Remote Deep-Ultraviolet Laser Ablation in Connection with Electrospray Ionization–Atmospheric Pressure Chemical Ionization (rDUVLAESCI): A Novel Dual Ionization Source for Molecular Mass Spectrometry
This study introduces a novel remote deep-UV laser ablation dual-ionization source for molecular mass spectrometry and imaging with enhanced spatial resolution.
Evaluation of ion pairing reversed-phase liquid chromatography for the separation of large RNA molecules
The goal of this study is to optimize IP-RPLC for separating and characterizing large RNA molecules, enhancing RNA quality attribute analysis for therapeutic development.
Understanding the fundamentals of the on-off retention mechanism of oligonucleotides and their application to high throughput analysis
The goal of this study is to investigate oligonucleotide elution behavior in IP-RPLC under various mobile phase conditions and develop ultra-fast separation methods for therapeutic oligonucleotides.
This week we bring you applications by Shimadzu, Metrohm, and Waters Corporation, a presentation by Agilent Technologies, and a poster from MSACL by Thermo Fisher Scientific!
This week we bring you applications, presentations, and posters by Metrohm, Thermo Fisher Scientific, Shimadzu, Waters Corporation, and Agilent Technologies!
Improving the Accuracy of Predictive 2D-LC Optimization Strategies: Incorporation of Simulated Elution Profiles to Account for Injection Band Broadening in Online Comprehensive Two-Dimensional Liquid Chromatography
A novel approach for optimizing online comprehensive LC × LC methods, addressing the challenges posed by second-dimension injection band broadening under sample solvent mismatch or volume overload.