<p><strong>Our Library never stops expanding. What are the most recent contributions to LabRulezGCMS Library in the week of 28th July 2025? Check out new documents from the field of the gas phase, especially GC and GC/MS techniques!</strong></p><blockquote><p><span style="font-size:20px;">👉 </span><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library"><span style="font-size:20px;"><strong>SEARCH THE LARGEST REPOSITORY OF DOCUMENTS ABOUT GCMS AND RELATED TECHNIQUES</strong></span></a></p></blockquote><blockquote><p><strong>👉 Need info about different analytical techniques?</strong> Peek into <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/library"><strong>LabRulezLCMS</strong></a> or <a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/library"><strong>LabRulezICPMS</strong></a> libraries.</p></blockquote><p>This week we bring you posters by <strong>Agilent Technologies / ASMS, Shimadzu / ASMS, </strong>presentation by<strong> UCT / MDCW </strong>and other document by<strong> ALS Czech Republic!</strong></p><h3><strong>1. Agilent Technologies / ASMS: Detection of VOCs by Agilent 8697 Headspace with 7010D GC/MS/MS Using Hydrogen Carrier Gas</strong></h3><ul><li>Poster</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/ps_7010d_hydrogen_carrier_volatiles_asms_2025_tp_274_en_agilent_1d1f7b5b0a.pdf"><strong>Full PDF for download</strong></a></li></ul><p>Volatile organic compounds (VOCs) are present in the environment and can alter the chemistry of the atmosphere. Current methods for analyzing these compounds use gas chromatography with a single quadrupole detector and the sample is introduced using a purge and trap1 . With a triple quadrupole mass spectrometer (GC/TQ) as a detector, we can acquire in dynamic MRM (dMRM) mode which enables lower detection levels by minimizing interference from coeluting compounds. Along with this TQ detector, we employed headspace as our sample introduction method and hydrogen carrier gas.</p><h4><strong>Experimental</strong></h4><p>Agilent <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library?mainauthorItems=10&amp;search=8890+GC"><strong>8890 GC </strong></a>with <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library?mainauthorItems=10&amp;search=8697+headspace"><strong>8697 headspace</strong></a> and <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library?mainauthorItems=10&amp;search=7010D+TQ"><strong>7010D TQ</strong></a> was used for this analysis.A 20 m x 180 µm x 1 µm <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library?instrumentationItems=19&amp;mainauthorItems=10&amp;search=DB-624"><strong>DB-624 column</strong></a> was used with a constant flow rate of 0.6 mL/min of hydrogen.&nbsp;</p><h4><strong>Conclusions</strong></h4><p><strong>All 72 compounds successfully calibrated over multiple orders of magnitude using a combination of new techniques for VOC analysis.&nbsp;</strong></p><ul><li>Hydrogen carrier gas does not drastically diminish sensitivity.&nbsp;</li><li>The 7010D TQ in dMRM mode enables sensitivity to detect low ppb levels.&nbsp;</li><li>Static headspace is a reproducible sample introduction technique for VOCs.&nbsp;</li><li>Further method development may be necessary to improve peak shape of the gases.</li></ul><h3><strong>2. ALS Czech Republic: Determination of Polychlorinated Naphthalenes in Solid and Aqueous Matrices</strong></h3><ul><li>Other document</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/enviromail_27_europe_determination_of_polychlorinated_naphthalenes_in_solid_and_aqueous_matrices_1983a3deb8.pdf"><strong>Full PDF for download</strong></a></li></ul><p>PCNs are a class of compounds in which hydrogen atoms are replaced by chlorine atoms in the naphthalene ring. In total, 75 congeners have been identified according to the number and position of the chlorine atoms (positions 1 to 8), their general formula is C10H8-nCln. Individual congeners differ in their degree of chlorination and physicochemical properties. Due to their persistence and toxicity, PCNs are considered to be significant environmental contaminants.</p><p>Due to their high thermal stability, hydrophobicity, and inertness, PCNs served as dielectric fluids in capacitors, insulating materials for wires and cables, wood preservatives, retardants, engine oil additives, and as raw materials for dye production. Estimated production of technical PCNs was 150,000–400,000 tons. Historical manufacturing and improper disposal represent significant sources of environmental contamination. Additionally, PCNs are formed as unintentional byproducts in various industrial processes, such as municipal solid waste incineration, iron ore sintering, secondary copper smelting, and other metallurgical operations. Even though the production and use of PCNs are now strictly regulated or banned, the legacy of early production and current unintentional releases has resulted in their detection across various environmental media and in food.</p><h4><strong>Human Health Risks Associated with PCNs</strong></h4><p>Exposure to PCNs has been linked to various adverse health effects, such as neurotoxicity, hepatotoxicity, immune suppression, and endocrine disruption, which can cause reproductive and developmental problems. Higher chlorinated PCNs, particularly hexachloronaphthalene, are especially toxic and may act similarly to dioxins. Due to their persistence, toxicity, and bioaccumulation, PCNs were added to the Stockholm Convention in 2015. Accurate quantification of PCNs emissions is essential for effective policy and risk management. Although global inventories are limited, recent studies identify key sources, including iron and steel production, waste incineration, and non-ferrous metal industries. New global emission inventories, using modeling methods and atmospheric transport analysis, are crucial for understanding PCNs distribution and guiding targeted reduction strategies to minimize environmental and health risks.</p><h4><strong>Determination of PCNs in ALS Laboratories</strong></h4><p>At ALS we use the most modern analytical method for the determination of PCNs that covers determination of chlorinated groups from monochloronaphthalenes to octachlorophthalenes and, if necessary, selected congeners (Table 1) in waste, aqueous and solid matrices.