Applications from the field of Pharma & Biopharma focused on LC/HRMS - page 1
Open paper LC-MS analysis of intact and subunit-level mAb enabled by a novel monodisperse supermacroporous reversed-phase platform
LCMS
LC-MS analysis of intact and subunit-level mAb enabled by a novel monodisperse supermacroporous reversed-phase platform
LC/MS, LC/MS/MS, LC/Orbitrap, LC/HRMS
Instrumentation
LC/MS, LC/MS/MS, LC/Orbitrap, LC/HRMS
Manufacturer
Thermo Fisher Scientific
Industries
Pharma & Biopharma
Open paper A switchable 2D-LC platform in PAT: routine UV monitoring or MS-based characterization of mAb PQAs directly from the bioreactor
LCMS
A switchable 2D-LC platform in PAT: routine UV monitoring or MS-based characterization of mAb PQAs directly from the bioreactor
LC/MS, LC/MS/MS, LC/Orbitrap, LC/HRMS
Instrumentation
LC/MS, LC/MS/MS, LC/Orbitrap, LC/HRMS
Manufacturer
Thermo Fisher Scientific
Industries
Pharma & Biopharma
Open paper dSEC and dSEC-HRMS Characterization of GLP-1a and Related Peptide Therapeutics
LCMS
dSEC and dSEC-HRMS Characterization of GLP-1a and Related Peptide Therapeutics
GPC/SEC, LC/MS, LC/MS/MS, LC/HRMS, LC/TOF
Instrumentation
GPC/SEC, LC/MS, LC/MS/MS, LC/HRMS, LC/TOF
Manufacturer
Waters
Industries
Pharma & Biopharma
Open paper Method transfer case study for instrument and LC column migration of the purification and analysis workflow for synthetic oligonucleotides
LCMS
Method transfer case study for instrument and LC column migration of the purification and analysis workflow for synthetic oligonucleotides
Sample Preparation, HPLC, Consumables, LC columns, LC/MS, LC/MS/MS, LC/Orbitrap, LC/HRMS
Instrumentation
Sample Preparation, HPLC, Consumables, LC columns, LC/MS, LC/MS/MS, LC/Orbitrap, LC/HRMS
Manufacturer
Thermo Fisher Scientific
Industries
Pharma & Biopharma
Open paper High-sensitive multi-attribute analysis of ADCs under native conditions by using an online multiple heart-cut 2D-LC-HRAM mass spectrometry system
LCMS
High-sensitive multi-attribute analysis of ADCs under native conditions by using an online multiple heart-cut 2D-LC-HRAM mass spectrometry system
2D-LC, LC/MS, LC/MS/MS, LC/Orbitrap, LC/HRMS, GPC/SEC
Instrumentation
2D-LC, LC/MS, LC/MS/MS, LC/Orbitrap, LC/HRMS, GPC/SEC
Manufacturer
Thermo Fisher Scientific
Industries
Pharma & Biopharma
Open paper Green ion pair and HFIP free method for ASO RNA analysis with GLP compliant automated data handling
LCMS
Green ion pair and HFIP free method for ASO RNA analysis with GLP compliant automated data handling
LC/MS, LC/MS/MS, LC/Orbitrap, LC/HRMS
Instrumentation
LC/MS, LC/MS/MS, LC/Orbitrap, LC/HRMS
Manufacturer
Thermo Fisher Scientific
Industries
Pharma & Biopharma
Open paper Detailed study into ASO impurity analysis, lessons learned, and myths dispelled while moving to compliant platform methods
LCMS
Detailed study into ASO impurity analysis, lessons learned, and myths dispelled while moving to compliant platform methods
LC/MS, LC/MS/MS, LC/Orbitrap, LC/HRMS
Instrumentation
LC/MS, LC/MS/MS, LC/Orbitrap, LC/HRMS
Manufacturer
Thermo Fisher Scientific
Industries
Pharma & Biopharma
Open paper Performance evaluation of a new reversed-phase column for peptide mapping and monitoring of monoclonal antibodies
LCMS
Performance evaluation of a new reversed-phase column for peptide mapping and monitoring of monoclonal antibodies
Consumables, LC columns, LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap
Instrumentation
Consumables, LC columns, LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap
Manufacturer
Thermo Fisher Scientific
Industries
Pharma & Biopharma
Open paper A novel approach for multiple PQAs monitoring of mAbs from bioreactors using 2D-LC-MS
LCMS
A novel approach for multiple PQAs monitoring of mAbs from bioreactors using 2D-LC-MS
2D-LC, LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap
Instrumentation
2D-LC, LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap
Manufacturer
Thermo Fisher Scientific
Industries
Pharma & Biopharma
Open paper Comprehensive extractables analysis using novel automated parallel extraction and concentration coupled with a multi-detector LC/UV/CAD/HRAM Orbitrap MS system
LCMS
Comprehensive extractables analysis using novel automated parallel extraction and concentration coupled with a multi-detector LC/UV/CAD/HRAM Orbitrap MS system
Sample Preparation, HPLC, LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap
Instrumentation
Sample Preparation, HPLC, LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap
Manufacturer
Thermo Fisher Scientific
Industries
Pharma & Biopharma
