Bruker at HUPO 2026

Functional Proteomics 2.0: From Biosamples to Bioinsights 

Meet Bruker at HUPO, Suntec Singapore Convention & Exhibition Centre, September 27 - October 1, and see how next-generation mass spectrometry is transforming 4D Multiomics and Functional Proteomics 2.0. Explore the latest innovations across our portfolio, including timsUltra AIP, timsOmni™,  timsMetabo™, and more.

Join us throughout the week:

• Monday Lunch Seminar
  • “Functional Proteomics 2.0: Molecular Pathology, Spatial Context, and Functional Proteoforms”
  • Join us on Monday, September 28 at 12:15 for an engaging lunch seminar where you can enjoy a meal while exploring the latest advances in functional proteomics. Discover how advances in proteoform characterization, molecular pathology, and spatial proteomics are revealing a more complete and functional view of disease biology.
• Tuesday Lunch Seminar
  • “Functional Proteomics 2.0: Reading Disease Signals Across the Immune and Circulating Proteome”
  • Join us on Tuesday, September 29 at 12:15 for our Lunch Seminar and learn how cutting-edge immunopeptidomics and biofluid proteomics workflows are uncovering disease mechanisms, actionable biomarkers, and new opportunities for precision medicine.
• Visit our team at booth 120 to connect with our experts, learn more about our latest technologies, and see how Bruker solutions are enabling new levels of insight across a wide range of research applications.

Register here

Functional Proteomics 2.0: Molecular Pathology, Spatial Context, and Functional Proteoforms

Genomics tells us what could happen. Proteomics shows what is happening.

This session brings together cutting-edge advances in deep proteoform characterization, clinical proteomics implementation, and spatial tissue proteomics to address a core challenge: translating molecular measurements into biological and clinical insight. Our speakers will demonstrate how ion mobility-enabled workflows and multi-modal fragmentation strategies resolve proteoforms with unprecedented depth, exposing functional diversity hidden in traditional workflows. At the same time, real-world integration of proteomics into molecular pathology pipelines highlights what it takes to move from promise to routine application, particularly in complex tissue and disease types. Complementing this, emerging high-throughput spatial proteomics approaches are scaling tissue analysis while preserving biological context.

Together, these advances redefine what “functional proteomics” means: not just measuring proteins, but linking molecular form, spatial organization, and disease biology. The outcome is a more complete, mechanistic view of biology.

Featured presentations:

Deep proteoform analysis by ion mobility spectrometry and multi-modal tandem mass spectrometry

• Ole Nørregaard Jensen, Ph.D., Professor, Department of Biochemistry and Molecular Biology, University of Southern Denmark, Odense, Denmark

From potential to practice – implementing proteomics in molecular pathology

• Prof. Dr. med. Stephan Singer, Deputy Medical Director at the Institute of Pathology and Neuropathology, University of Tübingen, Germany

Scaling up and democratizing spatial tissue proteomics

• Fabian Coscia, Ph.D., Group Leader, Spatial Proteomics Group, Max Delbrück Center, Berlin, Germany

Event details:

• Date: Monday, September 28, 2026
• Time: 12:15 - 13:15
• Location: Suntec Singapore Convention & Exhibition Centre

Functional Proteomics 2.0: Reading Disease Signals Across the Immune and Circulating Proteome

Disease biology ultimately plays out at the protein level, across immune interfaces and circulating systems.

This session focuses on how proteomics is decoding functional disease signals in immunopeptidomes and biofluids, bridging the gap between molecular detection and clinical relevance. From ultra-deep immunopeptidomics, enabling sensitive discovery of antigen repertoires directly presented by cells, to high-precision biofluid proteomics, revealing early risk signatures and systemic disease states, our speakers will showcase how 4D-Proteomics™ workflows capture biology that remains invisible to genomics and transcriptomics alone.

Applications span autoimmunity, oncology, and neonatal disease, highlighting how protein-level measurements can stratify risk, uncover mechanisms, and define actionable biomarkers. By interrogating both immune presentation and circulating proteomes, this session demonstrates how proteins provide a direct, functional readout of disease processes, and why they are essential for the next generation of biomarkers and precision medicine.

Featured presentations:

Ultra-Deep Antigen Discovery: Immunopeptidomics on the timsUltra AIP

• Anthony Purcell, Ph.D., Professor, Biochemistry & Molecular Biology, Monash University, Melbourne, Australia 

What the Proteome Knows: Islet Autoimmunity Risk Revealed by diaPASEF Biofluid Proteomics

• Laura Gianni, Ph.D., Head, Proteomics Laboratory, Walter and Eliza Hall Institute of Medical Research (WEHI), Parkville, Australia

Serum Proteomics Profiling in Newborns: Differences Compared to Adults serum and new molecular panel for neonatal Sepsis

• Chiara Guerrera, Ph.D., IRHC, HDR, Head of Necker Proteomics, Faculty of Medicine, University Paris Cité, France
• Sara Ceccacci, Ph.D., Postdoc, Necker Proteomics and Imagine Institute Genetic Skin Disease Laboratory, Paris, France

Event details:

• Date: Tuesday, September 29, 2026
• Time: 12:15 - 13:15
• Location: Suntec Singapore Convention & Exhibition Centre