<p><strong>Our Library never stops expanding. What are the most recent contributions to LabRulezLCMS Library in the week of 2nd February 2026? Check out new documents from the field of liquid phase, especially HPLC and LC/MS techniques!</strong></p><blockquote><p><span style="font-size:20px;">👉 </span><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/library"><span style="font-size:20px;"><strong>SEARCH THE LARGEST REPOSITORY OF DOCUMENTS ABOUT LCMS AND RELATED TECHNIQUES</strong></span></a></p></blockquote><blockquote><p><strong>👉 Need info about different analytical techniques?</strong> Peek into <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library"><strong>LabRulezGCMS</strong></a> or <a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/library"><strong>LabRulezICPMS</strong></a> libraries.</p></blockquote><p>This week we bring you application notes by <strong>Agilent Technologies </strong>and<strong> Waters Corporation, </strong>technical note by<strong> Shimadzu </strong>and poster by <strong>Thermo Fisher Scientific / MSACL!</strong></p><h3><strong>1. Agilent Technologies: Quantitative Separation of THC Isomers and Metabolites from Whole Blood</strong></h3><p><strong>Using Agilent Captiva Enhanced Matrix Removal (EMR) cartridges and LC/MS/MS</strong></p><ul><li>Application note</li><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/an_thc_isomers_captiva_emr_lctq_5994_8664en_agilent_5eb50dc6f9.pdf"><strong>Full PDF for download</strong></a></li></ul><p>THC isomers (Δ8- and Δ9-THC, in particular) are psychoactive compounds of increasing interest in forensic toxicology, where accurate identification and quantification of these individual isomers and their respective metabolites are essential for legal and clinical assessments. However, an analytical challenge derives from their structural or empirical similarity and the presence of potential isobaric interferences.&nbsp;</p><p>Isobaric compounds are molecules that are empirically identical, share the same nominal mass, but differ in structure. In the context of THC analysis, CBD and exo-THC are notable isobaric interferences. These compounds can coelute or produce overlapping mass spectral signals, complicating the interpretation of results. CBD, a nonpsychoactive cannabinoid, shares an identical molecular weight and similar fragmentation pattern with THC isomers, making it difficult to distinguish using conventional mass spectrometry alone. Exo-THC, another structural analog, further adds to the complexity for the same reasons.&nbsp;</p><p>Without adequate chromatographic separation, these isobaric interferences can lead to false positives or inaccurate quantitation. This is particularly problematic in forensic settings, where precise identification of psychoactive substances is critical. Therefore, a robust analytical method that can resolve these compounds and potential interferents is&nbsp;desirable.&nbsp;</p><p>This study introduces a workflow that combines enhanced matrix removal (EMR) with LC/MS/MS to achieve baseline separation of THC isomers and their metabolites from the isobaric interferences that were examined within the scope of this application note. The method enables confident separation, identification, and quantification in a single 15-minute analysis.</p><h4><strong>Experimental</strong></h4><h5><strong>Chromatographic separation and LC/MS/MS detection&nbsp;</strong></h5><p>This procedure can be accomplished using different instrument configurations. Chromatographic separation was verified using both an <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/library?mainauthorItems=10&amp;search=1260+Infinity+II+LC"><strong>Agilent 1260 Infinity II LC</strong></a> and an <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/library?mainauthorItems=10&amp;search=1290+Infinity+II+LC"><strong>Agilent&nbsp;1290 Infinity II LC</strong></a>. Analyte detection and quantitation were performed via both an <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/library?mainauthorItems=10&amp;search=6475"><strong>Agilent 6475 triple quadrupole LC/MS</strong></a> and an <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/library?mainauthorItems=10&amp;search=Ultivo"><strong>Agilent&nbsp;Ultivo triple quadrupole LC/MS</strong></a>. Method&nbsp;parameters are detailed in Tables 1 and 2. Detailed MRM transition settings are outlined in Appendix A.</p><h4><strong>Conclusion&nbsp;</strong></h4><p>This study presents an effective, integrated workflow for the separation and quantification of THC isomers and metabolites in whole blood. Agilent&nbsp;Captiva EMR–Lipid cartridges removed sufficient matrix interferences to enable clean extraction and high analyte recovery. Chromatographic separation using an Agilent InfinityLab Poroshell 120 PFP column provided reliable resolution of isobaric compounds, including CBD and exo-THC. Coupled with Agilent LC/MS/MS systems featuring Agilent Jet Stream ionization technology, the method delivered consistent sensitivity and selectivity across a complex panel of analytes. Together, this methodology offers the basis of a streamlined workflow for the separation of Δ8-, Δ9-, and Δ10-THC isomers and their respective hydroxy and carboxy metabolites and potential interferents from whole blood.