<p><strong>Dear Customers, Partners, and Friends,</strong></p><p>As we approach the end of another productive year, I would like to extend my sincere thanks to all of you for your continued trust, collaboration, and support. This has been a year of meaningful growth for our company, and none of it would have been possible without the strong relationships we share with you.</p><p>Over the past twelve months, we have significantly expanded our portfolio of supported instruments, strengthening Clarity’s position as a flexible and reliable chromatography data solution. We also successfully released several new Clarity upgrades, each shaped by your feedback and by our commitment to continuous improvement, system stability, and new functionality.</p><p>We are grateful for the many messages we received from you throughout the year. Your insights and experiences directly influence our development priorities, motivating us to raise the bar continually. To support you even better, we have expanded our team by hiring new colleagues in technical support, ensuring faster responses, broader expertise, and a more personal approach.</p><p>As we look ahead, we remain committed to enhancing our products, strengthening our partnerships, and working closely with you to achieve your goals. Thank you for being an essential part of our story this year. On behalf of our entire team, I wish you a wonderful holiday season and a successful new year. We look forward to continuing our cooperation in 2026.</p><p><strong>Warm regards,</strong></p><p><strong>Jan Hruby</strong><br><strong>General Manager</strong></p><blockquote><p><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/article/2743"><strong>Jan Hruby: Supporting Chromatography Everywhere – Even Mars</strong></a></p></blockquote>

Season’s Greetings from DataApex

<h3><strong>Introduction</strong></h3><p><strong>This article provides a detailed, structured explanation of the Instrument Window in </strong><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/999"><strong>Clarity Chromatography Software</strong></a><strong>, as demonstrated in the referenced video tutorial. The Instrument Window is the central operational interface used for method setup, acquisition control, monitoring, data evaluation, and calibration.</strong></p><h3><strong>General Layout of the Instrument Window</strong></h3><p>The Instrument Window is divided into <strong>three main sections</strong>, each serving a distinct role in the chromatographic workflow:</p><ol><li><strong>Simplified Workflow Icons</strong></li><li><strong>Analysis Status and Acquisition Control Bar</strong></li><li><strong>Information Table for the Running Analysis</strong></li></ol><p>Together, these sections provide a streamlined overview of the entire analytical process—from method configuration to data processing.</p><h3><strong>Section 1: Simplified Workflow Icons</strong></h3><p>The upper portion of the Instrument Window contains a series of icons representing a simplified, logical chromatographic workflow. Each icon opens a dedicated dialog or window related to a specific step of the analysis.</p><h4><strong>Method Setup</strong></h4><ul><li>Opens the <strong>Method Setup dialog</strong></li><li>Allows users to browse through multiple configuration tabs</li><li>Used to define all parameters required for measurement (instrument settings, detector configuration, timing, etc.)</li></ul><p>This is the primary starting point for defining how an analysis will be performed.</p><h4><strong>Single Analysis and Sequence Setup</strong></h4><ul><li>Provides access to <strong>Single Analysis</strong> and <strong>Sequence</strong> dialogs</li><li>Enables configuration of:<ul><li>Individual measurements</li><li>Automated sequences consisting of multiple samples</li></ul></li></ul><p>These dialogs are used to define what will be measured and in what order.</p><h4><strong>Device Monitor</strong></h4><ul><li>Displays a <strong>dedicated section for each configured instrument</strong></li><li>Shows the <strong>current operational state</strong> of instruments</li><li>Allows real-time supervision of system readiness and status</li></ul><p>This function is essential for verifying that all hardware components are correctly configured and operational.</p><h4><strong>Data Acquisition (Signal Monitoring)</strong></h4><ul><li>Opens the <strong>Data Acquisition dialog</strong></li><li>Enables <strong>real-time monitoring of detector signals</strong></li><li>Allows users to observe live chromatographic responses during analysis</li></ul><p>This feature is particularly useful during method development, troubleshooting, or system verification.</p><h4><strong>Chromatogram Window</strong></h4><ul><li>Provides access to measured chromatograms</li><li>Used for:<ul><li>Viewing chromatographic data</li><li>Evaluating peak shapes and retention times</li><li>Performing data interpretation tasks</li></ul></li></ul><p>This is the primary environment for post-acquisition data review.</p><h4><strong>Calibration</strong></h4><ul><li>Opens the <strong>Calibration Window</strong></li><li>Used to set up and manage calibrations</li><li>Supports quantitative evaluation by linking signal response to concentration</li></ul><p>Calibration is a critical step for ensuring accurate and reproducible quantitative results.</p><h3><strong>Section 2: Analysis Status and Acquisition Control</strong></h3><p>The second major section of the Instrument Window is the <strong>Analysis Status Bar</strong>, which provides immediate feedback on the system and analysis state.</p><h4><strong>Key Functions</strong></h4><ul><li>Displays the <strong>current status of the instrument</strong></li><li>Shows whether the system is idle, running, or in another operational state</li><li>Contains <strong>acquisition control buttons</strong> to:<ul><li>Start analyses</li><li>Stop or control data acquisition</li></ul></li></ul><p>This section acts as the operational control center during routine work.</p><h3><strong>Section 3: Information Table</strong></h3><p>The third section is an <strong>Information Table</strong> that displays details about the currently running analysis.</p><h4><strong>Displayed Information</strong></h4><ul><li>Current analysis status</li><li>Relevant runtime information</li><li>Contextual data linked to the active measurement</li></ul><p>This table provides users with a concise overview of ongoing activities without needing to open additional dialogs.</p><h3><strong>Project, Batch Processing, and User Settings</strong></h3><p>In addition to direct analytical functions, the Instrument Window also provides access to broader data and workflow management tools.</p><h4><strong>Project Management</strong></h4><ul><li>Allows users to manage the <strong>current project</strong></li><li>Ensures all methods, analyses, and results are grouped consistently</li></ul><h4><strong>Batch Processing</strong></h4><ul><li>Opens the <strong>Batch dialog</strong></li><li>Enables processing of multiple chromatograms simultaneously</li><li>Useful for reprocessing data or applying consistent evaluation parameters</li></ul><h4><strong>Data Export Management</strong></h4><ul><li>Controls how data are exported from the software</li><li>Supports customization of export formats and workflows</li></ul><h4><strong>User Settings</strong></h4><ul><li>Allows modification of <strong>user-specific settings</strong></li><li>Settings are:<ul><li>Bound to the individual user</li><li>Stored within the user’s desktop file</li></ul></li></ul><p>This ensures a personalized working environment without affecting other users.</p><h3><strong>Practical Workflow Summary</strong></h3><p>In daily laboratory operation, the Instrument Window supports the following logical sequence:</p><ol><li>Define the method using <strong>Method Setup</strong></li><li>Configure samples via <strong>Single Analysis or Sequence</strong></li><li>Verify system readiness in <strong>Device Monitor</strong></li><li>Monitor signals in <strong>Data Acquisition</strong></li><li>Evaluate results in the <strong>Chromatogram Window</strong></li><li>Apply or refine <strong>Calibration</strong></li><li>Manage data through <strong>Batch Processing and Export</strong></li></ol><h3><strong>Conclusion</strong></h3><p>The Instrument Window in Clarity Chromatography Software serves as a centralized and highly structured interface that integrates method configuration, instrument control, real-time monitoring, data evaluation, and project management.</p><p>By organizing complex chromatographic tasks into clearly defined sections and workflow-driven icons, the software enables efficient and intuitive laboratory operation. Understanding the role of each component within the Instrument Window is essential for both routine analyses and advanced method development.</p>

