The Waters 2410 Differential Refractometer is refractive index (RI) detector designed for use in liquid chromatography applications. This instrument offers reliable detection of analytes based on changes in the refractive index of the eluent. With a measurement range spanning from 5 × 10⁻⁸ to 5 × 10⁻³ RIU, the 2410 excels in sensitivity and versatility, making it suitable for a wide variety of analytical applications. It operates as a standalone device with chart recorders or integrators and integrates seamlessly with Waters’ advanced system controllers or data systems.
The refractometer’s robust design incorporates a countercurrent heat exchanger, temperature-controlled flow cell, and state-of-the-art optics to ensure stable operation even under varying environmental conditions. Key features include auto-zero, auto-purge, built-in pressure relief, and long-life LED light source, all aimed at enhancing reliability and user convenience.
Technical Specification
General Specifications
- Measurement Range: 5 × 10⁻⁸ to 5 × 10⁻³ RIU
- Refractive Index Range: 1.00 to 1.75
- Sensitivity: Capable of detecting small RI differences down to 5 × 10⁻⁸ RIU
- Light Source: Long-life LED (monochromatic)
- Temperature Control:
- Internal oven: 30 to 50 °C (86 to 122 °F)
- External column heaters:
• Ambient to 150 °C (302 °F), steel
• Ambient to 80 °C (176 °F), plastic
Fluidic System
- Flow Cell Composition: Fused quartz, dual-prism design
- Maximum Pressure: 100 psi
- Flow Rate: 0.03 to 10 mL/min
- Cell Volume: 10 μL
- Countercurrent Heat Exchanger: Ensures temperature stability of the sample stream
- Purge Mechanism: Solenoid valve for efficient purging
Optical System
- Optical Configuration: Dual-element photodiode detection with a dual-pass optics bench
- Wavelength: Fixed monochromatic source for consistent RI measurement
Electronics and Controls
- Display: Front-panel LCD with keypad for parameter input
- Parameter Retention: Battery backup for memory retention during power interruptions
- Connectivity:
- IEEE-488 bus for data system integration
- Analog outputs for chart recorders or integrators
Environmental Requirements
- Operating Temperature: 15 °C to 32.2 °C
- Storage Temperature: -40 °C to 70 °C
- Relative Humidity: 20% to 80%, non-condensing
Dimensions and Power
- Dimensions: 11.2 in (W) × 19.8 in (D) × 8.2 in (H)
- Power Supply: 100-240 VAC, 50/60 Hz
- Fuse Rating: 2.0 A, type-specific
Key Features
- Auto-zero and auto-purge functionality
- Temperature-controlled flow cell for stability
- Built-in diagnostics for troubleshooting
- Compatibility with external column heaters