</p><h3><strong>2. Shimadzu: Optimization of Supercritical Fluid Extraction Parameters for Vitamins D2, D3, and K1 from Pharmaceutical Preparations</strong></h3><ul><li>Technical note</li><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/c190_e333_6198eb84b9.pdf"><strong>Full PDF for download</strong></a></li></ul><p>Vitamins are organic compounds, essential in small amount, crucial for the normal functioning of the human body, facilitating numerous enzymatic and metabolic functions[1]. Since the human organism cannot produce vitamins, the diet represents the main route of ingestion of these compounds. As consumer awareness grows, reliable information about the vitamin content in foods is becoming a critical issue. However, considering that vitamins could be losses during food processing and storage, the readyto-use multi-vitamin pharmaceutical preparations are becoming widely employed among consumers. These facts, together with the introduction of labelling regulations, introduced the need for ensure the quality control of these types of formulation.</p><h4><strong>2. Experimental</strong></h4><h5><strong>2.3 Instrumentation</strong></h5><p>The supercritical fluid extraction (SFE) was carried out by using a SFE pretreatment system (<a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/library?mainauthorItems=1&amp;search=Nexera+UC"><strong>Shimadzu Nexera UC</strong></a>) equipped with: a CBM-40 controller, an SFE-30A module, an LC-30ADSF CO2 pump, an LC-40D XR modifier pump, an LC-40D make-up pump, an SFC-30A back pressure regulator, a DGU-40 on-line degasser, an FRC-40 fraction collector. A combination of static and dynamic extraction was employed (Figure 2).</p><h4><strong>Conclusion&nbsp;</strong></h4><p>Considering the obtained results, the vitamins extraction revealed as strictly matrix dependent, according to the formulation excipients. Therefore, detailed study needs to be performed to better understand the vitamin formulation.</p><h3><strong>3. Thermo Fisher Scientific / MSACL: Simultaneous quantitation and discovery (SQUAD) of fecal bile acids and their conjugates in children with autism spectrum disorder (ASD)</strong></h3><ul><li>Poster</li><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/po_squad_fecal_bile_acids_children_asd_po_en_af787058d3.pdf"><strong>Full PDF for download</strong></a></li></ul><p>This study presents a <strong>Simultaneous Quantitation and Discovery (SQUAD)</strong> metabolomics workflow applied to the analysis of <strong>fecal bile acids and their microbial conjugates</strong> in children with <strong>Autism Spectrum Disorder (ASD)</strong> undergoing <strong>microbiota transfer therapy (MTT)</strong>. Bile acids play a key role in lipid metabolism and gut–brain signaling, and alterations in gut microbiota composition in ASD have been linked to disrupted bile acid metabolism. The SQUAD approach was designed to address the need for both <strong>targeted quantification</strong> of known bile acids and <strong>untargeted discovery</strong> of novel metabolic features within a single LC–MS injection.</p><p>The workflow integrates <strong>reversed-phase liquid chromatography</strong> with advanced mass spectrometry using a <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/748"><strong>Thermo Scientific Orbitrap Ascend Tribrid mass spectrometer</strong></a> coupled to a <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/744"><strong>Thermo Scientific Vanquish Horizon UHPLC system</strong></a>. Quantitative analysis was performed using <strong>parallel reaction monitoring (PRM)</strong> in the <strong>linear ion trap</strong>, while <strong>high-resolution MS¹ scanning in the Orbitrap</strong> enabled confident metabolite annotation. The Tribrid architecture—combining a quadrupole, linear ion trap, and Orbitrap—allowed high selectivity and sensitivity, including MSⁿ capabilities for resolving <strong>co-eluting structural isomers</strong> such as leucine- and isoleucine-conjugated bile acids.</p><p>Using calibrated bile acid standards, the method achieved <strong>absolute quantitation across six orders of magnitude</strong>, with limits of quantitation below <strong>1.8 femtomoles on column</strong>. The SQUAD workflow was applied to fecal samples collected before and after MTT, revealing <strong>distinct shifts in bile acid and lipid-related metabolite profiles</strong> following treatment. Multivariate analysis, including <strong>principal component analysis (PCA)</strong>, demonstrated clear separation between pre- and post-treatment samples in the MTT group, while no comparable changes were observed in placebo controls.</p><p>Overall, the results demonstrate that SQUAD metabolomics enables <strong>high-throughput, highly sensitive, and information-rich analysis</strong> by combining quantitative rigor with deep metabolic coverage in a single experiment. This integrated LC–MS workflow provides valuable insight into the biochemical effects of microbiome modulation in ASD and highlights the power of <strong>Orbitrap Tribrid–based metabolomics</strong> for studying complex host–microbiome interactions in clinical research.</p><h3><strong>4. Waters Corporation: Analysis of Organic Carbonates in Lithium- Ion Battery Electrolyte by High-Performance Liquid Chromatography (HPLC) with Mass Detection (MS)</strong></h3><ul><li>Application note</li><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/720009211_en_46cbebda90.pdf"><strong>Full PDF for download</strong></a></li></ul><h5><strong>Benefits&nbsp;</strong></h5><ul><li>Sensitive method for low-level detection and quantification of carbonate solvents (0.05–1 ppm) and carbonate-based aging products (0.00075–0.0025 ppm) in lithium-ion battery electrolyte solutions using the ACQUITY QDa II Mass Detector with SIR acquisition mode.