Clarity Tutorial - Instrument window - Overview 

<h3><strong>Introduction</strong></h3><p><strong>This article provides a structured, technical explanation of the basic chromatogram integration workflow as demonstrated in a tutorial video for </strong><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/999"><span><strong>Clarity Chromatography Software</strong></span></a><strong>. The focus is on the Wave integration algorithm, although the general principles described apply equally to the Legacy algorithm available in Clarity.</strong></p><h3><strong>Overview of Integration in Clarity</strong></h3><p>In Clarity, chromatogram integration is performed from the <strong>Chromatogram window</strong>, using the <strong>Integration tab</strong>. Integration parameters are defined through a structured table, where each row represents one integration event or operation.</p><p>Clarity offers two integration algorithms:</p><ul><li><strong>Wave algorithm</strong> – modern, adaptive peak detection method (used in this guide)</li><li><strong>Legacy algorithm</strong> – traditional algorithm retained for compatibility</li></ul><p>Although parameter names and behavior may differ slightly, the overall integration workflow remains consistent.</p><h3><strong>Typical Integration Workflow</strong></h3><p>Chromatogram integration in Clarity follows a logical, multi-step process. In most cases, the first three steps are sufficient to obtain correct and reproducible peak integration.</p><h4><strong>Step 1: Define the Integration Interval</strong></h4><p>The integration interval specifies the <strong>time range of the chromatogram that will be evaluated</strong>. Any signal outside this interval is ignored during peak detection and quantification.</p><p><strong>Key points:</strong></p><ul><li>The interval is selected graphically in the chromatogram</li><li>After applying the integration function, Clarity automatically creates a new row in the integration table</li><li>Start and end times are taken from the graphical selection</li><li>All values in the integration table remain <strong>manually editable</strong>, allowing precise fine-tuning</li></ul><p>This step ensures that irrelevant regions (e.g. solvent front, column wash, late noise) do not influence peak detection.</p><h4><strong>Step 2: Enable Detection of Negative Peaks</strong></h4><p>If the chromatogram contains <strong>negative peaks</strong> (for example, due to detector behavior, background subtraction, or specific analytical techniques), the <i>Detect Negative Peaks</i> option must be enabled.</p><p>Failing to activate this function will cause negative peaks to be ignored during integration, potentially leading to incomplete or incorrect quantification.</p><h4><strong>Step 3: Adjust Global Integration Parameters</strong></h4><p>Global parameters define how peaks are detected across the <strong>entire integration interval</strong>. These settings establish the fundamental sensitivity and selectivity of peak detection.</p><h5><strong>Global Peak Width</strong></h5><ul><li>Represents the <strong>narrowest expected peak</strong></li><li>Used internally to determine peak bunching and separation</li><li>Critical for distinguishing closely eluting peaks</li></ul><h5><strong>Global Threshold</strong></h5><ul><li>Defines the <strong>noise level</strong></li><li>Signals below this threshold are considered noise and ignored</li><li>Proper adjustment prevents false peak detection</li></ul><h5><strong>Global Baseline Slope</strong></h5><ul><li>Controls how peak start and end points are determined</li><li>Helps adapt integration to sloping or drifting baselines</li></ul><p>In most routine applications, correct adjustment of these global parameters is sufficient for reliable peak integration.</p><h3><strong>Advanced Integration Adjustments</strong></h3><p>When global settings alone are not adequate, Clarity provides additional tools for localized and peak-specific refinement.</p><h4><strong>Step 4: Apply Local Integration Parameters</strong></h4><p>Local parameters apply <strong>only to a selected time range</strong> within the chromatogram. This approach is useful when:</p><ul><li>Peak shapes vary across the run</li><li>Specific regions require different sensitivity</li><li>Overlapping or poorly resolved peaks occur locally</li></ul><p>Clarity assists the user by <strong>suggesting suitable parameter values</strong>, which can then be accepted or further refined.</p><h4><strong>Step 5: Peak-Specific and Baseline Operations</strong></h4><p>For final fine-tuning, Clarity allows the use of:</p><ul><li><strong>Peak-specific parameters</strong></li><li><strong>Baseline operations</strong></li></ul><p>These operations target individual peaks or baselines and are typically applied to:</p><ul><li>Correct peak start/end points</li><li>Handle unusual peak shapes</li><li>Improve consistency for critical analytes</li></ul><p>This step is generally reserved for complex chromatograms or validated methods requiring strict control over integration behavior.</p><h3><strong>Integration Table Logic and Execution Order</strong></h3><p>Each row in the integration table represents <strong>one integration event</strong>. The order of rows is critical:</p><ul><li>Integration events are applied <strong>from top to bottom</strong></li><li>Later rows can modify or override results of earlier operations</li><li>Careful ordering ensures predictable and reproducible results</li></ul><h4><strong>Multi-Signal Chromatograms</strong></h4><p>In chromatograms containing multiple detector signals:</p><ul><li><strong>Each signal has its own integration table</strong></li><li>Integration parameters must be adjusted <strong>independently for each signal</strong></li></ul><p>This ensures correct peak detection and quantification across all recorded signals.</p><h3><strong>Transferring Integration to Methods and Other Data</strong></h3><p>Once the integration setup produces satisfactory results for a representative chromatogram, the completed integration table can be:</p><ul><li>Transferred into the <strong>analytical method</strong></li><li>Reused for <strong>other chromatograms</strong> measured under the same conditions</li></ul><p>This enables consistent processing, supports method validation, and improves long-term reproducibility.</p><h3><strong>Conclusion</strong></h3><p>Chromatogram integration in Clarity follows a structured and logical workflow, beginning with definition of the integration interval and global parameters, and progressing—only if necessary—to local and peak-specific adjustments.</p><p>In most routine applications:</p><ol><li>Integration interval</li><li>Negative peak detection</li><li>Global parameters</li></ol><p>are sufficient for reliable quantification. Advanced operations provide flexibility for complex or demanding chromatographic scenarios.</p><p>Understanding the hierarchy and execution order of integration events is essential for building robust, transferable methods and achieving consistent analytical results.</p>

