Applications focused on LC/HRMS - page 1

Open paper Evaluation of OptiSpray technology and the Orbitrap Astral Zoom mass spectrometer for proteomics applications
LCMS

Evaluation of OptiSpray technology and the Orbitrap Astral Zoom mass spectrometer for proteomics applications

LC/MS, LC/MS/MS, LC/Orbitrap, LC/HRMS
Instrumentation
LC/MS, LC/MS/MS, LC/Orbitrap, LC/HRMS
Manufacturer
Thermo Fisher Scientific
Industries
Proteomics
Open paper LC-MS analysis of intact and subunit-level mAb enabled by a novel monodisperse supermacroporous reversed-phase platform
LCMS

LC-MS analysis of intact and subunit-level mAb enabled by a novel monodisperse supermacroporous reversed-phase platform

LC/MS, LC/MS/MS, LC/Orbitrap, LC/HRMS
Instrumentation
LC/MS, LC/MS/MS, LC/Orbitrap, LC/HRMS
Manufacturer
Thermo Fisher Scientific
Industries
Pharma & Biopharma
Open paper A switchable 2D-LC platform in PAT: routine UV monitoring or MS-based characterization of mAb PQAs directly from the bioreactor
LCMS

A switchable 2D-LC platform in PAT: routine UV monitoring or MS-based characterization of mAb PQAs directly from the bioreactor

LC/MS, LC/MS/MS, LC/Orbitrap, LC/HRMS
Instrumentation
LC/MS, LC/MS/MS, LC/Orbitrap, LC/HRMS
Manufacturer
Thermo Fisher Scientific
Industries
Pharma & Biopharma
Open paper dSEC and dSEC-HRMS Characterization of GLP-1a and Related Peptide Therapeutics
LCMS

dSEC and dSEC-HRMS Characterization of GLP-1a and Related Peptide Therapeutics

GPC/SEC, LC/MS, LC/MS/MS, LC/HRMS, LC/TOF
Instrumentation
GPC/SEC, LC/MS, LC/MS/MS, LC/HRMS, LC/TOF
Manufacturer
Waters
Industries
Pharma & Biopharma
Open paper Advancing Low flow LC/MS for single cell proteomics with variable flow and 50 cm microfabricated pillar array columns
LCMS

Advancing Low flow LC/MS for single cell proteomics with variable flow and 50 cm microfabricated pillar array columns

Consumables, LC columns, LC/MS, LC/MS/MS, LC/Orbitrap, LC/HRMS
Instrumentation
Consumables, LC columns, LC/MS, LC/MS/MS, LC/Orbitrap, LC/HRMS
Manufacturer
Thermo Fisher Scientific
Industries
Proteomics
Open paper Method transfer case study for instrument and LC column migration of the purification and analysis workflow for synthetic oligonucleotides
LCMS

Method transfer case study for instrument and LC column migration of the purification and analysis workflow for synthetic oligonucleotides

Sample Preparation, HPLC, Consumables, LC columns, LC/MS, LC/MS/MS, LC/Orbitrap, LC/HRMS
Instrumentation
Sample Preparation, HPLC, Consumables, LC columns, LC/MS, LC/MS/MS, LC/Orbitrap, LC/HRMS
Manufacturer
Thermo Fisher Scientific
Industries
Pharma & Biopharma
Open paper High-sensitive multi-attribute analysis of ADCs under native conditions by using an online multiple heart-cut 2D-LC-HRAM mass spectrometry system
LCMS

High-sensitive multi-attribute analysis of ADCs under native conditions by using an online multiple heart-cut 2D-LC-HRAM mass spectrometry system

2D-LC, LC/MS, LC/MS/MS, LC/Orbitrap, LC/HRMS, GPC/SEC
Instrumentation
2D-LC, LC/MS, LC/MS/MS, LC/Orbitrap, LC/HRMS, GPC/SEC
Manufacturer
Thermo Fisher Scientific
Industries
Pharma & Biopharma
Open paper Green ion pair and HFIP free method for ASO RNA analysis with GLP compliant automated data handling
LCMS

Green ion pair and HFIP free method for ASO RNA analysis with GLP compliant automated data handling

LC/MS, LC/MS/MS, LC/Orbitrap, LC/HRMS
Instrumentation
LC/MS, LC/MS/MS, LC/Orbitrap, LC/HRMS
Manufacturer
Thermo Fisher Scientific
Industries
Pharma & Biopharma
Open paper Efficient tandem capillary flow LC-MS with short μPAC columns and a single ionization source
LCMS

Efficient tandem capillary flow LC-MS with short μPAC columns and a single ionization source

Consumables, LC columns, LC/MS, LC/MS/MS, LC/Orbitrap, LC/HRMS
Instrumentation
Consumables, LC columns, LC/MS, LC/MS/MS, LC/Orbitrap, LC/HRMS
Manufacturer
Thermo Fisher Scientific
Industries
Proteomics
Open paper Detailed study into ASO impurity analysis, lessons learned, and myths dispelled while moving to compliant platform methods
LCMS

Detailed study into ASO impurity analysis, lessons learned, and myths dispelled while moving to compliant platform methods

LC/MS, LC/MS/MS, LC/Orbitrap, LC/HRMS
Instrumentation
LC/MS, LC/MS/MS, LC/Orbitrap, LC/HRMS
Manufacturer
Thermo Fisher Scientific
Industries
Pharma & Biopharma