Wiley, a global leader in authoritative content and research intelligence, today announced the release of additional data to its IR, Raman, LC-MS, and SmartSpectra libraries, significantly broadening compound coverage. The expansion brings Wiley's spectral database offerings to over 9.5 million high-quality spectra, delivering researchers enhanced capabilities for faster, more confident compound identification.“These updates deliver what researchers need most: broader coverage and greater confidence in their identifications,” said Graeme Whitley, senior director, Wiley Science Solutions. “By expanding our empirical collections, including updates to our renowned Sadtler IR and Raman libraries, alongside our SmartSpectra databases, we're providing quality data researchers can rely on to make critical decisions across their analytical workflows.”Subscribers automatically gain access to new data, ensuring labs always have the most current, reliable reference libraries to improve analysis, reduce errors, and increase productivity.<h4>KnowItAll Raman Spectral Library Collection</h4>The KnowItAll Raman collection has been expanded with 941 new spectra, bringing the total to more than 28,000 spectra. Two entirely new databases have been introduced: Raman – Drugs and Raman – Non-minerals.In addition, existing databases have been enriched with new content, including:<ul><li>600 spectra added to Raman – Sadtler Polymers &amp; Monomers (Basic 3)</li><li>200 spectra added to Raman – Minerals</li><li>16 spectra added to Raman – Polymers – Wiley</li></ul>These updates significantly strengthen Raman identification capabilities across polymers, minerals, and pharmaceutical compounds.<h4>KnowItAll IR Spectral Library Collection</h4>The KnowItAll IR collection has grown by more than 2,000 spectra, reaching a total of over 343,000 spectra. Three new databases have been added: IR – Contaminants, IR – Drugs, and IR – Polymers.An additional 100 spectra have also been incorporated into the IR – Minerals database, further expanding inorganic compound coverage.<h4>KnowItAll LC-MS Library Collection</h4>The KnowItAll LC-MS collection received one of the largest updates, with 497,000 new spectra added, representing an 18% increase. The collection now contains more than 3.2 million spectra.Seven new empirical LC-MS databases have been introduced, covering a broad range of application areas:<ul><li>LC-MS – Lipids Library</li><li>LC-MS – Pharmaceutical Compounds Library</li><li>LC-MS – Natural Products Library</li><li>LC-MS – Food Related Compounds Library</li><li>LC-MS – Environmental Compounds Library</li><li>LC-MS – General Compounds Library</li><li>LC-MS – Metabolites Library</li></ul>These additions greatly enhance support for untargeted screening, metabolomics, and complex mixture analysis.<h4>Wiley SmartSpectra IR Database Collection</h4>The SmartSpectra IR collection has nearly doubled in size with the addition of more than 249,000 spectra, bringing the total to over 499,000 spectra. Ten new databases have been added, covering critical compound classes such as lipids, endocrine disruptors, drugs, PFAS, pesticides, and additional emerging contaminants.<h4>Wiley SmartSpectra Raman Database Collection</h4>The SmartSpectra Raman collection experienced a major expansion, with over 100,000 new spectra added, representing a 300%+ increase. The collection now includes more than 133,000 spectra.Five new databases have been introduced, focusing on high-interest areas including lipids, PFAS, endocrine disruptors, cosmetics, and fragrances.<h4>Wiley SmartSpectra Vapor Phase IR Database Collection</h4>The SmartSpectra Vapor Phase IR collection has been expanded with more than 3,000 new spectra, increasing the total to over 218,000 spectra. Five new databases have been added, covering lipids, endocrine disruptors, fragrances, cosmetics, and PFAS—supporting improved analysis of volatile and semi-volatile compounds.By combining Wiley's empirical and SmartSpectra collections, researchers now have access to over 1 million IR spectra and over 161,000 Raman spectra—including the renowned Sadtler Libraries available exclusively through KnowItAll. SmartSpectra extends researchers' reach into chemical space beyond what's available in empirical libraries alone, enabling identification of compounds that haven't yet been physically measured.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Wiley_Wiley_adds_additional_data_to_its_Smart_Spectra_IR_Raman_and_LC_MS_libraries_2_35fae897f7.jpg" alt="Wiley: Wiley adds additional data to its SmartSpectra, IR, Raman, and LC-MS libraries" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Wiley_Wiley_adds_additional_data_to_its_Smart_Spectra_IR_Raman_and_LC_MS_libraries_2_35fae897f7.jpg 245w," sizes="100vw" width="1556" height="883">Wiley's comprehensive spectral database collections provide access to millions of high-quality spectra across a range of techniques, including IR, MS, NMR, Raman, and UV-Vis. These resources play a vital role in the interpretation, identification, verification, and classification of spectra across applications including pharmaceuticals, environmental science, forensics, materials research, and food safety.<blockquote><ul><li><a target="_blank" rel="noopener noreferrer" href="https://sciencesolutions.wiley.com/spectral-databases/">Learn more HERE</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://sciencesolutions.wiley.com/how-to-update-knowitall-databases">Current subscribers can ensure they are up to date</a></li></ul></blockquote><h4>About Wiley</h4>Wiley (NYSE: WLY) is a global leader in authoritative content and research intelligence for the advancement of scientific discovery, innovation, and learning. With more than 200 years at the center of the scholarly ecosystem, Wiley combines trusted publishing heritage with AI-powered platforms to transform how knowledge is discovered, accessed, and applied. From individual researchers and students to Fortune 500 R&amp;D teams, Wiley enables the transformation of scientific breakthroughs into real-world impact. From knowledge to impact—Wiley is redefining what's possible in science and learning. Visit us at <a target="_blank" rel="noopener noreferrer" href="https://www.wiley.com/en-ie/">Wiley.com</a>.