</p><p>For these purposes, we use gas chromatography coupled with high-resolution mass spectrometry (<a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library?instrumentationItems=5"><strong>GCHRMS</strong></a>) or <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library?instrumentationItems=15-3-4"><strong>gas chromatography coupled with tandem mass spectrometry with a triple quadrupole</strong></a> (GC-MS/ MS). Both techniques use electron ionization and are based on the isotope dilution method using isotopelabeled standards, ensuring high accuracy and reliability of results. The developed method achieves limits of quantification defined by EU Regulation 2019/1021 on persistent organic pollutants, making it suitable for comparison of results with legislatively established limits.</p><h3><strong>3. UCT Prague / MDCW: Analysis of the human scent on the cartridge cases using GC×GC-MS/TOF</strong></h3><ul><li>Presentation</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/FL_04_urban_lutychf_d2083b6570.pdf"><strong>Full PDF for download</strong></a></li></ul><p>This presentation explores an innovative forensic approach—identifying human scent signatures on spent cartridge cases using advanced analytical instrumentation. The study investigates whether scent could serve as a reliable alternative to traditional dactyloscopic (fingerprint) methods, especially when fingerprints are smudged or missing.</p><h4><strong>Analytical Technique</strong></h4><p>The scent analysis was carried out using <strong>comprehensive two-dimensional gas chromatography coupled with time-of-flight mass spectrometry (</strong><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library?instrumentationItems=13-3-2"><strong>GC×GC-TOF-MS</strong></a><strong>)</strong>, a powerful tool capable of detecting and resolving complex scent profiles.</p><h4><strong>Key Motivations</strong></h4><ul><li><strong>Thermal Stability of Human Scent:</strong> Certain scent components, specifically ethyl esters of higher fatty acids, remain intact even after exposure to 500 °C for one minute—surviving firearm discharge.</li><li><strong>Complexity of Human Scent:</strong> Human scent consists of fractions of various volatility; less volatile compounds play a critical role in canine-based olfactory identification.</li></ul><h4><strong>Pilot Study: Simulated Crime Scene</strong></h4><ul><li>4 volunteers + 1 shooter</li><li>12 scent samples collected on <strong>glass beads</strong> and 4 <strong>unknown scent samples</strong> collected from <strong>cartridge cases</strong></li><li>Various surfaces: plastic, wood, concrete</li></ul><h4><strong>Data Processing &amp; Comparison</strong></h4><ul><li>Peak alignment using <strong>Kováts retention indices</strong></li><li>Selection of robust markers: present in ≥75% of volunteer samples and found on at least one cartridge</li><li>Comparison based on <strong>area ratios</strong> of 150 lowest-variance substances</li><li><strong>Cluster analysis</strong> confirmed clear scent differentiation</li></ul><h4><strong>Results &amp; Conclusions</strong></h4><ul><li>Distinct scent profiles were successfully differentiated among individuals.</li><li>Trained police dogs validated these findings by accurately matching samples.</li><li>The <strong>type of surface</strong> (plastic, wood, concrete) on which the cartridge was found <strong>did not significantly affect</strong> scent retention or identification.</li></ul><h4><strong>Future Directions</strong></h4><ul><li>Aligning analytical sensitivity between glass beads and cartridge cases.</li><li>Reducing scent adsorption time on cartridges.</li><li>Combining scent and fingerprint analysis from the same trace.</li><li>Expanding to more volunteers, weapons, and ammunition types.</li></ul><h3><strong>4. Shimadzu / ASMS: Multi-Residue Pesticide Analysis in Norbixin colour additive oleoresin using GC-MS/MS</strong></h3><ul><li>Poster</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/ASMS_2025_MP_255_a0fd319c1d.pdf"><strong>Full PDF for download</strong></a></li></ul><p>Norbixin is the yellow-(red) orange carotenoid, which in combination with bixin, constitutes for 80% of red-orange annatto dye. It is extracted from the pericarp of the seeds of Bixa Orellana (Figure 1). The annatto pigment has global economic significance, as it is one of the most widely used natural dyes to color food, cosmetics and pharmaceutical products</p><p>Owing to its large culinary uses and other diverse applications, use of chemical pesticides for its production in large quantities is imperative. Dye extraction process may result in concentration of pesticides and in turn contribute to adverse impact on human health when incorporated in various preparations. Hence quantitation of residual pesticides in norbixin colour additive becomes very important. As the oleoresin is a complex matrix for extraction, it is required to develop a rugged, sensitive and efficient method for residual pesticide analysis.</p><p>This study reports a highly sensitive method for simultaneous quantification of multiple pesticides in complex matrix of norbixin using modified <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library?mainauthorItems=1&amp;search=QuEChERS"><strong>QuEChERS</strong></a>[1] with triple quadrupole gas chromatography (GC-MS/MS) system. <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library?mainauthorItems=1&amp;search=GCMS-TQ8040+NX"><strong>GCMS-TQ8040 NX</strong></a>, manufactured by Shimadzu Corporation Japan, was used to quantify residual pesticides in Norbixin oleoresin sample</p><h4><strong>Conclusion</strong></h4><ul><li>This study shows that the modified QuEChERS method combined with GC-MS/MS system is a reliable and efficient tool to quantify residual pesticides in norbixin sample. Although oleoresin is a complex matrix, the modified QuEChERS method significantly reduces interference.&nbsp;</li><li>Also, highly sensitive Shimadzu GC-MS/MS allows trace level detection even after multifold dilution of sample. This helps in reducing contamination and enhancing ruggedness resulting in reproducible detection of analytes.&nbsp;</li><li>The combination of sensitive instrument and reliable method enables its use in testing laboratories for multi-residue analysis of Norbixin oleoresin.</li></ul>