</li><li>Robust chromatographic separation using the XSelect Premier HSS PFP Column under 7 minutes analysis time, operated under reversed-phase conditions.</li></ul><p>The electrolyte is one of the main components in the lithium-ion battery.<sup>1,2</sup> It is a conductive solution that transports lithium ions from the cathode to the anode during the charging process. During discharge, the lithium ions flow from the anode to the cathode. The electrolyte solution is composed of lithium salt dissolved in a mixture of organic solvents.<sup>1,2</sup> The organic solvents are typically a mixture of cyclic and linear carbonates, including EC, PC, DMC, EMC, and DEC.<sup>2</sup> Lithium hexafluorophosphate (LiPF<sub>₆</sub>) is commonly used as the conducting lithium salt,<sup>2</sup> providing the necessary ionic conductivity for efficient battery operation.&nbsp;</p><p>The LiPF6 salt in carbonate-based systems can exhibit chemical and thermal instability, which can impact the performance of the lithium-ion batteries.<sup>2-4</sup> Electrolyte solutions can also degrade, forming aging products including DMDOHC and DEDOHC.<sup>2</sup> Various techniques are employed to investigate quality and properties of the electrolytes. Techniques such as scanning calorimetry (DSC) and thermogravimetric analysis (TGA) offer a comprehensive analysis of an electrolyte’s thermal properties, while rheology measures viscosity of the conductivity solutions.<sup>1</sup> Additionally, chromatographic methods are used to measure the quantity of carbonate solvents in electrolyte solutions.<sup>2-4</sup> Gas chromatography mass spectrometry (GC/MS) and liquid chromatography mass spectrometry (LC/MS) are common techniques used to investigate carbonate-based electrolytes.<sup>3</sup>&nbsp;</p><p>In this application note, an HPLC method with mass detection was developed for the analysis of five common carbonate solvents and two carbonate-based aging products (Table 1). The method employed an ACQUITY QDa II Mass Detector coupled with an Arc Premier System. Method performance characteristics including limit of detection (LOD), limit of quantification (LOQ), linearity and system suitability were demonstrated. Additionally, the developed method was applied for the analysis of LiPF<sub>6</sub><sup>-</sup>based electrolyte solution.</p><h4><strong>Experimental</strong></h4><h5><strong>Method Conditions&nbsp;</strong></h5><ul><li><strong>System: </strong><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/306"><strong>Arc Premier System</strong></a>, Column Manager with active pre-heating, PDA and the ACQUITY QDa II Mass Detector&nbsp;</li><li><strong>Column: </strong>XSelect Premier HSS PFP Column, 2.5 µm, 4.6 mm x 100 mm (Waters, p/n: 186010051)</li><li><strong>MS system: </strong><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/1543"><strong>ACQUITY QDa II Mass Detector</strong></a></li></ul><h5><strong>Data Management&nbsp;</strong></h5><ul><li><strong>Chromatography data software (CDS): </strong><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/627"><strong>Empower™ 3.6.1</strong></a></li></ul><h4><strong>Results and Discussion&nbsp;</strong></h4><p>Chromatographic columns with a wide range of selectivity were explored during this study to ensure separation between carbonate solvents and carbonate-based aging products. The selected columns (XSelect Premier CSH™ C18, XSelect Premier CSH Phenyl Hexyl, XSelect Premier HSS T3, XSelect Premier HSS PFP) were tested with acetonitrile and methanol solvents. The study showed that XSelect Premier HSS PFP Column with methanol provided the best retentivity and separation for all analytes (Figure 1). The method successfully separated carbonate solutions and carbonate-based aging products in less than a 7-minute gradient time. The MS total ion chromatogram (TIC) data was collected across the mass range of 35–300 Da using electrospray ionization in positive (ESI+) mode (Figure 1A). The mass spectral data facilitated quick and accurate identification of the components. The carbonate solvents formed [M + H]+ molecular ions, while the selected aging products formed sodium adducts, [M + Na]+. These ions were measured using a selected ion recording (SIR) acquisition mode, which determines intensity for a single ion of interest (Figure 1B).</p><h4><strong>Conclusion&nbsp;</strong></h4><p>A sensitive and reliable HPLC-MS method using the Arc Premier System coupled with the ACQUITY QDa II Mass Detector was developed for the analysis of carbonate solvents and carbonate-based aging products in lithium-ion battery electrolyte. This reversed-phase LC method successfully separated all five carbonate solvents (EC, PC, DMC, EMC, DEC) and two aging products (DMDOHC/DEDOHC) on an XSelect Premier HSS PFP Column. Low-level quantification limits were achieved using SIR acquisition mode ranging from 0.05 to 1 ppm and 0.00075–0.0025 ppm for carbonate solvents and aging products, respectively. The method was demonstrated to be applicable for the analysis of lithium-ion battery electrolyte.</p>

