Remote Deep-Ultraviolet Laser Ablation in Connection with Electrospray Ionization–Atmospheric Pressure Chemical Ionization (rDUVLAESCI): A Novel Dual Ionization Source for Molecular Mass Spectrometry
LCMSScientific article | Science and research

Remote Deep-Ultraviolet Laser Ablation in Connection with Electrospray Ionization–Atmospheric Pressure Chemical Ionization (rDUVLAESCI): A Novel Dual Ionization Source for Molecular Mass Spectrometry

This study introduces a novel remote deep-UV laser ablation dual-ionization source for molecular mass spectrometry and imaging with enhanced spatial resolution.
Remote Deep-Ultraviolet Laser Ablation in Connection with Electrospray Ionization–Atmospheric Pressure Chemical Ionization (rDUVLAESCI): A Novel Dual Ionization Source for Molecular Mass Spectrometry
Evaluation of ion pairing reversed-phase liquid chromatography for the separation of large RNA molecules
LCMSScientific article | Various

Evaluation of ion pairing reversed-phase liquid chromatography for the separation of large RNA molecules

The goal of this study is to optimize IP-RPLC for separating and characterizing large RNA molecules, enhancing RNA quality attribute analysis for therapeutic development.
Evaluation of ion pairing reversed-phase liquid chromatography for the separation of large RNA molecules
Understanding the fundamentals of the on-off retention mechanism of oligonucleotides and their application to high throughput analysis
LCMSScientific article | Various

Understanding the fundamentals of the on-off retention mechanism of oligonucleotides and their application to high throughput analysis

The goal of this study is to investigate oligonucleotide elution behavior in IP-RPLC under various mobile phase conditions and develop ultra-fast separation methods for therapeutic oligonucleotides.
Understanding the fundamentals of the on-off retention mechanism of oligonucleotides and their application to high throughput analysis
News from LabRulezLCMS Library - Week 2, 2025
LCMSArticle | Application

News from LabRulezLCMS Library - Week 2, 2025

This week we bring you documents by ALS Europe, Thermo Fisher Scientific, Agilent Technologies, Shimadzu, Metrohm, and Waters Corporation.
News from LabRulezLCMS Library - Week 2, 2025
News from LabRulezLCMS Library - Week 50, 2024
LCMSArticle | Application

News from LabRulezLCMS Library - Week 50, 2024

This week we bring you applications by Shimadzu, Metrohm, and Waters Corporation, a presentation by Agilent Technologies, and a poster from MSACL by Thermo Fisher Scientific!
News from LabRulezLCMS Library - Week 50, 2024
News from LabRulezLCMS Library - Week 49, 2024
LCMSArticle | Application

News from LabRulezLCMS Library - Week 49, 2024

This week we bring you applications by Thermo Fisher Scientific, Shimadzu, Waters Corporation, Agilent Technologies, and Metrohm!
News from LabRulezLCMS Library - Week 49, 2024
News from LabRulezLCMS Library - Week 48, 2024
LCMSArticle | Application

News from LabRulezLCMS Library - Week 48, 2024

This week we bring you applications by Thermo Fisher Scientific, Shimadzu, Waters Corporation, and Agilent Technologies!
News from LabRulezLCMS Library - Week 48, 2024
News from LabRulezGCMS Library - Week 47, 2024
GCMSArticle | Application

News from LabRulezGCMS Library - Week 47, 2024

This week we bring you applications and posters by Agilent Technologies, Thermo Fisher Scientific, Metrohm, and Shimadzu!
News from LabRulezGCMS Library - Week 47, 2024
News from LabRulezLCMS Library - Week 47, 2024
LCMSArticle | Application

News from LabRulezLCMS Library - Week 47, 2024

This week we bring you applications, presentations, and posters by Metrohm, Thermo Fisher Scientific, Shimadzu, Waters Corporation, and Agilent Technologies!
News from LabRulezLCMS Library - Week 47, 2024
Improving the Accuracy of Predictive 2D-LC Optimization Strategies: Incorporation of Simulated Elution Profiles to Account for Injection Band Broadening in Online Comprehensive Two-Dimensional Liquid Chromatography
LCMSArticle | Scientific article

Improving the Accuracy of Predictive 2D-LC Optimization Strategies: Incorporation of Simulated Elution Profiles to Account for Injection Band Broadening in Online Comprehensive Two-Dimensional Liquid Chromatography

A novel approach for optimizing online comprehensive LC × LC methods, addressing the challenges posed by second-dimension injection band broadening under sample solvent mismatch or volume overload.
Improving the Accuracy of Predictive 2D-LC Optimization Strategies: Incorporation of Simulated Elution Profiles to Account for Injection Band Broadening in Online Comprehensive Two-Dimensional Liquid Chromatography