The Waters ACQUITY I-Class Binary Solvent Manager is a high-performance solvent-delivery module for applications where rapid gradient response, minimal delay, and stable operation at very high pressure are essential. The pump supports selection from four mobile phases, automatically compensates for solvent compressibility, and combines precise high-pressure mixing with integrated degassing and active seal washing. Its low-dwell-volume architecture makes it particularly suitable for fast UPLC methods and sensitive LC/MS coupling.
Technical Specifications
- Module Type: High-pressure binary pump
- Technique: UPLC / LC / LC-MS
- Gradient Formation: High-pressure binary mixing
- Number of Solvents: up to 4, selected as:
- A1 or A2
- B1 or B2
- Operating Flow Range: 0.010–2.000 mL/min
- Flow Increment: 0.001 mL/min
- Maximum Pressure:
- 1,241 bar / 18,000 psi up to 1.0 mL/min
- 827 bar / 12,000 psi up to 2.0 mL/min
- Composition Accuracy: ±0.5% absolute
- Composition Precision: <0.2% RSD or 0.02 min SD
- Flow Precision: 0.075% RSD or 0.01 min SD
- Compressibility Compensation: Automatic and continuous
- Wet Prime Flow: 4 mL/min
- Gradient Profiles:
- linear
- 2 step
- 4 concave
- 4 convex
- Active Seal Wash: Yes
- Primary Check Valve: Intelligent Intake Valve (i²Valve)
Solvent Degassing
The Binary Solvent Manager incorporates a six-channel vacuum degassing system:
- four channels for chromatographic solvents
- two channels for Sample Manager wash solvents
This helps minimize bubble formation, pressure fluctuations, and gradient instability.
Physical Specifications
- Height: 22.9 cm
- Width: 34.3 cm
- Depth: 66.0 cm
- Weight: 26.3 kg
- Power: 100–240 VAC
- Frequency: 50/60 Hz
- Maximum Power Draw: 360 VA
Typical Applications
- Sub-2 µm UPLC separations
- Fast gradient methods
- Pharmaceutical analysis
- Quality control
- LC/MS
- Bioanalytical workflows
- Complex sample analysis
- High-throughput chromatography