News from LabRulezLCMS Library - Week 06, 2026

News from LabRulezLCMS Library - Week 20, 2026

<p><strong>In September 2026, Prague will become a global meeting point for the chromatography community. From 6 to 10 September 2026, the city will host the </strong><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/events/644"><strong>35th International Symposium on Chromatography – ISC 2026</strong></a><strong>, one of the leading international events dedicated to chromatography, separation science, and analytical chemistry.</strong></p><p><strong>Shimadzu</strong> is proud to support this prestigious event as a <strong>Platinum Sponsor</strong>.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/ISC_2026_Shimadzu_as_a_platinum_sponsor_mensi_8c9f3eb6e7.jpg" alt="ISC 2026: Platinum sponsor Shimadzu" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_ISC_2026_Shimadzu_as_a_platinum_sponsor_mensi_8c9f3eb6e7.jpg 235w," sizes="100vw" width="1600" height="1066"></p><p>ISC 2026 represents a unique opportunity for scientists, researchers, industry experts, application specialists, and technology providers to meet, exchange knowledge, and discuss the latest developments in chromatography and separation science. The conference will bring together experts from academia, pharmaceutical industry, environmental analysis, food safety, healthcare, life sciences, and many other fields where analytical technologies play an essential role.</p><p>We would like to warmly invite our <strong>customers, partners, colleagues</strong>, and the wider <strong>scientific community</strong> to join us at ISC 2026 in Prague. The conference will offer an inspiring scientific programme, lectures by internationally recognised experts, dedicated sessions on current trends and challenges, an exhibition area, and valuable opportunities for networking with the global chromatography community.</p><p>Following the successful <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/events/642"><strong>ISC 2024 in Liverpool</strong></a>, ISC 2026 will bring this important international symposium to the heart of Europe. We are looking forward to meeting you in Prague and contributing together to a strong and successful edition of ISC.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/1728218963766_9d5394a9da.jpg" alt="Gesa Schad: Shimadzu at ISC 2024 in Liverpool" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_1728218963766_9d5394a9da.jpg 156w," sizes="100vw" width="1280" height="1280"></p><p><strong>Visit </strong><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/events/1371"><strong>Shimadzu at ISC 2026</strong></a><strong> in Prague and be part of one of the key international events in chromatography and separation science.</strong></p><blockquote><p class="cke-user_style-important">Registration is open on the official conference website:<br><a target="_blank" rel="noopener noreferrer" href="https://www.isc2026.org"><strong>www.isc2026.org</strong></a></p></blockquote><h3><strong>Shimadzu Vendor Seminar: Three New Reasons to Rethink Your Workflow</strong></h3><ul><li>07 September 2026</li><li>12 PM - &nbsp;13 PM</li></ul><p>Join us for an engaging seminar introducing three new analytical solutions designed to help laboratories work smarter, respond faster, improve robustness, and achieve greater confidence in their results. As analytical demands continue to grow, laboratories need technologies that not only deliver strong performance, but also enhance efficiency, flexibility, and ease of operation. This seminar will highlight how our <strong>latest innovations in IC, UHPLC, and GC-MS/MS</strong> can streamline workflows, support complex applications, and create new opportunities for productivity across your laboratory.