The Agilent 6140 Quadrupole LC/MS system is a high-performance liquid chromatography-mass spectrometry solution designed for laboratories requiring precise, reliable, and sensitive mass analysis. As part of the Agilent 6100 Series, the 6140 model represents the pinnacle of innovation, offering advanced features that cater to a wide range of applications, from routine analyses to complex research tasks.
With its enhanced sensitivity, user-friendly design, and robust construction, the Agilent 6140 provides exceptional performance in environments such as pharmaceuticals, environmental testing, and biochemical research. Equipped with cutting-edge components like an air-cooled turbomolecular pump and a dielectric platinum-plated capillary, the 6140 combines operational efficiency with unparalleled analytical accuracy.
Technical Specification
Design Features:
- Orthogonal-flow sprayer with pneumatic nebulizer: Enhances sensitivity across diverse liquid chromatography (LC) conditions and reduces maintenance.
- High-capacity solvent drying system: Minimizes chemical noise and supports analysis of thermally sensitive compounds by user-controlled gas flow and temperature.
- Dielectric platinum-plated capillary: Allows dynamic optimization of in-source fragmentation and independent adjustment of spray chamber and ion optics.
- Air-cooled turbomolecular pump: Eliminates the need for cooling water, ensuring fast startup, compact size, and improved reliability.
- Fraction collection capability: Supports mass-triggered collection for up to 16 m/z values, using the optional I/O Accessory Module.
Performance Characteristics:
- Mass Range: m/z 10 – 1350
- Mass Accuracy: ± 0.13 u within the calibrated range in scan mode
- Mass Axis Stability: Drift limited to ± 0.1 Da or ± 100 ppm over 12 hours at constant temperature (± 3 °C).
- Scan Speed: Up to 10,000 u/s in fast mode; 2,500 u/s in normal mode
- Sensitivity:
- SIM mode: 1 pg reserpine, 100:1 RMS (20:1 peak-to-peak)
- Scan mode: 50 pg reserpine, 100:1 RMS (20:1 peak-to-peak)
Flow Rates:
- ESI: Up to 1.0 mL/min (without flow splitter)
- APCI: Up to 1.5 mL/min (without flow splitter)
Operating Modes:
- Multisignal acquisition with up to four analysis modes in a single run (positive/negative polarity switching, variable fragmentor voltage, concurrent SIM/scan modes).
Environmental Requirements:
- Temperature: 15 °C to 35 °C (59 °F to 95 °F)
- Relative Humidity: Less than 95% (non-condensing)
Physical Dimensions:
- Height: 65 cm (26 in)
- Width: 39 cm (15 in)
- Depth: 75 cm (29 in)
- Weight: 50 kg (110 lbs)