Basics of Chromatogram Integration in Clarity Chromatography Software

<h3><strong>Introduction</strong></h3><p><strong>Modern analytical laboratories often operate multiple chromatographic instruments simultaneously, which places high demands on software usability and workspace navigation. </strong><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/products/999"><strong>Clarity Chromatography Software</strong></a><strong> developed by </strong><span><strong>DataApex</strong></span><strong> provides a structured, instrument-oriented user interface designed to simplify work even in complex multi-instrument environments. This article explains how to efficiently move between windows in Clarity.</strong></p><h3><strong>Concept of Instrument-Centric Workspace Organization</strong></h3><h4><strong>Instrument-Specific Color Schemes</strong></h4><p>Each instrument in Clarity is visually distinguished by its <strong>own color scheme</strong>. This design choice allows users to:</p><ul><li>Instantly recognize which windows belong to the same instrument</li><li>Avoid confusion when multiple instruments are open simultaneously</li><li>Maintain orientation within complex analytical workflows</li></ul><p>Color coding is consistent across all windows associated with a given instrument.</p><h3><strong>Types of Windows in Clarity</strong></h3><p>Within a single instrument context, Clarity typically provides access to several interconnected windows, including:</p><ul><li><strong>Instrument Window</strong> – the central control and overview window</li><li><strong>Chromatogram Window</strong> – displays acquired chromatographic data</li><li><strong>Sequence Window</strong> – manages sample sequences and runs</li></ul><p>Efficient navigation between these windows is essential for smooth operation.</p><h3><strong>Navigation Methods Between Windows</strong></h3><p>Clarity offers multiple complementary ways to switch between related windows. Users can choose the method that best fits their workflow preferences.</p><h4><strong>1. Instrument Window Tiles</strong></h4><p>Within the <strong>Instrument Window</strong>, large tiles represent related windows.</p><p><strong>Example workflow:</strong></p><ul><li>Select the <strong>large chromatogram tile</strong> to switch directly from the Instrument Window to the Chromatogram Window</li></ul><p>This tile-based approach is intuitive and visually guided.</p><h4><strong>2. Toolbar Icons</strong></h4><p>Each instrument window contains a <strong>toolbar with window icons</strong> that provide direct access to other related windows.</p><p><strong>Key characteristics:</strong></p><ul><li>The same set of window icons is available across all instrument-related windows</li><li>Enables quick transitions, for example:<ul><li>From Chromatogram Window → Sequence Window</li></ul></li><li>Ideal for experienced users who prefer icon-based navigation</li></ul><h4><strong>3. Window Menu</strong></h4><p>For users who prefer menu-driven control, Clarity includes a <strong>Window menu</strong>.</p><p><strong>Typical use case:</strong></p><ul><li>Select <strong>Main</strong> from the Window menu to return to the Clarity main window</li></ul><p>This method is particularly useful when:</p><ul><li>Navigating back to the global workspace</li><li>Managing multiple instruments at once</li></ul><h3><strong>Practical Navigation Workflow Example</strong></h3><p>A typical navigation sequence demonstrated in the video follows this logic:</p><ol><li>Start in the <strong>Instrument Window</strong></li><li>Click the <strong>Chromatogram tile</strong> to open chromatographic data</li><li>Use the <strong>toolbar icon</strong> to switch to the Sequence Window</li><li>Open the <strong>Window menu</strong> and select <i>Main</i> to return to the Clarity main interface</li></ol><p>This combination of tiles, icons, and menus ensures flexible and efficient workspace control.</p><h3><strong>Advantages of Clarity’s Navigation Design</strong></h3><p>The navigation system in Clarity provides several practical benefits:</p><ul><li><strong>Consistency</strong> – identical navigation tools across instrument windows</li><li><strong>Efficiency</strong> – rapid switching without losing context</li><li><strong>Scalability</strong> – effective even with many instruments open</li><li><strong>User preference flexibility</strong> – toolbar or menu-based workflows</li></ul><p>These features are especially valuable in high-throughput laboratories and 24/7 operational environments.</p><h3><strong>Conclusion</strong></h3><p>Clarity Chromatography Software uses a well-structured, instrument-oriented window system that simplifies navigation even in complex multi-instrument setups. By combining color-coded instruments, tile-based access, universal toolbar icons, and traditional menus, Clarity allows users to move quickly and confidently between windows.</p><p>Mastering these navigation techniques significantly improves workflow efficiency, reduces errors, and enhances overall user experience—making Clarity a robust platform for modern chromatographic laboratories.</p><p>For additional tutorials and practical demonstrations, users are encouraged to explore further educational resources provided by DataApex.</p>