News from LabRulezGCMS Library - Week 31, 2025

News from LabRulezLCMS Library - Week 31, 2025

<p><strong>Our Library never stops expanding. What are the most recent contributions to LabRulezICPMS Library in the week of 28th July 2025? Check out new documents from the field of spectroscopy/spectrometry and related techniques!</strong></p><blockquote><p><span style="font-size:20px;">👉 </span><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/library"><span style="font-size:20px;"><strong>SEARCH THE LARGEST REPOSITORY OF DOCUMENTS ABOUT SPECTROSCOPY/SPECTROMETRY RELATED TECHNIQUES</strong></span></a></p></blockquote><blockquote><p><strong>👉 Need info about different analytical techniques?</strong> Peek into <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/library"><strong>LabRulezLCMS</strong></a> or <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library"><strong>LabRulezGCMS</strong></a> libraries.</p></blockquote><p>This week we bring you brochure by <strong>Anton Paar </strong>and<strong> </strong>application notes by<strong> Agilent Technologies, Metrohm,</strong> <strong>Shimadzu </strong>and<strong> Thermo Fisher Scientific!</strong></p><h3><strong>1. Anton Paar: Solutions from Upstream to Downstream</strong></h3><ul><li>Brochure</li><li><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/labrulez-bucket-strapi-h3hsga3/XPAIP_159_EN_D_Brochure_Petroleum_Industry_screen_6548668eb5.pdf"><strong>Full PDF for download</strong></a></li></ul><p>Anton Paar offers a comprehensive portfolio of high-precision analytical instruments for the <strong>petroleum industry</strong>, supporting the entire value chain from upstream exploration to downstream refining and testing. Their technologies help optimize key processes such as crude oil extraction, fuel formulation, lubricant development, asphalt quality control, and product certification. With a focus on <strong>automation, speed, safety, and compliance</strong>, the company enables more efficient, sustainable, and standardized workflows.</p><p>In <strong>upstream operations</strong>, Anton Paar solutions support the evaluation of crude oil properties, aiding decisions on drilling strategy, reservoir yield, and transport readiness. Measurements such as density, viscosity, and rheological behavior under various temperature and pressure conditions help optimize extraction potential and simulate real reservoir conditions. These tools are essential for enhancing recovery rates and minimizing costs.</p><p>In <strong>refineries</strong>, their instruments streamline fuel, lubricant, and asphalt testing through automated and robust measurement platforms. For fuels, Anton Paar enables precise determinations of flash points, distillation ranges, oxidation stability, and cold flow behavior. In lubricant production, their analyzers assess viscosity, consistency, and elemental contamination. Asphalt and bitumen analysis includes penetration, softening point, density, and rheology measurements to ensure long-term durability and regulatory compliance.</p><p>Finally, Anton Paar supports <strong>midstream logistics and third-party testing labs</strong> with tools for product identification, contamination checks, and custody transfer verification. Their automated, digital systems enhance data integrity and traceability while minimizing operator intervention. Whether for on-site process control or independent quality assessment, Anton Paar delivers trusted solutions to maximize performance and reduce risk across the petroleum sector.</p><h3><strong>2. Agilent Technologies: Accurate Elemental Analysis of Drinking Water per Bureau of Indian Standards by ICP-MS&nbsp;</strong></h3><p><strong>Fast, simple, compliant method using an Agilent </strong><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/library?mainauthorItems=10&amp;search=7850+ICP-MS"><strong>7850 ICP-MS </strong></a><strong>and SPS 4 Autosampler</strong></p><ul><li>Application note</li><li><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/labrulez-bucket-strapi-h3hsga3/an_drinking_water_bureau_indian_standards_icp_ms_5994_8402en_agilent_7496f27986.pdf"><strong>Full PDF for download</strong></a></li></ul><p>The provision of clean and safe drinking water from a dependable, uncontaminated supply is essential for public health. However, many freshwater sources are compromised by pollutants from domestic and industrial wastewater, as well as activities related to agriculture, mining, forestry, and construction. These contaminants can pose significant risks to human health. In recent years, heavy metals and other toxic elements have received significant attention in environmental investigations. In response to growing concerns about food and water safety, regulatory authorities in India, such as the Bureau of Indian Standards (BIS) and the Food Safety and Standards Authority of India (FSSAI), have established stringent regulations for drinking water analysis to ensure consumer safety.</p><p>Laboratories in India use various analytical techniques, including Flame Atomic Absorption Spectroscopy (FAAS), Inductively Coupled Plasma Optical Emission Spectroscopy (ICP-OES), and Inductively Coupled Plasma Mass Spectrometry (ICP-MS), to analyze drinking water. The choice of technique often depends on the number of elements and the concentration range required for the analysis. With the inclusion of uranium in the list of elements specified by BIS regulations, and to ensure preparedness for future updates, ICP-MS is increasingly favored for water analyses. Advantages of ICP-MS include its high sensitivity, low detection limits, wide elemental coverage, and fast, multielement capabilities.</p><p>The <a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/library?mainauthorItems=10&amp;search=7850+ICP-MS"><strong>Agilent 7850 ICP-MS</strong></a> provides drinking water testing laboratories with a comprehensive solution for analyzing multiple elements—including uranium—in drinking water, thereby fulfilling BIS mandatory requirements. A preset method assists the accurate and precise determination of 26 elements, including all 21 elements specified in the standards, in a quick, single run, enabling high sample throughput.&nbsp;</p><p>The 7850 ICP-MS uses Octopole Reaction System (ORS4 ) technology and optimized helium (He) collision mode to remove polyatomic ion interferences in routine applications.2 He mode effectively separates polyatomic ions from analyte ions based on their kinetic energies. As polyatomic ions pass through the ORS4 containing helium gas, they collide more frequently with helium atoms due to their larger collision cross-sections than smaller analyte ions, losing more energy. Upon exiting the cell, the lower-energy polyatomic ions are rejected using kinetic energy discrimination (KED). Meanwhile, analyte ions retain sufficient energy to pass through the KED barrier to the quadrupole and detector. This process removes polyatomic ions from the ion beam, enabling more accurate results for all analytes using a single gas mode.</p><h4><strong>Results and discussion&nbsp;</strong></h4><h5><strong>Detection limits&nbsp;</strong></h5><p>During method development, data was collected for all 26 elements. The Instrument Detection Limits (IDLs) were calculated from the calibration graphs (3 x standard deviation (SD) of the concentration of calibration blanks), while the dilution-adjusted DLs take account of the dilution factor of 1.25x. The DLs reported in Table 2 are well below the maximum permissible limits (MPLs) specified in the three BIS standards, confirming the suitability of the 7850 ICP-MS for the determination of trace elements in drinking water.</p><h4><strong>Conclusion&nbsp;</strong></h4><p>The Agilent 7850 ICP-MS successfully measured 26 elements in bottled and tap water samples using a single He KED method for all elements. This method adhered to the detection limits and QC requirements defined by the Bureau of Indian Standards (BIS 10500, BIS 14543, and BIS 13428), including the updated requirements for the measurement of uranium.&nbsp;</p><p>Using the low matrix preset method and autotuning routine within the Agilent ICP-MS MassHunter software streamlined the analytical workflow, minimizing setup time while ensuring accurate and interference-free results. Excellent recoveries of the certified elements in NIST 1643f Trace Elements in Water SRM confirmed the accuracy of the method for those elements.&nbsp;</p><p>The 7850 ICP-MS demonstrated good stability throughout the analysis of 130 solutions, making it a robust tool for quality and safety analysis of drinking water in accordance with Indian government standards.</p><h3><strong>3. Metrohm: Determining phosphate concentration with Raman spectroscopy</strong></h3><p><strong>A rapid and reagent-free alternative to chromatography and other</strong><br><strong>wet chemical methods</strong></p><ul><li>Application note</li><li><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/labrulez-bucket-strapi-h3hsga3/an_rs_049_download_c8d1992d32.pdf"><strong>Full PDF for download</strong></a></li></ul><p>Phosphates are vital inorganic compounds found extensively in nature and created by industrial processes. They play a crucial role in biological systems and are essential for life. In agriculture, phosphates are a primary component of fertilizers, enhancing soil fertility and increasing crop yields. Industrially, they are used in detergents, food additives, and as corrosion inhibitors. Raman spectroscopy, combined with PLS (Partial Least Squares) modeling, rapidly and quantitatively determines total phosphate concentration. Compared to other techniques like thermometric titration, Raman requires minimal sample preparation and accurately determines phosphate concentration over several orders of magnitude. Furthermore, Raman analysis is accomplished in a few minutes, compared to the longer analysis time required for chromatography and other wet chemical methods.