Boosting Productivity in Toxicology Labs
LCMSArticle | Application

Boosting Productivity in Toxicology Labs

How do you boost toxicology productivity without sacrificing sensitivity? LC-MS/MS workflows enable rapid analysis of a broad range of drugs in 5–7 minutes.
Boosting Productivity in Toxicology Labs
Unlock High-Performance LC-MS with Factory-Certified Systems from Thermo Fisher Scientific
LCMSArticle | Product

Unlock High-Performance LC-MS with Factory-Certified Systems from Thermo Fisher Scientific

Get legendary Thermo Scientific LC-MS performance at a fraction of the cost. Factory-certified pre-owned systems deliver reliability, full warranty, expert support, and a smarter, sustainable investment.
Unlock High-Performance LC-MS with Factory-Certified Systems from Thermo Fisher Scientific
Unlocking Phytoplankton Metallomes with Comparative Analysis of Metal Quotas, Quantitative Proteomics, and Inferred Metalloproteomes
ICPMSLCMSScientific article | Science and research

Unlocking Phytoplankton Metallomes with Comparative Analysis of Metal Quotas, Quantitative Proteomics, and Inferred Metalloproteomes

This study integrates metal quotas, quantitative proteomics, and inferred metalloproteomes to reveal trace metal requirements and adaptation strategies in phytoplankton.
Unlocking Phytoplankton Metallomes with Comparative Analysis of Metal Quotas, Quantitative Proteomics, and Inferred Metalloproteomes
Reduce Sample Waste in the Lab Using Real-Time Data Evaluation with Automated Reactions
LCMSArticle | Software

Reduce Sample Waste in the Lab Using Real-Time Data Evaluation with Automated Reactions

Reduce sample waste and prevent data loss in LC-MS analysis using real-time data evaluation with system suitability testing and intelligent run control in Chromeleon software.
Reduce Sample Waste in the Lab Using Real-Time Data Evaluation with Automated Reactions
Hydrophilic Interaction Chromatography HRMS with Acrylamide Monolithic Columns: A Novel Approach for Intact Antibody Glycoform Characterization
LCMSScientific article | Science and research

Hydrophilic Interaction Chromatography HRMS with Acrylamide Monolithic Columns: A Novel Approach for Intact Antibody Glycoform Characterization

This study introduces acrylamide monolith HILIC-MS for intact mAb glycoprofiling, offering high selectivity, baseline separation, and detection of low-abundance glycoforms missed by RPLC-MS.
Hydrophilic Interaction Chromatography HRMS with Acrylamide Monolithic Columns: A Novel Approach for Intact Antibody Glycoform Characterization
Collision-Based Ion-activation and Dissociation
LCMSArticle | Academy

Collision-Based Ion-activation and Dissociation

Collision-based ion activation, developed nearly 80 years ago, remains the most widely used fragmentation method. Learn about three key techniques on Thermo Scientific MS.
Collision-Based Ion-activation and Dissociation
Ion-Pairing Hydrophilic Interaction Chromatography for Impurity Profiling of Therapeutic Phosphorothioated Oligonucleotides
LCMSScientific article | Science and research

Ion-Pairing Hydrophilic Interaction Chromatography for Impurity Profiling of Therapeutic Phosphorothioated Oligonucleotides

Ion-pairing HILIC improves impurity profiling of therapeutic oligonucleotides. It resolves deaminated impurities from full-length products, beyond current LC-MS limits.
Ion-Pairing Hydrophilic Interaction Chromatography for Impurity Profiling of Therapeutic Phosphorothioated Oligonucleotides
Development and thorough evaluation of a multi-omics sample preparation workflow for comprehensive LC-MS/MS-based metabolomics, lipidomics and proteomics datasets
LCMSScientific article | Science and research

Development and thorough evaluation of a multi-omics sample preparation workflow for comprehensive LC-MS/MS-based metabolomics, lipidomics and proteomics datasets

This study aimed to develop and compare ten extraction protocols to find the most effective method for generating metabolomics, lipidomics, and proteomics data from postmortem tissue.
Development and thorough evaluation of a multi-omics sample preparation workflow for comprehensive LC-MS/MS-based metabolomics, lipidomics and proteomics datasets
Mucinomics: The Next Frontier of Mass Spectrometry
LCMSArticle | Science and research

Mucinomics: The Next Frontier of Mass Spectrometry

Dr. Stacy Malaker shared advances in mucin characterization, enrichment, and their role in disease research during a Nature webinar. Here are the key takeaways.
Mucinomics: The Next Frontier of Mass Spectrometry
Metabolomics of Withania somnifera L. extracts by an integrated LC-MS and NMR approach and evaluation of their tyrosinase inhibitory activity
ICPMSLCMSScientific article | Science and research

Metabolomics of Withania somnifera L. extracts by an integrated LC-MS and NMR approach and evaluation of their tyrosinase inhibitory activity

This study analyzed Withania somnifera extracts from various eco-friendly methods using LC-MS/NMR, and evaluated their metabolite profiles and tyrosinase inhibitory activity.
Metabolomics of Withania somnifera L. extracts by an integrated LC-MS and NMR approach and evaluation of their tyrosinase inhibitory activity