How to switch between the Clarity Windows

<h3><strong>Introduction</strong></h3><p><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/999"><strong>Clarity Chromatography Software </strong></a><strong>from DataApex provides an extensive set of tools for zooming, navigation, and chromatogram orientation. The combination of mouse interactions, keyboard shortcuts, and the Preview Graph enables efficient and intuitive data inspection without loss of context, even at very high levels of magnification.</strong></p><h3><strong>Purpose of Zooming and Navigation in Chromatograms</strong></h3><p>Zoom and navigation tools in Clarity are designed to:</p><ul><li>Inspect fine peak structures and low-intensity signals</li><li>Compare closely eluting compounds</li><li>Adjust vertical scaling without losing horizontal context</li><li>Move efficiently between overview and detail views</li></ul><p>Together, these tools enable accurate qualitative inspection and reliable quantitative evaluation.</p><h3><strong>Zooming the Chromatogram</strong></h3><p>Clarity offers multiple complementary zoom methods, allowing users to work with either the mouse or keyboard.</p><h4><strong>Mouse-Based Zoom</strong></h4><ul><li><strong>Zoom to a specific region</strong><br>Click and drag with the mouse to select a rectangular area of the chromatogram.<br>The selected region becomes the new zoomed view.</li><li><strong>Zoom using the mouse wheel</strong><ul><li>Scroll the mouse wheel to zoom in or out.</li><li>Hold <strong>Ctrl</strong> and scroll to control zoom depth more precisely.</li></ul></li></ul><h4><strong>Keyboard Zoom Controls</strong></h4><ul><li><strong>Zoom in / out</strong><ul><li>Press <strong>+</strong> to zoom in</li><li>Press <strong>–</strong> to zoom out</li></ul></li><li><strong>Axis-specific zoom (Y-axis only)</strong><ul><li>Hold <strong>Ctrl + Shift</strong> while scrolling the mouse wheel<br>This adjusts signal intensity scaling without affecting retention time.</li></ul></li></ul><h3><strong>Resetting and Managing Zoom Levels</strong></h3><p>As work progresses, it is often necessary to reset or step through previous zoom states.</p><h4><strong>Unzoom (Reset View)</strong></h4><p>You can return to the full chromatogram using any of the following methods:</p><ul><li>Double-click anywhere in the graph</li><li>Press <strong>Ctrl + *</strong> (numeric keypad)</li><li>Select <strong>Unzoom</strong> from:<ul><li>The toolbar</li><li>The local (right-click) menu</li></ul></li></ul><h4><strong>Navigating Between Zoom Levels</strong></h4><p>Clarity stores zoom history, allowing you to move backward or forward between views:</p><ul><li>Use <strong>Previous Zoom</strong> and <strong>Next Zoom</strong> from:<ul><li>The toolbar</li><li>The local menu</li></ul></li><li>Or press <strong>Ctrl + +</strong> / <strong>Ctrl + –</strong> to step through zoom states</li></ul><p>This is particularly useful when comparing multiple regions of interest.</p><h3><strong>Moving Within a Zoomed Chromatogram</strong></h3><p>Once zoomed in, Clarity provides several intuitive ways to move around the visible area without changing zoom level.</p><h4><strong>Mouse Navigation</strong></h4><ul><li><strong>Vertical movement (Y-axis)</strong><br>Scroll the mouse wheel up or down.</li><li><strong>Horizontal movement (X-axis)</strong><br>Hold <strong>Shift</strong> and scroll the mouse wheel.</li><li><strong>Free panning</strong><br>Hold <strong>Ctrl</strong> and drag with the left mouse button to pan in any direction.</li></ul><h4><strong>Keyboard Navigation</strong></h4><ul><li>Use the <strong>arrow keys</strong> to shift the visible area:<ul><li>Left / Right arrows move along the time axis</li><li>Up / Down arrows move along the signal axis</li></ul></li></ul><p>This method is especially useful for fine, controlled adjustments.</p><h3><strong>Using the Preview Graph for Orientation</strong></h3><p>When working at high zoom levels, it can be difficult to maintain awareness of where you are within the full chromatogram. The Preview Graph solves this problem.</p><h4><strong>Activating the Preview Graph</strong></h4><ol><li>Right-click anywhere in the chromatogram area</li><li>Select <strong>Preview Graph</strong> from the local menu</li></ol><h4><strong>How the Preview Graph Works</strong></h4><ul><li>Displayed as a <strong>horizontal bar above the main chromatogram</strong></li><li>Shows the <strong>entire chromatogram</strong> in compressed form</li><li>Highlights the <strong>currently visible (zoomed) region</strong></li></ul><h4><strong>Navigating with the Preview Graph</strong></h4><ul><li><strong>Move the view</strong><br>Drag the highlighted region left or right to reposition the main view.</li><li><strong>Change zoom range</strong><br>Resize the highlighted area to adjust the displayed time window.</li></ul><p>The Preview Graph provides immediate visual context, reducing the risk of losing orientation during detailed inspections.</p><h3><strong>Integrated Workflow: Combining Tools Effectively</strong></h3><p>All navigation elements in Clarity—mouse gestures, keyboard shortcuts, menu commands, and the Preview Graph—are designed to work together. An efficient workflow typically involves:</p><ol><li>Zooming into a region of interest using mouse selection</li><li>Refining scale with keyboard or wheel-based zoom</li><li>Moving precisely using arrow keys or panning</li><li>Maintaining context and repositioning via the Preview Graph</li></ol><p>This integrated approach allows fast transitions between overview and detail without interrupting analytical focus.</p><h3><strong>Conclusion</strong></h3><p>Clarity provides a comprehensive and highly intuitive set of tools for chromatogram navigation. By mastering zoom functions, movement controls, and the Preview Graph, users gain full control over how chromatographic data is displayed and interpreted.</p><p>These features are essential for accurate peak inspection, method development, troubleshooting, and confident reporting—especially when working with complex or high-resolution chromatographic data.</p><blockquote><p>For additional tutorials and demonstrations, consult the official video resources from<a target="_blank" rel="noopener noreferrer" href="https://www.youtube.com/@DataapexPrague"><strong> DataApex</strong></a>.</p></blockquote>