</p><h4><strong>CURRENT METHODS FOR PHOSPHATE ANALYSIS</strong></h4><p>Phosphate content is traditionally analyzed by wet chemical colorimetric methods. In colorimetry, a colorforming reagent reacts with phosphates in solution to form a reaction product with a measurable color change. Ion chromatography is also used for quantitative analysis of phosphate ions, especially at low concentrations. While effective, both methods require extensive and time-consuming sample preparation. Ion chromatography is quite sensitive but requires several minutes to complete a determination. Additionally, these methods can generate waste that can damage the environment and are expensive to dispose of properly</p><h4><strong>PHOSPHATE ANALYSIS WITH </strong><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/library?mainauthorItems=220&amp;search=MIRA+XTR"><strong>RAMAN</strong></a></h4><p>Raman spectroscopy can be used for both speciation analysis and quantification using the unique spectral fingerprint of phosphoric acid’s protonation states. It is sensitive and nondestructive, making it ideal for the analysis of fast, in-process measurements. This Application Note demonstrates Raman’s ability to determine phosphate concentration over a wide range.&nbsp;</p><h4><strong>RESULTS&nbsp;</strong></h4><p>The principal Raman band for phosphate ions, observed between 850 to 950 cm−1 [1], changes with the protonation state of the molecule. Deprotonation occurs as a function of concentration and the phosphate peak ranges from 890 to 897 cm−1, with lower sample concentrations shifting to lower wavenumbers and intensities (Figure 2). This band was used for quantitative analysis of total phosphate ion concentration.</p><h4><strong>CONCLUSION</strong></h4><p>Raman spectroscopy offers a reliable and efficient method for quantitative analysis of total phosphates in solution. Its advantages include minimal sample preparation, nondestructive analysis, and high accuracy over a broad concentration range. This technique is particularly valuable for industrial applications where rapid and accurate phosphate determination is crucial for quality control and regulatory compliance.</p><h3><strong>4. Shimadzu: Determination of 23 Nutritional, Essential and Toxic Elements in Urine by ICP-MS Using Alkaline Dilution</strong></h3><ul><li>Application note</li><li><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/labrulez-bucket-strapi-h3hsga3/an_05_sca_116_013_en_7b298cd6e2.pdf"><strong>Full PDF for download</strong></a></li></ul><h4><strong>User Benefits</strong></h4><ul><li>Urine calibrator allows for simple preparation and quick measurement of 23 elements&nbsp;</li><li>Alkaline media ensures safe determination of iodine and excellent mercury washout capabilities&nbsp;</li><li><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/library?instrumentationItems=22&amp;mainauthorItems=1&amp;search=LabSolutions"><strong>LabSolutions</strong></a> ICPMS allows for high degree of automation by Extended Rinsing function and e.g. control of QC sample or internal standard recovery</li></ul><p>The analysis of nutritional, essential, and toxic elements in urine is a critical tool for assessing human health, environmental exposure, and metabolic function. Urine serves as a noninvasive biological matrix that reflects the body's excretion of trace elements, providing valuable insights into nutritional deficiencies, toxic metal exposure, and the status of essential minerals.&nbsp;</p><p>Inductively Coupled Plasma Mass Spectrometry (ICP-MS) is a highly sensitive and precise analytical technique that enables the detection of trace elements at ultra-low concentrations, making it ideal for comprehensive urine analysis.</p><h4><strong>Configuration &amp; Measurement Condition&nbsp;</strong></h4><p>The <a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/library?mainauthorItems=1&amp;search=ICPMS-2050+LF"><strong>ICPMS-2050 LF</strong></a> system configuration is summarized in Table 3. More than 20 elements have been selected for quantification (Table 4). To remove interferences the ICPMS-2050 highly efficient collisionand reaction cellwas applied by adding He or H2. In most cases the trace region is of interest. To improve the precision in the low-end trace region all calibration curves (Fig. 2) are inversely weighted (1/I).</p><h4><strong>Conclusion&nbsp;</strong></h4><p>Sample cycle times (including rinse) of below 3 minutes can be achieved without using complex sample injection techniques. This short time can be achieved by the collision/reaction cell’s extreme low gas switching times (&lt;5 sec.) and features like ProActive Rinsing, which allows to already start rinsing before the actual measurement is finished. This is possible because the remaining sample in the capillary is further injected (measured), before rinse solution reachesthe nebulizer. For routine use, the ICPMS-2050 LF running alkaline media is highly suitable for analyzing nutritional, essential, and toxic elementsin urine samples, even including iodine.</p><h3><strong>5. Thermo Fisher Scientific: Steel analysis: ARL X900 XRF Spectrometer with universal goniometer</strong></h3><ul><li>Application note</li><li><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/labrulez-bucket-strapi-h3hsga3/steel_analysis_arl_x900_xrf_spectrometer_an41425_en_5ad9805407.pdf"><strong>Full PDF for download</strong></a></li></ul><p>Ferrous base materials are very important products in this world because they are the foundation in many applications such as building, automotive, and many manufacturing processes. It is important to accurately analyze these materials to confirm compliance with their chemical specifications and allow for high quality and efficient production.&nbsp;</p><h4><strong>Irons&nbsp;</strong></h4><p>There are several kinds of irons which are distinguished by their composition and use. They belong to two main categories:&nbsp;</p><ul><li>Pig iron, also called hot metal, forms the basic material for the manufacture of steel&nbsp;<span>&nbsp;</span></li><li>Cast irons, are used to produce semi-manufactured products&nbsp;</li></ul><p>From a metallographic point of view, a distinction can be made between white cast iron, with a cementite structure and grey cast iron which contains free graphite either in the form of laminae or nodules. This makes grey cast iron inhomogeneous and therefore difficult to analyze. Alloy cast irons also exist where alloying elements such as nickel, chromium, manganese, copper, etc. are added to improve hardness, corrosion resistance, or engineering properties.</p><h4><strong>Instrument parameters and conditions&nbsp;</strong></h4><p>The <a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/products/1978"><strong>ARL X900 XRF</strong></a> Spectrometer is equipped with the unique proprietary moiré fringe goniometer. Speed, flexibility, and reliability of analysis are guaranteed thanks to the ingenious friction-free positioning system. Up to nine crystals and four collimators can be fitted. With the two detectors (flow proportional and scintillation counters), precise elemental analysis from boron to californium is possible. Additionally, the spectrometer can accommodate up to 24 fixed monochromator channels alongside the goniometer or up to 32 fixed monochromator channels when no goniometer is fitted.&nbsp;</p><p>The ARL X900 XRF Spectrometer can be calibrated using commercially available certified reference material (CRM) standards or well analyzed samples from the user.&nbsp;</p><p>It should be stressed that an XRF spectrometer is a very accurate comparator, but the accuracy of the final analysis is entirely dependent on the quality of the standards used for calibration and on the care and reproducibility of sample preparation which must be identical for CRMs and for routine samples as well.</p><h4><strong>Conclusion&nbsp;</strong></h4><p>Analysis of steels can be performed with ease using the ARL X900 Simultaneous-Sequential XRF Spectrometer. The performance of the moiré fringe goniometer is such that it can be used for analysis of any elements that are not fitted as fixed channels. The analysis on the goniometer is done while the fixed channels are also measuring. In addition, it can be used as a backup in case of failure of any of the fixed channels.&nbsp;</p><p>Appropriate calibrations for steel alloys can be delivered turnkey from Thermo Fisher Scientific. In this case, the commissioning time of the spectrometer is reduced to a minimum.&nbsp;</p><p>The precision is excellent in these matrix types for routine or R&amp;D analysis, especially when an innovative, high counting fixed channel monochromator is used for elements like Ni, Co or Mo.&nbsp;</p><p>Furthermore, operation is made easy through the advanced Thermo Scientific™ <a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/products/2029"><strong>OXSAS™ Software</strong></a> that operates with the latest Microsoft Windows® package.</p>

