RP analysis of proteins, peptides, oligonucleotides
- Native protein separations with minimal adsorption
- High-sensitivity quantification of biologics and biotherapeutics
- Method development under bio-inert and high-salt conditions