Navigating and Zooming Chromatograms in Clarity Chromatography Software

<h3><strong>Introduction</strong></h3><p><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/999"><strong>Clarity Chromatography Software</strong></a><strong> from </strong><span><strong>DataApex</strong></span><strong> provides a comprehensive set of tools for working with multi-signal chromatograms and displaying multiple chromatograms simultaneously. The combination of intuitive mouse control, keyboard shortcuts, and flexible graph display options enables efficient signal management, clear identification of the active signal, and effective data comparison without loss of context, even when working with complex or densely overlaid chromatographic data.</strong></p><h3><strong>Overview of Multi-Signal Chromatograms</strong></h3><p>A <strong>multi-signal chromatogram</strong> contains more than one detector signal recorded simultaneously (e.g., UV at different wavelengths, multiple channels of an electrochemical detector, or combined detector outputs).<br>Clarity provides tools to selectively display, hide, and evaluate these signals without losing context or data integrity.</p><p>Key objectives when working with multi-signal data include:</p><ul><li>Maintaining a clear graphical view</li><li>Identifying the <strong>active signal</strong></li><li>Efficiently switching between signals</li><li>Comparing data across multiple chromatograms</li></ul><h3><strong>Opening Chromatograms and Selecting Signals</strong></h3><h4><strong>Signal Selection During File Opening</strong></h4><p>When opening a chromatogram file, Clarity allows users to <strong>pre-select which signals will be displayed</strong>:</p><ol><li>Open the <strong>Open Chromatogram</strong> dialog.</li><li>Locate the <strong>Signals</strong> section.</li><li>Check or uncheck individual signals before confirming the dialog.</li></ol><p>Unchecked signals are automatically hidden upon opening. This approach is especially useful when working with datasets containing many detector channels, as it reduces initial visual clutter.</p><h3><strong>Showing and Hiding Signals After Opening</strong></h3><h4><strong>Toolbar-Based Signal Control</strong></h4><p>Once the chromatogram is open, signals can be shown or hidden dynamically:</p><ul><li>Hold the <strong>Ctrl</strong> key and click on a <strong>signal icon</strong> in the toolbar.</li><li>The selected signal will toggle between visible and hidden states.</li></ul><p>In <strong>multi-signal chromatograms</strong>, signal icons are visually connected by a line, indicating their logical grouping.</p><blockquote><p><strong>Important rule:</strong><br>At least <strong>one signal must always remain visible</strong>. Clarity does not allow all signals to be hidden simultaneously.</p></blockquote><h3><strong>Understanding the Active Signal</strong></h3><h4><strong>Definition and Purpose</strong></h4><p>The <strong>active signal</strong> is the signal currently being edited or evaluated. It determines:</p><ul><li>Which peaks are integrated</li><li>Which results are displayed in tables</li><li>Which signal responds to user edits</li></ul><h4><strong>Visual Indicators of the Active Signal</strong></h4><p>Clarity highlights the active signal in several consistent ways:</p><ul><li><strong>Toolbar:</strong> The signal icon is highlighted.</li><li><strong>Legend:</strong> The active signal name appears in bold.</li><li><strong>Graph:</strong> The signal trace is visually emphasized.</li><li><strong>Results Table:</strong> Data corresponds exclusively to the active signal.</li></ul><p>This multi-layered highlighting ensures the user always knows which signal is currently in focus, reducing the risk of accidental edits to the wrong dataset.</p><h3><strong>Overlay Mode: Opening Multiple Chromatograms</strong></h3><h4><strong>Purpose of Overlay Mode</strong></h4><p><strong>Overlay mode</strong> allows multiple chromatograms to be displayed simultaneously in a single graph. This is essential for:</p><ul><li>Method development</li><li>Batch comparison</li><li>Stability and repeatability studies</li><li>Sample-to-sample comparison</li></ul><h4><strong>Opening Multiple Files</strong></h4><p>To activate overlay mode:</p><ol><li>Open the <strong>Open Chromatogram</strong> dialog.</li><li>Select multiple chromatogram files by:<ul><li>Holding <strong>Ctrl</strong> to select individual files, or</li><li>Holding <strong>Shift</strong> to select a continuous range.</li></ul></li><li>Confirm the selection to open all files together.</li></ol><p>All selected chromatograms are displayed in the same graphical window.</p><h3><strong>Managing Chromatograms in Overlay Mode</strong></h3><h4><strong>Showing and Hiding Individual Chromatograms</strong></h4><p>In overlay mode, each chromatogram behaves similarly to a signal:</p><ul><li>Hold <strong>Ctrl</strong> and click the chromatogram icon to hide or show it.</li><li>Hidden chromatograms appear only as an <strong>outline</strong> in the icon.</li><li>Alternatively, hold <strong>Ctrl</strong> and double-click the chromatogram name in the legend.</li></ul><p>This functionality enables rapid decluttering of the display while preserving access to all loaded data.</p><h3><strong>Graph Properties for Advanced Customization</strong></h3><h4><strong>Accessing Graph Properties</strong></h4><p>For more advanced display control:</p><ol><li>Open <strong>Graph Properties</strong>.</li><li>Navigate to the <strong>Signals</strong> tab.</li></ol><h4><strong>Available Customization Options</strong></h4><p><strong>Within this section, users can:</strong></p><ul><li>Adjust individual signal display settings</li><li>Assign specific <strong>colors</strong> to each signal</li><li>Enable <strong>graying out of inactive signals</strong></li><li>Improve contrast and readability in dense overlays</li><li>Maintain clarity even at high zoom levels</li></ul><p><strong>These options are particularly valuable when working with:</strong></p><ul><li>High-density overlays</li><li>Multiple signals with similar retention times</li><li>Detailed peak inspection</li></ul><h3><strong>Practical Benefits and Use Cases</strong></h3><p>By combining signal control, overlay mode, and graphical customization, Clarity enables:</p><ul><li>Faster data interpretation</li><li>Reduced risk of signal confusion</li><li>Efficient comparison of chromatographic runs</li><li>Cleaner visual presentation for reporting and review</li></ul><p>These features support both routine analytical workflows and advanced method development tasks.</p><h3><strong>Conclusion</strong></h3><p>Clarity provides a comprehensive set of tools for managing <strong>multi-signal chromatograms</strong> and <strong>multiple chromatograms</strong> within a single, coherent environment.<br>By selectively displaying signals, clearly identifying the active signal, leveraging overlay mode, and customizing graphical output, users can maintain full control over complex chromatographic datasets while keeping their workspace organized and interpretable.</p><p>This structured workflow enhances productivity, accuracy, and confidence during chromatographic data evaluation—making Clarity a powerful solution for modern analytical laboratories.</p>

