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Ion-Pairing Hydrophilic Interaction Chromatography for Impurity Profiling of Therapeutic Phosphorothioated Oligonucleotides
Ion-pairing HILIC improves impurity profiling of therapeutic oligonucleotides. It resolves deaminated impurities from full-length products, beyond current LC-MS limits.
Profiling of free fatty acids in wort using an isolator column-assisted LC-MS/MS approach
The study develops an LC-MS/MS method with isolator column and SPE for accurate FFA profiling in wort, aiming at improved efficiency and application in beer quality studies.