Wiley adds additional data to its SmartSpectra, IR, Raman, and LC-MS libraries

New edition of the Wiley Registry of Mass Spectral Data expands compound coverage to over 915,500 reference spectra, strengthening a foundational layer of Wiley’s scientific data and research intelligence portfolio.Wiley, a global leader in authoritative content and research intelligence for the advancement of scientific discovery, innovation and learning, today released the <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/products/887">Wiley Registry of Mass Spectral Data 2026</a>.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Wiley_Registry_of_Mass_Spectral_Data_2026_bc408d8245.jpg" alt="Wiley: Registry of Mass Spectral Data 2026" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Wiley_Registry_of_Mass_Spectral_Data_2026_bc408d8245.jpg 110w," sizes="100vw" width="1527" height="2162">As AI-driven research pipelines become standard practice across pharmaceuticals, materials science and forensic investigation, the quality of reference data underpinning those pipelines determines whether results are trusted—or stall at the verification stage.The Wiley Registry of Mass Spectral Data 2026 addresses this issue directly: One of the world’s largest and most trusted mass spectral reference databases for identifying unknown chemical compounds, it is now expanded and validated to meet the analytical demands of modern, AI-assisted laboratory workflows.Laboratories face increasingly complex analytical challenges—from detecting emerging environmental contaminants to identifying novel substances in forensic investigations. As a result, having access to a comprehensive, rigorously validated spectral database has become foundational to getting results right. It is also a critical validation layer for AI-driven workflows.The Wiley Registry database helps scientists and researchers around the world with environmental testing, forensic investigation, food safety research, drug analysis, defense research, homeland security, and more, providing critical reference data for identifying and analyzing chemical compounds and materials.The new edition represents a significant expansion of the collection, which now contains more than 915,500 reference spectra—the unique chemical “signatures” used to identify substances—making it among the most comprehensive databases of its kind. More than 42,000 new GC-MS spectra representing 34,100 compounds have been added, with data from laboratories, world patents and peer-reviewed scientific literature. Each spectrum is validated to the same rigorous standard, ensuring that the data perform reliably whether a researcher is running a manual comparison or feeding it into an automated identification pipeline.The Wiley Registry is part of Wiley’s growing portfolio of scientific data and research intelligence solutions, which includes spectral databases, chemistry and materials literature, and analytical tools designed to support researchers and organizations from discovery through to applied outcomes. Wiley spectral database solutions are trusted by the world’s top pharmaceutical companies and many Fortune 500 organizations—reflecting Wiley’s mission to transform knowledge into actionable intelligence, equipping researchers with the rigorous reference data that drives real-world scientific discovery.Updated every three years, the Wiley Registry is among the company’s longest-standing data products, with a history spanning decades of continuous development.“The Wiley Registry is a foundational layer of intelligence for any laboratory conducting GC-MS analysis—and increasingly, for the AI-assisted workflows being built around that analysis,” said Armughan Rafat, Wiley senior vice president and chief AI &amp; data analytics officer. “By expanding compound coverage and applying consistent quality measures across the collection, we help analysts provide a deterministic layer to move from unknown to identified faster.”Available in the most common instrumentation manufacturer formats, the Wiley Registry of Mass Spectral Data 2026 also offers bundled options to access even more data with its <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/products/885">Wiley Registry/NIST</a> and the KnowItAll GC-MS Library collection for labs seeking the most comprehensive coverage and workflow integration. The Wiley Registry is also available as a KnowItAll subscription for continued access to new data as they are added to the collection.Spectral databases contain detailed “fingerprints” of substances captured through analytical techniques such as <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/products/934">mass spectrometry (MS)</a> or <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/products/1271">Raman spectroscopy</a>, enabling researchers to identify unknown materials by comparing their spectral signatures against validated reference spectra. This data is essential for quality control, research verification and discovery across industries from pharmaceuticals to materials science.<blockquote>For more information about the Wiley Registry of Mass Spectral Data 2026, please <a target="_blank" rel="noopener noreferrer" href="https://sciencesolutions.wiley.com/solutions/technique/gc-ms/wiley-registry-of-mass-spectral-data/">visit this website</a>.</blockquote><h4>About Wiley</h4>Wiley (NYSE: WLY) is a global leader in authoritative content and research intelligence for the advancement of scientific discovery, innovation, and learning. With more than 200 years at the center of the scholarly ecosystem, Wiley combines trusted publishing heritage with AI-powered platforms to transform how knowledge is discovered, accessed, and applied. From individual researchers and students to Fortune 500 R&amp;D teams, Wiley enables the transformation of scientific breakthroughs into real-world impact. From knowledge to impact—Wiley is redefining what's possible in science and learning. Visit us at Wiley.com.

Wiley releases the 2026 edition of the Wiley Registry of Mass Spectral Data to expand GC-MS identification intelligence

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