How to manage multisignal chromatogram(s) in Clarity Chromatography Software

<h3><strong>Introduction</strong></h3><p><strong>Modern chromatographic laboratories often operate instruments with multiple detector configurations. Depending on the analytical task, an operator may need to run measurements using all available detectors or only a selected subset. Reconfiguring the system manually each time can be time-consuming and error-prone.</strong></p><p><strong>Launch Manager</strong> is a lightweight utility designed to address this challenge by enabling users to start <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/999"><strong>Clarity Chromatography Software</strong></a> with predefined configurations, known as <i>profiles</i>. Each profile launches Clarity with a specific instrument setup, streamlining daily workflows and reducing setup time.</p><p>This article provides a detailed explanation of how to use Launch Manager to create, duplicate, and manage multiple Clarity configurations, using a practical example with LED and PDA detectors.</p><h3><strong>Purpose of Launch Manager</strong></h3><p>Launch Manager allows users to:</p><ul><li>Define multiple startup profiles for Clarity</li><li>Associate each profile with a dedicated configuration file</li><li>Quickly switch between different detector setups</li><li>Automatically open selected instruments and projects</li><li>Create desktop shortcuts for direct access to specific configurations</li></ul><p>This approach is particularly useful in laboratories where instruments are frequently reconfigured or shared between different analytical tasks.</p><h3><strong>Example Scenario: LED and PDA Detector Configurations</strong></h3><p>In this example, two operational scenarios are required:</p><ol><li><strong>LED + PDA configuration</strong><br>Used when both detectors are needed simultaneously.</li><li><strong>LED-only configuration</strong><br>Used when measurements are performed using only the LED detector.</li></ol><p>Instead of manually enabling or disabling detectors each time, Launch Manager allows both scenarios to be prepared in advance as independent profiles.</p><h3><strong>Accessing Launch Manager</strong></h3><p>Launch Manager can be opened in two ways:</p><ul><li>From the <strong>Windows Start Menu</strong></li><li>Directly from the <strong>Clarity installation folder</strong></li></ul><p>Once launched, the main window displays all existing profiles available on the system.</p><h3><strong>Understanding the Launch Manager Main Window</strong></h3><p>The main interface provides:</p><ul><li>A list of all defined profiles</li><li>Options to launch a selected profile</li><li>Access to profile management via <strong>Edit Profiles</strong></li></ul><p>From this window, users can either start Clarity using an existing profile or create and modify profiles as needed.</p><h3><strong>Creating a New Profile</strong></h3><h4><strong>Step 1: Open Profile Editor</strong></h4><ul><li>Click <strong>Edit Profiles</strong></li><li>Select <strong>Add</strong> to create a new profile</li></ul><h4><strong>Step 2: Define Profile Information</strong></h4><p>For each profile:</p><ul><li>Enter a <strong>profile name</strong> (e.g., <i>LED + PDA</i>)</li><li>Optionally add a <strong>short description</strong> to clearly identify the setup</li></ul><p>Clear naming is recommended, especially when multiple configurations are used regularly.</p><h3><strong>Assigning a Configuration File</strong></h3><p>Each Launch Manager profile is linked to a <strong>Clarity configuration file</strong>, which defines:</p><ul><li>Which devices are assigned to each instrument</li><li>How many instruments are available</li><li>Which detectors are enabled</li></ul><p>For the LED + PDA profile:</p><ul><li>Select an existing configuration that already includes both detectors</li><li>Duplicate the configuration and save it under a new name</li></ul><p>This ensures that each profile has its own independent configuration file.</p><h3><strong>Automatic Instrument and Project Loading</strong></h3><p>Launch Manager allows additional startup behavior to be defined:</p><ul><li>Automatically open <strong>Instrument 1</strong> after Clarity starts</li><li>Automatically load a selected <strong>Work Project</strong></li></ul><p>This further reduces manual steps after launching the software.</p><h3><strong>Creating Desktop Shortcuts</strong></h3><p>For faster access, Launch Manager can generate:</p><ul><li>A <strong>dedicated desktop shortcut</strong> for each profile</li></ul><p>Using shortcuts, Clarity can be started directly with the required configuration, without opening Launch Manager first.</p><h3><strong>Duplicating an Existing Profile</strong></h3><p>To create the <strong>LED-only</strong> setup:</p><ol><li>Duplicate the existing <strong>LED + PDA</strong> profile</li><li>Duplicate the associated configuration file again</li><li>Save the new configuration under a different name</li></ol><p>Duplicating profiles ensures consistency while minimizing setup effort.</p><h3><strong>Modifying the Configuration (Removing the PDA Detector)</strong></h3><h4><strong>Step 1: Launch the Profile</strong></h4><ul><li>Close the profile editor</li><li>Start Clarity by double-clicking the new profile or clicking <strong>Launch</strong></li></ul><h4><strong>Step 2: Edit Configuration in Clarity</strong></h4><ul><li>Open the configuration editor using the standard Clarity workflow</li><li>Remove the <strong>PDA detector</strong> from the device configuration</li><li>Confirm changes by clicking <strong>OK</strong></li></ul><p>The modifications are saved directly into the configuration associated with the active Launch Manager profile.</p><h3><strong>Finalizing and Using Profiles</strong></h3><p>After completing the configuration adjustments:</p><ul><li>Both profiles are fully prepared:<ul><li><strong>LED + PDA</strong></li><li><strong>LED only</strong></li></ul></li><li>Users can switch between setups simply by selecting the appropriate profile</li></ul><p>No further configuration changes are required when switching between measurement modes.</p><h3><strong>Verifying the Active Configuration</strong></h3><p>When opening the <strong>LED + PDA</strong> profile:</p><ul><li>The <strong>Device Monitor</strong> confirms that both detectors are connected</li><li>Both detectors are ready for simultaneous operation</li></ul><p>This visual verification ensures that the correct configuration is active before measurements begin.</p><h3><strong>Benefits of Using Launch Manager</strong></h3><p>Implementing Launch Manager provides several practical advantages:</p><ul><li>Faster startup with predefined setups</li><li>Reduced risk of configuration errors</li><li>Easy management of multiple detector combinations</li><li>Improved daily efficiency in multi-instrument environments</li></ul><p>By separating configurations into clearly defined profiles, laboratories can maintain flexibility without sacrificing reliability.</p><h4><strong>Conclusion</strong></h4><p>Launch Manager is a simple yet powerful tool for organizing and managing multiple Clarity configurations. By creating dedicated profiles for different detector combinations, users can switch between analytical setups quickly and consistently.</p><p>This approach is especially valuable in laboratories with shared instruments, variable detector usage, or frequent method changes. Proper use of Launch Manager can save time every day while ensuring correct and reproducible instrument operation.</p>