News from LabRulezICPMS Library - Week 31, 2025

<p><strong>Halomethanes (HMs) are key contributors to ozone depletion and climate forcing, yet their natural sources remain undercharacterized. This study examines bioweathered Lopingian Kupferschiefer black shale in SW Poland as a potential source of HM emissions. Rich in fossil organic matter (FOM) and iron-bearing minerals, the shale was found to emit various chlorinated and brominated mono- to tetrahalomethanes.</strong></p><p>Using gas chromatography, the researchers propose a mechanism involving Fe³⁺-catalyzed abiotic reactions with organic precursors and halides. The findings identify a previously unrecognized deep subsurface source of halomethanes and report, for the first time, natural emission of tetrachloromethane.</p><blockquote><h4><strong>The original article</strong></h4><h4><a target="_blank" rel="noopener noreferrer" href="https://pubs.acs.org/doi/10.1021/acs.estlett.5c00593"><strong>Emissions of Halomethanes from Bioweathered Lopingian Kupferschiefer Black Shale (Fore-Sudetic Monocline, SW Poland)</strong></a></h4><p>Michał Zalesko*, Robert Stasiuk, Renata Matlakowska</p><p>Environ. Sci. Technol. Lett. 2025, XXXX, XXX, XXX-XXX</p><p><a target="_blank" rel="noopener noreferrer" href="https://doi.org/10.1021/acs.estlett.5c00593">https://doi.org/10.1021/acs.estlett.5c00593</a></p><h6>licensed under <a target="_blank" rel="noopener noreferrer" href="https://creativecommons.org/licenses/by/4.0/"><strong>CC-BY 4.0</strong></a></h6></blockquote><p><strong>Selected sections from the article follow. Formats and hyperlinks were adapted from the original.</strong></p><p>Halogenated methane derivatives (halomethanes, HMs) are significant sources of atmospheric halogens, which play an important role in ozone depletion and contribute to radiative forcing. <a href="javascript:void(0);">(1,2)</a> The most abundant HM in the atmosphere is chloromethane, which is responsible for 16.9% of tropospheric chlorine. <a href="javascript:void(0);">(2)</a> In addition to anthropogenic sources, several natural sources of HMs have been described. <a href="javascript:void(0);">(3,4)</a> However, the amount of naturally produced HMs appears to be underestimated. <a href="javascript:void(0);">(2)</a> Bahlmann et al. (2019) suggest the existence of a major missing source of atmospheric chloromethane. <a href="javascript:void(0);">(5)</a></p><p>Therefore, it is worth considering what other natural sources exist. Studies by Keppler et al. (2000) indicate that HMs were formed from natural organic matter through abiotic processes that were catalyzed by Fe<sup>3+</sup>. <a href="javascript:void(0);">(6,7)</a> In 2009, Huber et al. presented the mechanism of trihalomethane formation from dihydroxylated monocyclic aromatic hydrocarbons (DMAHs) in the presence of Fe<sup>3+</sup> and (H<sub>2</sub>O<sub>2</sub>). The organic compound is oxidized and simultaneously halogenated by halide radicals in the presence of reactive oxygen species (ROS), both arising from a Fenton-like reaction between H<sub>2</sub>O<sub>2</sub>, Fe<sup>3+</sup>, and halides. <a href="javascript:void(0);">(8−10)</a></p><p>In our studies, we consider whether iron-catalyzed HM formation processes can occur in highly mineralized deposits of fossil organic matter (FOM). It is worth noting that FOM, in the form of kerogen, is considered to be the largest reservoir of organic carbon on Earth. It is estimated that kerogen contains ∼15,000,000 Gt of fossil organic carbon, an amount that significantly exceeds the amount (∼4,130 Gt) found in fossil fuels (such as gas, oil and coal). <a href="javascript:void(0);">(11)</a></p><p>This study focuses on the organic-rich deep black shale environment, represented by the Kupferschiefer black shale (BS), which contains both FOM (1–30 wt %, average 6 wt %, corresponding to type II kerogen) and Fe-containing minerals. <a href="javascript:void(0);">(12−14)</a> The extractable fraction of FOM consists of long-chain saturated and unsaturated hydrocarbons, polycyclic aromatic hydrocarbons (PAHs), and acid esters. <a href="javascript:void(0);">(15)</a> The ore minerals in BS are mainly represented by bornite [Cu<sub>5</sub>FeS<sub>4</sub>], chalcocite [Cu<sub>2</sub>S], digenite [Cu<sub>9</sub>S<sub>5</sub>], chalcopyrite [CuFeS<sub>2</sub>], pyrite [FeS<sub>2</sub>], sphalerite [ZnS], galena [PbS], covellite [CuS], and minerals from the tennantite–tetrahedrite series [(Cu, Fe)<sub>12</sub>As<sub>4</sub>S<sub>13</sub>–(Cu, Fe)<sub>12</sub>Sb<sub>4</sub>S<sub>13</sub>]. <a href="javascript:void(0);">(16)</a></p><p>Previous studies indicate colonization by microorganisms and the bioweathering of outcropped Kupferschiefer BS profiles. <a href="javascript:void(0);">(15)</a> This study confirmed that FOM underwent enzymatic oxidation, mediated primarily by chemoorganoheterotrophic bacteria. Furthermore, the dissimilative enzymatic oxidation of primary sulfidic minerals by chemolithotrophic bacteria was detected.</p><p>This study aims to investigate whether bioweathered BS can be a source of HM emissions. In addition, we attempted to predict potential substrates and factors of HM formation. As sources of these substrates and factors, we considered BS bioweathering products and mine water (MW) (<a target="_blank" rel="noopener noreferrer" href="https://pubs.acs.org/doi/suppl/10.1021/acs.estlett.5c00593/suppl_file/ez5c00593_si_001.pdf">Figure SI1/1</a>): (1) as potential substrates, we indicated monocyclic aromatic hydrocarbons (MAHs) formed by FOM bioweathering; (2) as a halogenation factor, we indicated Fe<sup>3+</sup> arising from the oxidation of primary Fe<sup>2+</sup>-containing minerals; (3) as a source of halides, we indicated high saline MW and secondary minerals on the surface of weathered BS.</p><p>In order to achieve these objectives, we studied bioweathered BS covered by secondary minerals and MW. The following studies were conducted: (1) detection and identification of HMs; (2) prediction of MAHs in FOM extracted from bioweathered BS and MW; (3) detection of Fe and halides in bioweathered BS and MW; and (4) Fe<sup>3+</sup> and halide detection in secondary minerals present on the surface of bioweathered BS.</p><p>This experimental approach has enabled us to propose a hypothetical mechanism of HM formation in deep underground environments and reveal a previously unknown natural source of HMs.</p><h4><strong>Methods and Materials</strong></h4><h5><strong>Extraction of Volatile Organic Compounds</strong></h5><p>Volatile organic compounds were extracted using a modified EPA Method 5021A (2014). <a href="javascript:void(0);">(17)</a> A hundred grams of BS were placed in 100 mL bottles with septa, and 50 mL of methanol was added. The mixture was incubated at 50 °C for 72 h. For analysis, gas samples were collected using a gastight syringe (Hamilton Company, USA), or solid-phase microextraction (SPME, 65 μm, PDMS/DVB, Supelco, USA) was used. <a href="javascript:void(0);">(18)</a> More detailed information is provided in <a target="_blank" rel="noopener noreferrer" href="https://pubs.acs.org/doi/suppl/10.1021/acs.estlett.5c00593/suppl_file/ez5c00593_si_001.pdf">SI1</a>.</p><h5><strong>Extraction of Bituminous and Dissolved Organic Compounds</strong></h5><p>Organic compounds were extracted from BS and MW using a mixture of dichloromethane/methanol with an automatic Soxhlet apparatus (SER 158, Velp, Italy) and chloroform in a separatory funnel, respectively. More detailed information is provided in <a target="_blank" rel="noopener noreferrer" href="https://pubs.acs.org/doi/suppl/10.1021/acs.estlett.5c00593/suppl_file/ez5c00593_si_001.pdf">SI1</a>.