</p><h5><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/library?mainauthorItems=1&amp;search=nexera+ic"><strong>Nexera IC</strong></a><strong> – New compact ion chromatography solution for reliable, high-sensitivity anion and cation analysis.</strong></h5><ul><li>Dr. Gesa Schad</li></ul><h5><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/library?mainauthorItems=1&amp;search=nexera+x4"><strong>Nexera X4</strong></a><strong> – Next-generation UHPLC platform designed for ultra-high performance and robust operation without compromise.</strong></h5><ul><li>Dr. Gesa Schad</li></ul><h5><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/c146_e517_16e9bfd835.pdf"><strong>GCMS-TQ RX Series</strong></a><strong> – Advanced triple quadrupole GC-MS/MS systems engineered for enhanced sensitivity and dependable trace-level analysis.</strong></h5><ul><li>Dr. Waldemar Weber</li></ul><blockquote><p class="cke-user_style-important"><a target="_blank" rel="noopener noreferrer" href="https://www.shimadzu.eu/forms/vendor-seminar-registartion_isc2026.html"><strong>Register here</strong> <strong>to attend Shimadzu Vendor Seminar</strong></a></p></blockquote><h3><strong>Scientific Programme Presentation</strong></h3><ul><li>08 September 2026</li><li>10:30 – 12:00</li><li>Fun 5: Separations with Supercritical and Subcritical Fluids&nbsp;</li></ul><h5><strong>Accelerating Forensic Analysis: A Rapid SFC-MS Workflow for Novel Regioisomeric Fluorofentanyl Derivatives and Related Compounds</strong></h5><ul><li>Dr. Jennifer Field, Shimadzu UK, Milton Keynes, UK</li></ul><h3><strong>Winners of the Shimadzu student sponsorship</strong></h3><p>We are thrilled to announce the winners of the <strong>Shimadzu student sponsorship</strong> for <strong>free tickets to attend the ISC 2026</strong> conference. We received a great number of high-quality abstracts, showcasing the innovative research being conducted by students all over Europe.</p><p>We extend our heartfelt congratulations to all the winners and look forward to their contributions at the conference. To those who were not selected this time, we encourage you to continue your excellent work and apply again in the future.</p><p><strong>And the lucky winners are: &nbsp; &nbsp;</strong></p><h5><strong>Chromatography supports electrochemistry–mass spectrometry (EC-MS) analysis of olaparib and inavolisib metabolites</strong></h5><ul><li><strong>Fabiola Dontsi Tonleu</strong>, University of Münster, Germany&nbsp;</li><li><strong>Abstract ID:</strong> ISC-0262 &nbsp; &nbsp;</li></ul><h5><strong>Towards circular wind energy: Sample preparation strategies in combination with GC×GC-TOFMS for the characterization of wind turbine blade recycling products&nbsp;</strong></h5><ul><li><strong>Giulia Giacoppo</strong>, University of Ferrara, Italy</li><li><strong>Abstract ID:</strong> ISC-0169 &nbsp; &nbsp;</li></ul><h5><strong>Implementing SFC for analysis of antibiotics in manure</strong></h5><ul><li><strong>Michelle Hussock</strong>, University of Duisburg-Essen, Germany</li><li><strong>Abstract ID:</strong> ISC-0220 &nbsp;</li></ul><h5><strong>Identifying optimal LC-MS conditions for oligonucleotide mapping of mRNA: A multi-criteria assessment of methods</strong></h5><ul><li><strong>Athanasios Tsalmpouris</strong>, University of Geneva, Switzerland</li><li><strong>Abstract ID:</strong> ISC-0211</li></ul><h5><strong>From weeds to crop protectants: phytochemical profiling and dual biopesticidal activities of Chenopodium ambrosioides and Cleome gynandra &nbsp;</strong></h5><ul><li><strong>Rahim Ullah</strong>, University of Helsinki, Finland</li><li><strong>Abstract ID:</strong> ISC-0249 &nbsp;</li></ul><h4><strong>Poster Presentations</strong></h4><h5><strong>Optimal column selection