Clarity Launch Manager - Overview 

<h3><strong>We're excited to announce that </strong><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/999"><strong>Clarity Chromatography Software</strong></a><strong> version 10.1.2 is now available!</strong></h3><p><strong>This minor update expands Clarity’s portfolio with new control modules.</strong></p><h4><strong>Newly added Instrument control modules</strong></h4><ul><li>Ecom auxiliary modules</li><li>HTA ICF control modules</li><li>Spark pump</li></ul><h4><strong>Updated Instrument control modules</strong></h4><ul><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/companies/168"><strong>Ecom</strong></a> HPLC</li><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/companies/328"><strong>Knauer</strong></a> HPLC</li><li>Spark ICF control modules</li><li>YoungIn Chromass HPLC</li></ul><blockquote><p>For a complete list of module changes, see the <a target="_blank" rel="noopener noreferrer" href="https://www.dataapex.com/version_history?product=1"><strong>Changelog</strong></a>. For more info about exciting new features directly in Clarity, explore what was introduced in the <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/article/5622"><strong>Clarity 10.1 release highlights</strong></a>.</p><p>Clarity can control <strong>1000+ instruments</strong>; the <a target="_blank" rel="noopener noreferrer" href="https://www.dataapex.com/controls"><strong>list can be previewed here</strong></a>.</p></blockquote><h4><strong>Supported Instruments in Clarity (DataApex) — Quick Guide</strong></h4><p>Clarity Chromatography Software supports a wide range of chromatographs and peripherals via <strong>digital control (DD)</strong> and <strong>analog acquisition (A/D)</strong> using the <strong>Colibrick</strong> module.</p><h5><strong>Gas Chromatographs (GC)</strong></h5><p>Digital integration over LAN/RS232 (many via ICF):</p><ul><li><strong>Agilent</strong>: 5890, 6890, 7890, 8860, 8890, <strong>Intuvo 9000</strong></li><li><strong>Shimadzu</strong>: GC-2010/2014, <strong>Nexis GC-2030</strong></li><li><strong>Thermo Fisher</strong>: TRACE 1300/1310</li><li><strong>PerkinElmer</strong>: Clarus 400–690</li><li>Also supported: <strong>Dani</strong>, <strong>Ellutia</strong>, <strong>Young In Chromass</strong>, <strong>Apix</strong>, <strong>Fuli</strong>, <strong>GOW-MAC</strong> (selected models)</li></ul><blockquote><p>Note: Most Agilent 6890–8890 and Intuvo use <strong>LAN – ICF</strong>.</p></blockquote><h5><strong>HPLC Systems</strong></h5><p>Full system/module control:</p><ul><li><strong>Agilent</strong> 1100–<strong>1290 Infinity II</strong> (ICF)</li><li><strong>Shimadzu</strong> LC-10/20 and <strong>Nexera LC-40</strong></li><li><strong>PerkinElmer</strong> Flexar / NexSAR</li><li><strong>Knauer</strong> Azura / BlueShadow / Smartline</li><li><strong>Hitachi</strong> Chromaster / Primaide</li><li><strong>Young In Chromass</strong> ChroZen series</li><li><strong>Sykam</strong> S500–S600, <strong>Watrex</strong> Streamline, <strong>Hanon</strong> LC7000–7300</li></ul><h5><strong>HPLC Modules (Pumps, Detectors, Ovens, Fraction Collectors)</strong></h5><ul><li><strong>Pumps</strong>: Agilent 1100–1290 families, Knauer, Shimadzu, PerkinElmer, Sykam, SSI, Ecom</li><li><strong>Detectors</strong>: VWD/DAD(PDA)/RID/FLD/ELSD across Agilent, Shimadzu, Knauer, PerkinElmer, Young In Chromass, Ecom, etc.</li><li><strong>Column Ovens</strong>: Agilent G1316x / G7116x, Shimadzu CTO-20/30/40, Knauer CT2.1, PerkinElmer Flexar</li><li><strong>Fraction Collectors</strong>: Knauer FC 6.1, Teledyne FOXY series, Ecom ECF 2096, Waters Fraction Collector II</li></ul><h5><strong>Autosamplers</strong></h5><ul><li><strong>Agilent</strong> GC ALS (7673/7683/7693/8697), HPLC ALS modules (G1313A–G7167C)</li><li><strong>Shimadzu</strong> AOC-20 / AOC-5000+, SIL-10 / SIL-20 / <strong>SIL-40</strong> series</li><li><strong>CTC Analytics PAL</strong>, <strong>HTA</strong> autosamplers, <strong>Spark</strong> Alias/UHPLC, <strong>Knauer</strong> AS 6.1L</li><li><strong>PerkinElmer</strong> Flexar / NexSAR AS</li></ul><h5><strong>Other Devices</strong></h5><ul><li><strong>GC×GC modulators</strong> (e.g., Charles University GC×GC Modulator)</li><li><strong>Valves &amp; switch modules</strong> (Agilent, Knauer, Shimadzu, VICI-Valco)</li><li><strong>Degassers, flow monitors, managers, interfaces</strong></li><li><strong>LC-MS / GC-MS</strong>: Advion Expression CMS, Microsaic 4500 MiD, Markes BenchTOF (and others)</li><li><strong>Balances (EA extension)</strong>: Mettler Toledo, Sartorius</li></ul><h5><strong>Analog Acquisition (Colibrick)</strong></h5><p>A/D support for legacy or analog-output devices:</p><ul><li><strong>GC</strong>: Agilent 5880/4890A, Varian 3xxx/3800/3900, PerkinElmer Clarus series, Thermo TRACE, Shimadzu GC-14/9A, Scion 43x/45x/83xx/85xx, etc.</li><li><strong>HPLC Detectors</strong>: Waters 2487/2489, ESA Corona, Hitachi L-series, JASCO FP/UV, Ecom LCD series, many others</li><li><strong>Elemental &amp; Amino Acid Analyzers</strong>: Carlo Erba/Costech ECS, Biochrom 20/30+</li></ul><p>If you are interested in a <strong>DEMO VERSION</strong>, contact us!</p>