</p><h5><strong>Gas Chromatography with Mass Spectrometry (GC-MS) and Electron Capture Detector (GC-ECD)</strong></h5><p>Volatile compounds were analyzed using GC-MS (Agilent <strong>GC</strong> <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library?mainauthorItems=10&amp;search=7890A"><strong>7890A</strong></a>, <strong>MS</strong> <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library?mainauthorItems=10&amp;search=5975c"><strong>5975c</strong></a>, Agilent Technologies, USA) and<a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library?mainauthorItems=10&amp;search=+GC-ECD"><strong> GC-ECD </strong></a>(GC 7890A, μECD, Agilent Technologies, USA), both equipped with a FS CAP VOCOL column (60 m × 0.25 mm I.D., 1.5 μm film thickness, Supelco, USA) according to modified EPA Method 8260(1986). <a href="javascript:void(0);">(19)</a> Commercial solutions of CH<sub>3</sub>Cl (Restek, Germany), CHCl<sub>2</sub>, and CHCl<sub>3</sub> (VWR Chemicals, USA), as well as the VOA Stock Mix 8260B MegaMix Calibration Mix (Restek, Germany), were used as external standards.</p><p>Compounds extracted from BS and MW were analyzed by GC-MS (Agilent GC 7890A, MS 5975c) using an HP5-MS column (30 m × 0.25 mm I.D., 0.25 μm film thickness, Agilent Technologies, USA). The obtained mass spectra were compared with the <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/products/887"><strong>Wiley 3.2 database</strong></a> (The Wiley Registry of Mass Spectral Data, eighth edition). More details are provided in <a target="_blank" rel="noopener noreferrer" href="https://pubs.acs.org/doi/suppl/10.1021/acs.estlett.5c00593/suppl_file/ez5c00593_si_001.pdf">SI1</a>.</p><h5><strong>Inductively Coupled Plasma with Mass Spectrometry (ICP-MS)</strong></h5><p>The elemental analysis of the weathered BS and MW was determined by ACME Analytical Laboratories Ltd. (Vancouver, BC, Canada). LF202 Total Whole Rock Characterization with AQ200 add-on (LF302 + LF100-EXT) and SO200 – ICP-MS Analysis of Natural Waters were conducted on BS and MW samples, respectively.</p><h5><strong>X-ray Fluorescence (XRF)</strong></h5><p>Detection of Fe, Cl, and Br in BS was performed by using a Bruker S1 Titan Hand-held ED-XRF Analyzer.</p><h5><strong>Scanning Electron Microscopy (SEM) with Energy Dispersive X-ray Spectroscopy (EDS)</strong></h5><p>Analysis was performed using backscattered and secondary electron techniques with a JEOL JSM-6380LA SEM instrument (JEOL Co., Japan). The chemical composition was determined by using a CAMECA SX100 microprobe (CAMECA, France). More details are provided in <a target="_blank" rel="noopener noreferrer" href="https://pubs.acs.org/doi/suppl/10.1021/acs.estlett.5c00593/suppl_file/ez5c00593_si_001.pdf">SI1</a>.</p><h5><strong>X-ray Powder Diffraction (XRD) Analyses</strong></h5><p>XRD analyses of powdered samples were conducted using a PHILIPS X’PERT PRO diffractometer (PANalytical B.V., The Netherlands). The samples were manually ground in an agate mortar, mounted on a standard metal holder, and irradiated with CoKα radiation. Data was collected over a 2Θ range of 2.505° to 95.996° in step-scan mode, with a step size of 0.001° 2Θ and a count time of 1 s per step.</p><h4><strong>Results and Discussion</strong></h4><h5><strong>Identification of HM Emitted from the Weathered BS</strong></h5><p>Using GC-MS with the headspace extraction method, chloromethane and dichloromethane were identified in all BS samples analyzed with high probability (86–94%) (<a target="_blank" rel="noopener noreferrer" href="https://pubs.acs.org/doi/10.1021/acs.estlett.5c00593#fig1">Figure 1</a>; <a target="_blank" rel="noopener noreferrer" href="https://pubs.acs.org/doi/suppl/10.1021/acs.estlett.5c00593/suppl_file/ez5c00593_si_001.pdf">Figure SI2/1</a>). HMs were identified in all GC-ECD analyses. Using SPME, bromodichloromethane, dibromochloromethane, dichloromethane, tetrachloromethane, and trichloromethane were identified in all BS samples. Chloromethane was detected in all BS samples, except BS2, while dibromomethane was present exclusively in BS2. Relative abundance (<i>z</i>-score) analyses indicate higher emissions of HM from samples collected at site TS2 (<a target="_blank" rel="noopener noreferrer" href="https://pubs.acs.org/doi/10.1021/acs.estlett.5c00593#fig1">Figure 1</a>).</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Environ_Sci_Technol_Lett_2025_Figure_1_A_relative_abundance_of_H_Ms_found_in_B_Ss_through_SPME_extraction_and_GC_ECD_analysis_5332017a52.jpg" alt="Environ. Sci. Technol. Lett. 2025: Figure 1. A relative abundance of HMs found in BSs through SPME extraction and GC-ECD analysis. An asterisk indicates compounds identified by GC-MS. GC-ECD chromatograms, a detailed list, and mass spectra of the identified HMs can be found in SI2 (Table SI2/1–2; Figures SI2/1–8). GC-ECD chromatograms of standards and controls can be found in SI2 (Figures SI2/9–11)." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Environ_Sci_Technol_Lett_2025_Figure_1_A_relative_abundance_of_H_Ms_found_in_B_Ss_through_SPME_extraction_and_GC_ECD_analysis_5332017a52.jpg 245w," sizes="100vw" width="1750" height="477"></p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Environ_Sci_Technol_Lett_2025_Figure_SI_2_7_Chromatograms_of_the_volatile_phase_obtained_from_methanol_extracts_of_TS_1_GC_ECD_SPME_43d9f8c91d.jpg" alt="Environ. Sci. Technol. Lett. 2025: Figure SI2/7. Chromatograms of the volatile phase obtained from methanol extracts of TS1 (GC-ECD, SPME)." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Environ_Sci_Technol_Lett_2025_Figure_SI_2_7_Chromatograms_of_the_volatile_phase_obtained_from_methanol_extracts_of_TS_1_GC_ECD_SPME_43d9f8c91d.jpg 80w," sizes="100vw" width="563" height="1090"></p><h5><strong>Prediction of Potential Organic Substrates for HM Formation in Bioweathered BS and MW</strong></h5><p>Potential organic substrates were predicted with Level 2 confidence according to Koelmel et al. 2022. <a href="javascript:void(0);">(20)</a> In the extractable fraction of BSs several MAHs are present: benzoic acid and 1,2-dicarboxybenzene derivatives (<a target="_blank" rel="noopener noreferrer" href="https://pubs.acs.org/doi/10.1021/acs.estlett.5c00593#fig2">Figure 2</a>). The MAH compounds may undergo enzymatic oxidation through microbial dioxygenases and monooxygenases to DMAHs, such as protocatechuate and catechol. <a href="javascript:void(0);">(15)</a> Esters of 1,2-dicarboxybenzene acids can be deesterified by bacterial esterases. <a href="javascript:void(0);">(21)</a> In MWs, the diversity of 1,2-dicarboxybenzene derivatives is higher, which may indicate the ongoing degradation and transformation of organic matter (<a target="_blank" rel="noopener noreferrer" href="https://pubs.acs.org/doi/10.1021/acs.estlett.5c00593#fig2">Figure 2</a>). The presence of dioxygenases, monooxygenases and esterases was previously confirmed in a metagenome and metaproteome of microbiocenoses that inhabit the bioweathered BS. <a href="javascript:void(0);">(15)</a></p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/ENVIRO_3_7fd06dfb40.jpg" alt="Environ. Sci. Technol. Lett. 2025: Figure 2. The abundance of benzoic acid and 1,2-dicarboxylic acid derivatives predicted with Level 2 confidence in BSs and MWs. Mass spectra of the predicted organic compounds are provided in SI3." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_ENVIRO_3_7fd06dfb40.jpg 245w," sizes="100vw" width="2100" height="500"></p>