for experimental surface polarity measurement using supercritical fluid chromatography</strong></h5><ul><li>Yoshiyuki Watabe, Shimadzu Corporation, Kyoto, Japan</li><li><strong>Session:</strong> BIO08 - Sample preparation and automation</li></ul><h5><strong>Characterization of SFC stationary phases for Analysis of Essential Oils</strong></h5><ul><li>Martin Meyer, Shimadzu Europa, Duisburg, Germany</li></ul><h5><strong>High-sensitivity analysis of more than 100 pesticides in food using microflow LC-MS/MS</strong></h5><ul><li>Ramy Abou Naccoul, Shimadzu France, Marne la Vallée, France</li><li><strong>Session:</strong> HYP05 - Microfluidic and chip separations in MS</li></ul><h5><strong>Streamlined selection of optimal separation conditions using an automated LC/SFC method development platform</strong></h5><ul><li>Dr. Gesa Schad, Shimadzu Europa, Duisburg, Germany</li><li><strong>Session: </strong>FUN05 - Separations with super - and sub-critical fluids</li></ul><h5><strong>Ion Chromatographic Determination of Major Inorganic Ions in Beer for Quality Control and Product Differentiation</strong></h5><ul><li>Dr. Vadim Kraft, Shimadzu Europa, Duisburg, Germany</li><li><strong>Session:</strong> FUN08 - Separation modes</li></ul><h5><strong>Efficient SFC Method Development for the Analysis of Essential Oils Using Shimadzu LabSolutions MD</strong></h5><ul><li>Dr. Brigitte Bollig, Shimadzu Europa, Duisburg, Germany</li><li><strong>Session:</strong> HYP02 - SFC-MS</li></ul><h5><strong>Assessing the applicability of retention modelling as a tool for oligonucleotide analysis using ion-pair HPLC</strong></h5><ul><li>Richard Hodgson, Shimadzu UK, Milton Keynes, UK</li></ul><h3><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/article/7477"><strong>ISC 2026 Scientific program</strong></a><strong> highlights</strong></h3><p>The programme runs across three parallel tracks — Fundamentals, Bioanalysis &amp; Omics Applications, and Hyphenation Techniques — covering topics from column technology, chiral and multi-dimensional separations, and AI/machine learning in separation science, to proteomics, green analytical chemistry, and LC/MS data processing.</p><h4><strong>Why it matters for industry</strong></h4><p>This year's Industry Program is shaping up particularly well, giving companies a direct space to connect with academia and the next generation of scientists:</p><ul><li><strong>Industry &amp; Education</strong> – bridging academic training with industry needs</li><li><strong>Career Presentation</strong> – companies showcase career paths and hiring needs to students and professionals</li><li><strong>AI in Separation Science </strong>– real-world use of AI in method development and lab workflows</li><li><strong>Sustainability in Separation Science</strong> – translating green chemistry research into industrial practice</li></ul>

Shimadzu to Join ISC 2026 in Prague as Platinum Sponsor

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Shimadzu Corporation is a global technology company founded in Kyoto, Japan, in 1875. Guided by its philosophy of “Contributing to Society through Science and Technology,” Shimadzu develops advanced analytical and measuring instruments, medical systems, industrial machinery, and other technologies supporting research, healthcare, industry, and society worldwide.

Shimadzu to Join ISC 2026 in Prague as Platinum Sponsor

News from LabRulezLCMS Library - Week 20, 2026

News from LabRulezLCMS Library - Week 06, 2026

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Waters Norway Clinical User Meeting

Waters at ISC 2026

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ADC characterization in one native LC-MS workflow

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