DataApex Clarity Chromatography software 10.1.2 just released!

<p><strong>Clarity 10.2 expands instrument control capabilities with new control modules and updates the MS extension to help you work more efficiently.</strong></p><h4><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/999"><strong>Clarity</strong></a><strong> 10.2 highlights</strong></h4><ul><li>New and updated control modules</li><li>Improved MS data import and export</li><li>Obsolete hardware support ended</li></ul><h4><strong>Instrument control modules</strong></h4><p>Clarity 10.2 introduces new instrument control modules from Annuo (AS-3117, FAS-3823) and updated instrument controls form Sykam and Ecom.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Data_Apex_Instrument_control_modules_5de26782b0.jpg" alt="DataApex: Instrument control modules" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Data_Apex_Instrument_control_modules_5de26782b0.jpg 228w," sizes="100vw" width="380" height="260"></p><h4><strong>MS data import/export improvements</strong></h4><p>Clarity improves MS data exchange, especially for *.cdf files. MS instruments now support export and import of multiple spectral data and non-spectral signal data in the same CDF file. Import also better handles uniform sampling information, m/z Step values, scale factors, and file names with non-ASCII characters. Exporting individual chromatogram signals from MS instruments is now available through a separate Export Chromatogram dialog.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Data_Apex_MS_data_import_export_improvements_a7967a4020.jpg" alt="DataApex: MS data import-export improvements" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Data_Apex_MS_data_import_export_improvements_a7967a4020.jpg 228w," sizes="100vw" width="378" height="259"></p><h4><strong>Obsolete hardware support terminated</strong></h4><p>Due to changes in Windows driver security requirements, this update discontinues support for obsolete hardware, including INT7, INT9, U-PAD, U-PAD2, and CB20.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Data_Apex_Obsolete_hardware_support_terminated_24d9329419.jpg" alt="DataApex: Obsolete hardware support terminated" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Data_Apex_Obsolete_hardware_support_terminated_24d9329419.jpg 228w," sizes="100vw" width="378" height="259"></p><blockquote><p><strong>Explore the complete list of all changes, fixes, and additions in version 10.2.</strong></p><p><strong>👉</strong><a target="_blank" rel="noopener noreferrer" href="https://www.dataapex.com/version_history?product=1"><strong>See the complete changelog&nbsp;</strong></a></p></blockquote>

Clarity Chromatography Software 10.2 released!

<p><strong>Is your lab ready for the new academic year? As students and teachers return to the laboratory, now is a great time to prepare your chromatography systems for the semester ahead.</strong></p><p>Now with <strong>20% total discount</strong> on a <strong>new </strong><a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/all/products/999"><strong>Clarity Chromatography Software</strong></a> for customers from educational institutions. In addition, customers purchasing a new license for Clarity Chromatography Software will receive a <strong>free copy of </strong><a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/all/products/1000"><strong>Clarity Offline Chromatography Software</strong></a>.</p><blockquote><p class="cke-user_style-important"><strong>👉Promotion code: MKT2114</strong></p><p>The offer is valid through the <strong>end of October 2026.</strong></p></blockquote><p><strong>The latest version of Clarity Chromatography Software - 10.2 was released in June 2026! </strong><a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/all/article/7512"><strong>Read the article HERE.</strong></a></p>

Back to School: 20% Off Clarity Chromatography Software

Software

Article

Product

Events

Webinars

Application

Academy

Video

Poster

Scientists

Plastics

Environment

Food

Water

Health

Presentation

Scientific article

Interview

Toxicology

Popularization

Science and research

Covid-19

Career

Laboratories

Various

Zaměření

Type of News

Focus

Since 1991 DataApex develops and manufactures chromatography data stations. DataApex is constantly striving to provide users with efficient and up-to-date tools for chromatography data processing.

Back to School: 20% Off Clarity Chromatography Software

Clarity Chromatography Software 10.2 released!

DataApex Clarity Chromatography software 10.1.2 just released!

Clarity Launch Manager - Overview

How to manage multisignal chromatogram(s) in Clarity Chromatography Software

Navigating and Zooming Chromatograms in Clarity Chromatography Software

How to switch between the Clarity Windows

Basics of Chromatogram Integration in Clarity Chromatography Software

Clarity Tutorial - Instrument window - Overview

Season’s Greetings from DataApex

Upcoming events

Thermo Fisher Scientific Omics User Meeting 2026

Thermo Fisher Scientific Mass Spectrometry Users’ Meetings 2026

The International School on Mass Spectrometry (IntSMS) 2026

Webinars

TechTalk: Benefits of high-resolution ICP-OES for challenging applications

LC-MS/MS Analysis of Nitrosamines using novus V55

GLP-1 & GIP under the lens: HRMS strategies for synthetic peptide profiling