Emissions of Halomethanes from Bioweathered Lopingian Kupferschiefer Black Shale (Fore-Sudetic Monocline, SW Poland)

Quantitative Assessment of a Novel Device Designed for Patient-centric Sampling of Dried Plasma Using Targeted Proteomics

Controllable Ion-Repulsion Enables Rapid and Trace-Level Detection of Hydrophobic Sulfonylurea Herbicides with ICPMS/MS without the Organic Mode

<p><strong>In the week of August 4, the following webinars await you in the field of gas / solid phase and especially Raman, FTIR, GC and GC/MS.</strong></p><blockquote><p><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/webinars"><strong>👉 DETAILS AND REGISTRATION IN THE WEBINARS SECTION</strong></a></p><p><strong>👉 Search and filter in the largest global database</strong> with over <strong>4 500 GC, LC, MS and spectroscopy webinars</strong>.</p></blockquote><h5><strong>1. MDPI: Developments in Chromatographic Separations for Forensic Analysis</strong></h5><ul><li><strong>Wednesday, August 6, 2025, 15:00 CEST</strong></li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/webinar/5357">Registration</a></li></ul><p>Explore new forensic applications of GC and GC/MS in this expert-led webinar, from xylazine detection to fingerprint age estimation using GC-TOFMS. Free registration with certificate!</p><h5><strong>2. Metrohm: Practical Raman Applications: From Polymers to Process Control</strong></h5><ul><li><strong>Wednesday, August 6, 2025, 19:00 CEST</strong></li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/webinar/5344">Registration</a></li></ul><p>Discover how modern Raman spectroscopy enables real-time, point-of-need chemical analysis with case studies in polymer, carbon, and quantitative routine workflows.</p><h5><strong>3. C&amp;EN: Analysis for Impurities in Fuel Cell Grade Hydrogen by Gas Chromatography</strong></h5><ul><li><strong>Thursday, August 7, 2025, 20:00 CEST</strong></li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/webinar/5303">Registration</a></li></ul><p>Explore how Agilent developed GC methods to analyze trace impurities in fuel cell-grade hydrogen. Learn why purity matters and which techniques ensure reliable hydrogen analysis.</p><h5><strong>4. Agilent Technologies: Ensuring Excellence: Cutting-Edge Techniques for Pharmaceutical Analysis [Spectroscopy]</strong></h5><ul><li><strong>Friday, August 8, 2025, 07:30 CEST</strong></li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/webinar/5310">Registration</a></li></ul><p>Explore UV-Vis, IR, and Raman automation in pharma research. Learn how elemental spectroscopy ensures safety and regulatory compliance in analysis.</p>

Webinars LabRulezGCMS Week 32/2025

<p><strong>In the week of August 4, the following webinars await you in the field of liquid phase and especially HPLC and LC/MS.</strong></p><blockquote><p><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/webinars"><strong>👉 DETAILS AND REGISTRATION IN THE WEBINARS SECTION</strong></a></p><p><strong>👉 Search and filter in the largest global database</strong> with over <strong>4 500 GC, LC, MS and spectroscopy webinars</strong>.</p></blockquote><h5><strong>1. Phenomenex: From Wavy to Wonderful: Solving HPLC Baseline Problems</strong></h5><ul><li><strong>Wednesday, August 6, 2025, 10:00 CEST</strong></li><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/webinar/5345">Registration</a></li></ul><p>Learn how to troubleshoot and prevent HPLC baseline problems with expert tips, common issues, and practical solutions for achieving a stable, reliable chromatographic baseline.</p><h5><strong>2. SCIEX: SCIEX OS software summer school – part 2: Compound optimization</strong></h5><ul><li><strong>Wednesday, August 6, 2025, 11:00 CEST</strong></li><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/webinar/5293">Registration</a></li></ul><p>Join us for part 2 of our live summer school series and continue building your confidence in SCIEX OS software.</p><h5><strong>3. SelectScience: Transforming forensic lab efficiency through digitalization</strong></h5><ul><li><strong>Wednesday, August 6, 2025, 17:00 CEST</strong></li><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/webinar/5346">Registration</a></li></ul><p>Discover how SLED enhanced forensic lab efficiency using Agilent CrossLab Connect for real-time monitoring, service insights, and digital transformation across 20,000+ cases.</p><h5><strong>4. Unchained Labs: Glow up with encapsulation efficiency (EE%) on Stunner AF</strong></h5><ul><li><strong>Thursday, August 7, 2025, 17:00 CEST</strong></li><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/webinar/5347">Registration</a></li></ul><p>Discover how Stunner AF simplifies EE% assays for LNPs by combining fluorescence, UV/Vis, and particle analysis—delivering more data with less hassle in a single 96-well plate.</p>

Webinars LabRulezLCMS Week 32/2025

<p><strong>In the week from August 4, the following webinars await you in the field of atomic and molecular spectroscopy and spectrometry</strong></p><blockquote><p><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/webinars"><strong>👉 DETAILS AND REGISTRATION IN THE WEBINARS SECTION</strong></a></p><p><strong>👉 Search and filter in the largest global database</strong> with over <strong>4 500 GC, LC, MS and spectroscopy webinars</strong>.</p></blockquote><h5><strong>1. Metrohm: Practical Raman Applications: From Polymers to Process Control</strong></h5><ul><li><strong>Wednesday, August 6, 2025, 19:00 CEST</strong></li><li><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/webinar/5344">Registration</a></li></ul><p>Discover how modern Raman spectroscopy enables real-time, point-of-need chemical analysis with case studies in polymer, carbon, and quantitative routine workflows.</p><h5><strong>2. Unchained Labs: Glow up with encapsulation efficiency (EE%) on Stunner AF</strong></h5><ul><li><strong>Thursday, August 7, 2025, 17:00 CEST</strong></li><li><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/webinar/5347">Registration</a></li></ul><p>Discover how Stunner AF simplifies EE% assays for LNPs by combining fluorescence, UV/Vis, and particle analysis—delivering more data with less hassle in a single 96-well plate.</p><h5><strong>3. Agilent Technologies: Back to Basics Mini Workshop: How ICP-QQQ Works</strong></h5><ul><li><strong>Thursday, August 7, 2025, 20:00 CEST</strong></li><li><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/webinar/3145">Registration</a></li></ul><p>During the workshop we will cover general theory on ICP-MS and what led to the development of the ICP-QQQ back in 2012.</p><h5><strong>4. Agilent Technologies: Ensuring Excellence: Cutting-Edge Techniques for Pharmaceutical Analysis [Spectroscopy]</strong></h5><ul><li><strong>Friday, August 8, 2025, 07:30 CEST</strong></li><li><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/webinar/5310">Registration</a></li></ul><p>Explore UV-Vis, IR, and Raman automation in pharma research. Learn how elemental spectroscopy ensures safety and regulatory compliance in analysis.</p>

