The 13th Conference of Czech Society for Mass Spectrometry & 11th Informal proteomic meeting - Day 1
Day 1 in České Budějovice featured an Orbitrap plenary by Alexander Makarov, sessions on exposome, proteomics and structural MS, sponsor talks, flash talks and an evening networking reception.
The Plant of Many Scents: Unraveling the Odorant Composition of Selected CBD Hemp Cultivars
Aroma analysis of six CBD hemp cultivars revealed 52 odor-active compounds, many new to hemp. Key terpenes and potent sulfur odorants drive distinct scent profiles across varieties.
Regenerating liver uses ammonia to support de novo pyrimidine synthesis and cell proliferation
Regenerating liver redirects ammonia metabolism to fuel de novo pyrimidine synthesis, enabling cell proliferation and tissue repair after hepatectomy through metabolic reprogramming.
Molecular Sensory Analysis Confirms Wood Smoke Exposure as a Source of Smoky Off-Flavors in Fermented Cocoa
Molecular sensory analysis confirmed that wood smoke during cocoa drying causes smoky off-flavors. Major odorants were found in both nibs and husks, showing limited removal during processing.
Synthesis and Evaluation of Pyridine-Based Antibacterial Agents that Inhibit ATP Synthase in Acinetobacter baumannii
A new class of trisubstituted pyridines targets ATP synthase in Acinetobacter baumannii. Four lead compounds showed potent antibacterial effects and synergized with colistin against multidrug-resistant strains.
Determination of Chemical Mixtures in Environmental, Food, and Human Samples Using High-Resolution Mass Spectrometry-Based Suspect Screening Approaches
Suspect screening using LC- and GC-HRMS identified 547 chemicals across environmental, food, and human samples. Pharmaceuticals, pesticides, and personal care products were the most frequent contaminants.
The Chemical and Enantioselective Analysis of a New Essential Oil Produced by the Native Andean Species Aiouea dubia (Kunth) Mez from Ecuador
Essential oil from Aiouea dubia leaves was analyzed by GC–MS/FID and enantioselective GC. Major terpenes and chiral profiles suggest antibacterial and anti-inflammatory potential for cosmeceutical use.
Microwave-Assisted Digestion Method and Dispersive Magnetic Solid-Phase Microextraction for the Determination of Major and Trace Elements in Lignocellulosic Biomass by ICP-OES
This study introduces microwave-assisted digestion and dispersive magnetic SPE with ICP-OES to measure major and trace elements in lignocellulosic biomass with high accuracy and sensitivity.
Hydrophilic Interaction Chromatography HRMS with Acrylamide Monolithic Columns: A Novel Approach for Intact Antibody Glycoform Characterization
This study introduces acrylamide monolith HILIC-MS for intact mAb glycoprofiling, offering high selectivity, baseline separation, and detection of low-abundance glycoforms missed by RPLC-MS.
Ion-Pairing Hydrophilic Interaction Chromatography for Impurity Profiling of Therapeutic Phosphorothioated Oligonucleotides
Ion-pairing HILIC improves impurity profiling of therapeutic oligonucleotides. It resolves deaminated impurities from full-length products, beyond current LC-MS limits.
