Waters | Wyatt Particle & Macromolecule Characterisation Forum: Advanced Analytics for Proteins and Nanoparticles using Light Scattering Techniques

Unlock deeper insights into proteins, peptides, nanoparticles, and complex therapeutic modalities at this one-day scientific forum dedicated to advanced characterisation technologies and applications.

Through expert presentations, practical case studies, and interactive discussions, you'll discover how light scattering and complementary analytical techniques can reveal critical information about molecular size, molar mass, aggregation, stability, and particle composition. Explore the latest approaches in SEC-MALS, FFF-MALS, DLS, CDMS, protein stability screening, nanoparticle analysis, and peptide and GLP-1 therapeutic characterisation.

Whether you're working with biologics, drug delivery systems, or next-generation therapeutics, the forum offers valuable guidance on method development, troubleshooting, and best practices, alongside opportunities to connect with peers and share experiences tackling similar analytical challenges.

Designed for scientists involved in the development, characterisation, and quality assessment of complex molecular systems, this event presents an exciting opportunity to learn, connect, and inspire future collaboration and growth.

Register now!

AGENDA

09:00   Registration and Breakfast

09:20 Welcome and Introduction

09:30 From Fundamentals to Confidence: Quality Assessment by Light Scattering: An Overview and New Developments

09:50  Biophysical Stability: High-throughput Protein Stability Screening: Aggregation, kD, A2, Tagg

10:20 Break

10:50 Guest Presentation - TBA

11:25 SEC-MALS for Complex Therapeutics: Characterisation of Protein Oligomers and Conjugates, including ADCs and AOCs

11:50 Multi-Attribute Quantification of Nanoparticle Drug Delivery Systems: Mass, Aggregation, Free RNA, Capsid Integrity, Capsid Ratio, and Titre in a Single Experiment

12:10 Lunch

13:20 Characterising Large or Challenging Proteins and Nanoparticles: Field-Flow Fractionation when Size-exclusion Chromatography is not enough

13:45 Guest Presentation - TBA

14.15 Transforming Peptide Characterisation: SEC and Complementary Chromatography for Peptides and GLP-1 Therapeutics

14:35 Beyond Light Scattering - Solutions for Large Molecules: CDMS for Very Large Biomolecules, plus Aura Particle Detection and Identification

15:00 Break

15:30 Getting the most from SEC-MALS, FFF-MALS and DLS: Best Practice and Troubleshooting Strategies

15:50 Method Setup for SEC-MALS, FFF-MALS and DLS: Practical Guidance for Method Development - Waters

16:10 Closing Discussion

16:30 Close

Where?

• Austin Court: An Institute of Engineering & Technology Venue
• 80 Cambridge Street, Birmingham, WMD B1 2NP
• United Kingdom