Webinars LabRulezICPMS Week 32/2025

<p><strong>Whether you're servicing a GC/MS system or enhancing its performance, having access to high-quality spare parts is essential. Our curated selection includes tested, refurbished, and brand-new components from industry leaders like Agilent, Pfeiffer, and Edwards.</strong></p><p>From turbo pumps to analyzer assemblies with High-Efficiency Sources (HES), this list offers reliable solutions for maintaining vacuum integrity, boosting sensitivity, and ensuring long-term instrument uptime. Explore the detailed offers below and keep your GC/MS running at peak performance.</p><h5><strong>1. Agilent: 5977 EI Extraction Analyzer, G7077-69201 (Tested)</strong></h5><ul><li>Analyzer for Agilent 5977 GC/MS with EI. Ensures optimal performance in electron ionization workflows.</li><li><strong>Price:</strong> €6,875.00</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/bazaar/462">Detailed offer can be found here</a></li></ul><h5><strong>2. Agilent: 5977B HES Analyzer, G7077-67797 (Tested)</strong></h5><ul><li>High-Efficiency Source analyzer for 5977B GC/MSD. Enhances trace sensitivity; ideal for upgrades or service replacements.</li><li><strong>Price:</strong> €6,875.00</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/bazaar/461">Detailed offer can be found here</a></li><li>There are two analyzers of this type available – <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/bazaar/478">detailed information about the second one is available here</a>.</li></ul><h5><strong>3. Agilent: EI Extraction Analyzer, Support (G7077-67201) (Refurbished)</strong></h5><ul><li>Refurbished EI analyzer support module for Agilent 5977 GC/MS systems. Reliable component for electron ionization applications.</li><li><strong>Price: </strong>€6,875.00</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/bazaar/384">Detailed offer can be found here</a></li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Agilent_EI_Extraction_Analyzer_Support_4ad6b86679.jpg" alt="Agilent: EI Extraction Analyzer, Support (G7077-67201) (Refurbished)" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Agilent_EI_Extraction_Analyzer_Support_4ad6b86679.jpg 208w," sizes="100vw" width="1713" height="1285"></p><h5><strong>4. Agilent: GC/QQQ Rear Analyzer with Iris, Support (G7003-67212) (Tested)</strong></h5><ul><li>Rear analyzer assembly with iris for precise ion focusing in Agilent TQ GC/MS systems.</li><li><strong>Price: </strong>€6,875.00</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/bazaar/388">Detailed offer can be found here</a></li></ul><h5><strong>5. Agilent: IDP-10 Scroll pump with Valve for GC/QQQ, G7004-83011 (New)</strong></h5><ul><li>Oil-free scroll pump with integrated valve. Quiet, low-maintenance vacuum source for Agilent GC/QQQ systems.</li><li><strong>Price:</strong> €3,900.00</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/bazaar/441">Detailed offer can be found here</a></li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Agilent_IDP_10_Scroll_pump_with_Valve_for_GCQQQ_500f8f64ba.jpg" alt="Agilent: IDP-10 Scroll pump with Valve for GC/QQQ, G7004-83011 (New)" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Agilent_IDP_10_Scroll_pump_with_Valve_for_GCQQQ_500f8f64ba.jpg 208w," sizes="100vw" width="1700" height="1275"></p><h5><strong>6. Agilent: Popbridge Turbo Power Supply, G2589-80063 (Tested)</strong></h5><ul><li>OEM power supply for GC/MS. Delivers reliable high-performance power to turbo pumps and associated modules.</li><li><strong>Price:</strong> €1,900.00</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/bazaar/454">Detailed offer can be found here</a></li></ul><h5><strong>7. Agilent: QQQ Front Analyzer w/HES 2.0 Source, G7007-67312 (Tested)</strong></h5><ul><li>Front analyzer with HES 2.0 for Agilent GC/TQ systems. Designed for high ion transmission and enhanced robustness.</li><li><strong>Price:</strong> €6,875.00</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/bazaar/471">Detailed offer can be found here</a></li></ul><h5><strong>8. Agilent: QQQ Front Analyzer with Extractor Assembly, G7000‑67211 (New)</strong></h5><ul><li>OEM front analyzer with extractor lens for Agilent 7000 GC/MS. Boosts MS1 sensitivity and ion focusing efficiency.</li><li><strong>Price: </strong>€10,625.00</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/bazaar/391">Detailed offer can be found here</a></li></ul><h5><strong>9. Agilent: TURBO-V301 Navigator Turbo Pump with Controller (New)</strong></h5><ul><li>Compact, oil-free turbo pump with controller. Ideal for GC/MS, LC/MS and UHV applications.</li><li><strong>Price:</strong> €4,100.00</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/bazaar/379">Detailed offer can be found here</a></li></ul><h5><strong>10. Edwards: nEXT 200D200 V.160W Vacuum Pump (Tested)</strong></h5><ul><li>High-performance turbomolecular pump for MS and microscopy. Tested and suitable for high-vacuum applications.</li><li><strong>Price: </strong>€5,900.00</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/bazaar/456">Detailed offer can be found here</a></li></ul><h5><strong>11. Pfeiffer: Split Flow Pump, PMP03628F, G2597-80310 (Tested)</strong></h5><ul><li>High-efficiency split flow turbo pump for Agilent MS systems. Reliable vacuum solution with tested performance.</li><li><strong>Price:</strong> €5,900.00</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/bazaar/455">Detailed offer can be found here</a></li></ul><h5><strong>12. Pfeiffer: Turbo Pump HiPace 300 for GC 5975 Series, G3170-80162 (Refurbished)</strong></h5><ul><li>Refurbished Pfeiffer HiPace 300 turbo pump. Ensures stable vacuum in Agilent 5975 GC/MS systems with fast pump-down.</li><li><strong>Price:</strong> €6,000.00</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/bazaar/444">Detailed offer can be found here</a></li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Agilent_Pfeiffer_turbo_pump_Hi_Pace_300_for_GC_5975_series_9af4071a1e.jpg" alt="Pfeiffer: Turbo Pump HiPace 300 for GC 5975 Series, G3170-80162 (Refurbished)" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Agilent_Pfeiffer_turbo_pump_Hi_Pace_300_for_GC_5975_series_9af4071a1e.jpg 208w," sizes="100vw" width="1600" height="1200"></p>

Top GC/MS Spare Parts on the Marketplace – Tested, Refurbished & New

Article

Product

Events

Webinars

Application

Academy

Video

Poster

Scientists

Plastics

Environment

Food

Water

Health

Presentation

Scientific article

Interview

Toxicology

Popularization

Science and research

Software

Covid-19

Career

Laboratories

Various

PFAS 

Zaměření

Type of News

Focus

Everything from the world of analytical chemistry in one place. We connect people in solving their problems. At Labrulez you will find all the necessary information easily, quickly and clearly. Stop searching and start finding.

Top GC/MS Spare Parts on the Marketplace – Tested, Refurbished & New

Webinars LabRulezICPMS Week 32/2025

Webinars LabRulezLCMS Week 32/2025

Webinars LabRulezGCMS Week 32/2025

Controllable Ion-Repulsion Enables Rapid and Trace-Level Detection of Hydrophobic Sulfonylurea Herbicides with ICPMS/MS without the Organic Mode

Quantitative Assessment of a Novel Device Designed for Patient-centric Sampling of Dried Plasma Using Targeted Proteomics

Emissions of Halomethanes from Bioweathered Lopingian Kupferschiefer Black Shale (Fore-Sudetic Monocline, SW Poland)

News from LabRulezICPMS Library - Week 31, 2025

News from LabRulezLCMS Library - Week 31, 2025

News from LabRulezGCMS Library - Week 31, 2025

Upcoming events

Bruker at SOFT-TIAFT 2026

Thermo Fisher Scientific at SOFT/TIAFT 2026

Thermo Fisher Scientific Environmental & Food Safety Workshop Series 2026

Webinars

How to Perform Routine Quantification by FTIR: Tips & Tricks Workshop

Learn How FTIR Can Help You with Contamination and Poor Product Quality

Expanding the Evidence: New Data for More Reliable PFAS Analysis