The Agilent Bond Elut Plexa SPE Cartridge (12109301) is a polymer-based solid-phase extraction (SPE) cartridge designed for efficient cleanup and extraction of nonpolar analytes from complex biological matrices. The cartridge features a PS-DVB (polystyrene-divinylbenzene) core combined with a hydroxylated, amide-free surface, which minimizes nonspecific interactions with proteins and lipids.
This design reduces matrix interferences and improves sample cleanliness, helping to reduce ion suppression in LC/MS workflows. Bond Elut Plexa cartridges are particularly suitable for biological samples such as plasma, serum, urine, and whole blood, where matrix effects are often significant.
Technical Specifications
- Part number: 12109301
- Brand: Bond Elut
- Phase: Plexa
- SPE category: Polar enhanced
- Separation mode: Reversed phase
- Primary extraction mechanism: Nonpolar interaction
- Sorbent material: Polymeric (PS-DVB)
- Sorbent mass: 30 mg
- Cartridge volume: 1 mL
- Particle size: 45 µm
- Cartridge material: Polypropylene
- Frit material: Polyethylene
- Frit pore size: 20 µm
- Typical matrices: Aqueous samples, biological fluids, plasma, serum, urine, whole blood
- Compound types: Nonpolar compounds
- SPE format: Straight barrel cartridge
- Package size: 100 cartridges
